Conservation of cofitness between ECD_03303 and ECD_02540 in Escherichia coli BL21

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03303 branched-chain amino acid ABC transporter ATPase 1.0 ECD_02540 multidrug efflux system 0.57 32
Escherichia coli ECOR27 1.00 NOLOHH_08555 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 NOLOHH_12620 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 75
Escherichia coli ECRC102 1.00 NIAGMN_14530 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 NIAGMN_18550 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA — —
Escherichia fergusonii Becca 1.00 EFB2_00368 High-affinity branched-chain amino acid transport ATP-binding protein LivF 1.00 EFB2_01243 Multidrug export protein EmrA low > 86
Escherichia coli ECRC101 1.00 MCAODC_07290 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 MCAODC_11305 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 87
Escherichia coli ECRC62 1.00 BNILDI_02950 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 BNILDI_11180 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 75
Escherichia coli Nissle 1917 1.00 ECOLIN_RS19755 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 ECOLIN_RS14965 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 55
Escherichia coli ECRC98 1.00 JDDGAC_20390 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 JDDGAC_24445 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 86
Escherichia coli ECRC99 1.00 KEDOAH_11380 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 KEDOAH_07355 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA — —
Escherichia coli ECRC100 1.00 OKFHMN_16760 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 OKFHMN_20780 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 80
Escherichia coli BW25113 1.00 b3454 livF ATP-binding component of leucine transport (VIMSS) 1.00 b2685 emrA multidrug efflux system (NCBI) low > 76
Escherichia coli ECOR38 1.00 HEPCGN_15580 livF high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 1.00 HEPCGN_19975 emrA multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_00249 High-affinity branched-chain amino acid transport ATP-binding protein LivF 1.00 OHPLBJKB_01048 Multidrug export protein EmrA low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF552 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) 0.89 GFF1592 Multidrug resistance protein A low > 78
Klebsiella michiganensis M5al 0.95 BWI76_RS26330 ABC transporter ATP-binding protein 0.82 BWI76_RS22095 multidrug export protein EmrA low > 92
Enterobacter sp. TBS_079 0.95 MPMX20_04330 High-affinity branched-chain amino acid transport ATP-binding protein LivF 0.87 MPMX20_03563 Multidrug export protein EmrA low > 85
Enterobacter asburiae PDN3 0.93 EX28DRAFT_4286 ABC-type branched-chain amino acid transport systems, ATPase component 0.85 EX28DRAFT_2768 efflux pump membrane protein (multidrug resistance protein A) low > 76
Pectobacterium carotovorum WPP14 0.88 HER17_RS00515 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 0.70 HER17_RS04465 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 75
Dickeya dadantii 3937 0.88 DDA3937_RS00680 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 0.68 DDA3937_RS16760 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 74
Dickeya dianthicola 67-19 0.88 HGI48_RS20710 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 0.66 HGI48_RS16830 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA 0.52 58
Rahnella sp. WP5 0.86 EX31_RS14785 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 0.71 EX31_RS13655 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 89
Pantoea sp. MT58 0.86 IAI47_01585 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 0.71 IAI47_04500 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 76
Serratia liquefaciens MT49 0.79 IAI46_00980 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF 0.70 IAI46_20000 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA low > 86
Herbaspirillum seropedicae SmR1 0.70 HSERO_RS08290 leucine/isoleucine/valine transporter ATP-binding subunit 0.40 HSERO_RS13570 hemolysin D low > 78
Pseudomonas syringae pv. syringae B728a ΔmexB 0.68 Psyr_3849 L-isoleucine ABC transporter ATP-binding protein / L-leucine ABC transporter ATP-binding protein / L-valine ABC transporter ATP-binding protein 0.42 Psyr_1730 Secretion protein HlyD low > 86
Pseudomonas syringae pv. syringae B728a 0.68 Psyr_3849 L-isoleucine ABC transporter ATP-binding protein / L-leucine ABC transporter ATP-binding protein / L-valine ABC transporter ATP-binding protein 0.42 Psyr_1730 Secretion protein HlyD 0.22 70
Castellaniella sp019104865 MT123 0.66 ABCV34_RS03635 ABC transporter ATP-binding protein 0.39 ABCV34_RS05945 HlyD family efflux transporter periplasmic adaptor subunit low > 48
Cupriavidus basilensis FW507-4G11 0.66 RR42_RS14405 leucine/isoleucine/valine transporter ATP-binding subunit 0.44 RR42_RS12825 hemolysin D low > 128
Pseudomonas putida KT2440 0.64 PP_1137 high-affinity branched-chain amino acid transporter, ATP binding 0.40 PP_3549 multidrug efflux transport system - membrane fusion protein low > 96
Pseudomonas fluorescens FW300-N2C3 0.64 AO356_05340 ABC transporter ATP-binding protein 0.38 AO356_01030 hemolysin D low > 104
Pseudomonas fluorescens SBW25-INTG 0.64 PFLU_RS06625 ABC transporter ATP-binding protein 0.41 PFLU_RS18900 HlyD family efflux transporter periplasmic adaptor subunit low > 109
Pseudomonas simiae WCS417 0.64 PS417_06595 ABC transporter ATP-binding protein 0.40 PS417_16915 hemolysin D — —
Pseudomonas sp. RS175 0.64 PFR28_00536 High-affinity branched-chain amino acid transport ATP-binding protein LivF 0.41 PFR28_02748 Multidrug export protein EmrA low > 88
Pseudomonas fluorescens SBW25 0.64 PFLU_RS06625 ABC transporter ATP-binding protein 0.41 PFLU_RS18900 HlyD family efflux transporter periplasmic adaptor subunit low > 109
Pseudomonas fluorescens GW456-L13 0.64 PfGW456L13_4611 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) 0.39 PfGW456L13_2605 Membrane fusion component of tripartite multidrug resistance system low > 87
Pseudomonas sp. S08-1 0.64 OH686_04625 Branched-chain amino acid ABC transporter, ATP-binding protein LivF 0.18 OH686_04565 Membrane fusion component of MSF-type tripartite multidrug efflux system low > 80
Pseudomonas fluorescens FW300-N1B4 0.63 Pf1N1B4_3214 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) 0.41 Pf1N1B4_4001 Membrane fusion component of tripartite multidrug resistance system low > 87
Pseudomonas fluorescens FW300-N2E3 0.63 AO353_17105 ABC transporter ATP-binding protein 0.40 AO353_27845 hemolysin D low > 101
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_2926 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 2 LivF (from data) 0.41 Pf6N2E2_148 Membrane fusion component of tripartite multidrug resistance system low > 103
Rhodospirillum rubrum S1H 0.60 Rru_A1748 ABC transporter component (NCBI) 0.41 Rru_A0859 Secretion protein HlyD (NCBI) low > 58
Rhodopseudomonas palustris CGA009 0.54 TX73_019725 ABC transporter ATP-binding protein 0.34 TX73_019155 efflux RND transporter periplasmic adaptor subunit low > 86
Variovorax sp. OAS795 0.53 ABID97_RS27565 ABC transporter ATP-binding protein 0.40 ABID97_RS20395 efflux RND transporter periplasmic adaptor subunit low > 91
Paraburkholderia graminis OAS925 0.51 ABIE53_005651 branched-chain amino acid transport system ATP-binding protein 0.45 ABIE53_002457 membrane fusion protein (multidrug efflux system) low > 113
Variovorax sp. SCN45 0.49 GFF2170 Branched-chain amino acid ABC transporter, ATP-binding protein LivF (TC 3.A.1.4.1) 0.40 GFF4770 Multidrug efflux system EmrAB-OMF, membrane fusion component EmrA low > 127
Ralstonia solanacearum GMI1000 0.47 RS_RS17280 ABC transporter ATP-binding protein 0.41 RS_RS06480 hemolysin D low > 80
Ralstonia sp. UNC404CL21Col 0.47 ABZR87_RS00295 ABC transporter ATP-binding protein 0.42 ABZR87_RS11230 HlyD family secretion protein low > 80
Ralstonia solanacearum IBSBF1503 0.47 RALBFv3_RS23185 ABC transporter ATP-binding protein 0.43 RALBFv3_RS15700 hemolysin D low > 76
Ralstonia solanacearum PSI07 0.47 RPSI07_RS00085 ABC transporter ATP-binding protein 0.41 RPSI07_RS17655 hemolysin D low > 81
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF953 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) 0.35 GFF3756 Membrane fusion component of tripartite multidrug resistance system low > 90
Acidovorax sp. GW101-3H11 0.46 Ac3H11_1692 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, ATPase component 2 (from data) 0.40 Ac3H11_2351 Membrane fusion component of tripartite multidrug resistance system low > 79
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS03120 ABC transporter ATP-binding protein 0.47 QEN71_RS23080 EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit low > 153
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_04059 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family 0.45 H281DRAFT_05108 membrane fusion protein, multidrug efflux system low > 103
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS15590 amino acid ABC transporter ATPase 0.46 BPHYT_RS08090 hemolysin D low > 109

Not shown: 20 genomes with orthologs for ECD_03303 only; 15 genomes with orthologs for ECD_02540 only