Conservation of cofitness between CSW01_12610 and CSW01_17095 in Vibrio cholerae E7946 ATCC 55056

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12610 3-isopropylmalate dehydratase small subunit 1.0 CSW01_17095 protein acetyltransferase 0.70 14
Serratia liquefaciens MT49 0.78 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.54 IAI46_20025 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 86
Dickeya dadantii 3937 0.78 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.54 DDA3937_RS16785 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 74
Pectobacterium carotovorum WPP14 0.77 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.54 HER17_RS04430 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.54 HGI48_RS16855 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 71
Dickeya dianthicola ME23 0.76 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.54 DZA65_RS17930 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 75
Klebsiella pneumoniae MKP103 0.75 KDGMDA_12895 3-isopropylmalate dehydratase small subunit 0.52 KDGMDA_28525 protein lysine acetyltransferase low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.74 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.53 GFF2096 Protein acetyltransferase low > 78
Enterobacter asburiae PDN3 0.74 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.54 EX28DRAFT_0063 Acyl-CoA synthetase (NDP forming) low > 76
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS12985 3-isopropylmalate dehydratase small subunit 0.52 PagCFBP13505_RS14470 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 74
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 0.53 OHPLBJKB_01122 Protein lysine acetyltransferase Pka low > 74
Pantoea sp. MT58 0.73 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.52 IAI47_04475 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 76
Klebsiella michiganensis M5al 0.73 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.52 BWI76_RS21400 protein lysine acetyltransferase low > 92
Rahnella sp. WP5 0.73 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.52 EX31_RS13680 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 89
Escherichia coli ECOR27 0.72 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 0.53 NOLOHH_12990 pat protein lysine acetyltransferase low > 76
Escherichia coli BL21 0.72 ECD_00073 3-isopropylmalate dehydratase small subunit 0.53 ECD_02478 protein lysine acetyltransferase low > 61
Escherichia coli ECRC62 0.72 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 0.53 BNILDI_11795 pat protein lysine acetyltransferase low > 75
Escherichia coli BW25113 0.72 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.53 b2584 yfiQ fused predicted acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunit (NCBI) low > 76
Escherichia fergusonii Becca 0.72 EFB2_03974 3-isopropylmalate dehydratase small subunit 0.53 EFB2_01312 Peptidyl-lysine N-acetyltransferase PatZ low > 86
Escherichia coli ECOR38 0.72 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.53 HEPCGN_20445 pat protein lysine acetyltransferase low > 88
Escherichia coli Nissle 1917 0.72 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 0.53 ECOLIN_RS14625 protein lysine acetyltransferase low > 55
Escherichia coli ECRC98 0.72 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 0.53 JDDGAC_24985 pat protein lysine acetyltransferase low > 87
Escherichia coli ECRC100 0.72 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 0.53 OKFHMN_21320 pat protein lysine acetyltransferase low > 79
Escherichia coli ECRC102 0.72 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 0.53 NIAGMN_19090 pat protein lysine acetyltransferase low > 80
Escherichia coli ECRC101 0.72 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 0.53 MCAODC_11850 pat protein lysine acetyltransferase low > 88
Escherichia coli ECRC99 0.72 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 0.53 KEDOAH_06900 pat protein lysine acetyltransferase — —
Enterobacter sp. TBS_079 0.71 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.54 MPMX20_03453 Peptidyl-lysine N-acetyltransferase Pat low > 85
Shewanella loihica PV-4 0.65 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.51 Shew_2039 GCN5-related N-acetyltransferase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.65 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.48 SO2116 acetyltransferase, GNAT family (NCBI ptt file) low > 76
Erwinia tracheiphila SCR3 0.65 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.47 LU632_RS16920 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 74
Erwinia tracheiphila HP pepo 2.2 0.65 IJEDHG_06010 leuD 3-isopropylmalate dehydratase small subunit 0.47 IJEDHG_26820 protein acetyltransferase low > 61
Erwinia amylovora T8 0.64 OLJFJH_01300 3-isopropylmalate dehydratase small subunit 0.50 OLJFJH_09780 protein acetyltransferase low > 58
Shewanella sp. ANA-3 0.64 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.48 Shewana3_2223 CoA-binding domain-containing protein (RefSeq) low > 73
Shewanella amazonensis SB2B 0.63 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.49 Sama_1760 acetyltransferase (RefSeq) low > 62
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.30 Xcc-8004.5063.1 Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative low > 74
Marinobacter adhaerens HP15 0.58 HP15_1833 isopropylmalate isomerase small subunit 0.30 HP15_1220 acetyltransferase, GNAT family low > 73
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_06073 3-isopropylmalate dehydratase, small subunit 0.21 H281DRAFT_03536 acetyltransferase low > 103
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS33905 3-isopropylmalate dehydratase small subunit 0.21 BPHYT_RS34265 N-acetyltransferase GCN5 low > 109
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS24180 3-isopropylmalate dehydratase 0.37 RR42_RS09770 GCN5 family acetyltransferase low > 128
Variovorax sp. SCN45 0.55 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.33 GFF7221 Protein lysine acetyltransferase Pat (EC 2.3.1.-) low > 127
Azospirillum sp. SherDot2 0.53 MPMX19_00606 3-isopropylmalate dehydratase small subunit 1 0.37 MPMX19_02746 Peptidyl-lysine N-acetyltransferase Pat low > 112
Dechlorosoma suillum PS 0.53 Dsui_3199 3-isopropylmalate dehydratase, small subunit 0.35 Dsui_2189 acyl-CoA synthetase (NDP forming) — —
Azospirillum brasilense Sp245 0.52 AZOBR_RS14135 isopropylmalate isomerase 0.36 AZOBR_RS01315 GCN5 family N-acetyltransferase low > 97
Magnetospirillum magneticum AMB-1 0.52 AMB_RS20565 3-isopropylmalate dehydratase small subunit 0.41 AMB_RS12870 GNAT family N-acetyltransferase — —
Rhodopseudomonas palustris CGA009 0.51 TX73_001215 3-isopropylmalate dehydratase small subunit 0.31 TX73_021970 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase — —
Rhodospirillum rubrum S1H 0.50 Rru_A1190 3-isopropylmalate dehydratase small subunit region (NCBI) 0.39 Rru_A1804 N-acetyltransferase (NCBI) low > 58
Bosea sp. OAE506 0.50 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit 0.23 ABIE41_RS01525 GNAT family N-acetyltransferase — —
Sinorhizobium meliloti 1021 0.49 SMc03795 isopropylmalate isomerase small subunit 0.28 SMa1146 hypothetical protein low > 103
Xanthobacter sp. DMC5 0.47 GFF1843 3-isopropylmalate dehydratase small subunit 1 0.34 GFF3779 Peptidyl-lysine N-acetyltransferase PatZ — —
Sphingomonas koreensis DSMZ 15582 0.38 Ga0059261_4225 3-isopropylmalate dehydratase, small subunit 0.29 Ga0059261_3832 Acyl-CoA synthetase (NDP forming) low > 68
Lysobacter sp. OAE881 0.37 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit 0.30 ABIE51_RS08475 bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase low > 62

Not shown: 64 genomes with orthologs for CSW01_12610 only; 2 genomes with orthologs for CSW01_17095 only