| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_05290 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 1.0 | CSW01_13525 | | DNA-binding transcriptional regulator CytR | 0.67 | 5 |
| Escherichia coli ECOR27 | 0.72 | NOLOHH_20290 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | NOLOHH_05870 | cytR | DNA-binding transcriptional regulator CytR | low | > 76 |
| Escherichia coli ECRC62 | 0.72 | BNILDI_18440 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | BNILDI_05660 | cytR | DNA-binding transcriptional regulator CytR | low | > 75 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.72 | OHPLBJKB_02414 | | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | OHPLBJKB_04117 | | HTH-type transcriptional repressor CytR | low | > 74 |
| Escherichia coli Nissle 1917 | 0.72 | ECOLIN_RS07640 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | ECOLIN_RS22650 | | DNA-binding transcriptional regulator CytR | low | > 55 |
| Escherichia fergusonii Becca | 0.72 | EFB2_02657 | | Corrinoid adenosyltransferase | 0.67 | EFB2_04684 | | HTH-type transcriptional repressor CytR | low | > 86 |
| Escherichia coli BW25113 | 0.72 | b1270 | btuR | cob(I)yrinic acid a,c-diamide adenosyltransferase (NCBI) | 0.67 | b3934 | cytR | DNA-binding transcriptional dual regulator (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.72 | ECD_01246 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | ECD_03819 | | Anti-activator for CytR-CRP nucleoside utilization regulon | low | > 61 |
| Escherichia coli ECOR38 | 0.71 | HEPCGN_25575 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | HEPCGN_12370 | cytR | DNA-binding transcriptional regulator CytR | low | > 88 |
| Escherichia coli ECRC98 | 0.71 | JDDGAC_05170 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | JDDGAC_17350 | cytR | DNA-binding transcriptional regulator CytR | low | > 87 |
| Escherichia coli ECRC102 | 0.71 | NIAGMN_26795 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | NIAGMN_11480 | cytR | DNA-binding transcriptional regulator CytR | low | > 80 |
| Escherichia coli ECRC99 | 0.71 | KEDOAH_26140 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | KEDOAH_14435 | cytR | DNA-binding transcriptional regulator CytR | — | — |
| Escherichia coli ECRC101 | 0.71 | MCAODC_15640 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | MCAODC_04225 | cytR | DNA-binding transcriptional regulator CytR | low | > 88 |
| Escherichia coli ECRC100 | 0.71 | OKFHMN_02625 | cobO | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.67 | OKFHMN_13725 | cytR | DNA-binding transcriptional regulator CytR | low | > 79 |
| Rahnella sp. WP5 | 0.70 | EX31_RS09915 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.70 | EX31_RS14230 | | DNA-binding transcriptional regulator CytR | low | > 89 |
| Klebsiella michiganensis M5al | 0.70 | BWI76_RS11900 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.68 | BWI76_RS00765 | | DNA-binding transcriptional regulator CytR | low | > 92 |
| Pectobacterium carotovorum WPP14 | 0.70 | HER17_RS10895 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.66 | HER17_RS00865 | | DNA-binding transcriptional regulator CytR | low | > 75 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.69 | GFF2718 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | 0.66 | GFF2316 | | Transcriptional (co)regulator CytR | low | > 78 |
| Shewanella amazonensis SB2B | 0.69 | Sama_0766 | | cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) | 0.36 | Sama_0294 | | LacI family transcription regulator (RefSeq) | low | > 62 |
| Pantoea agglomerans CFBP13505 P0401 | 0.69 | PagCFBP13505_RS06970 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.66 | PagCFBP13505_RS18480 | | DNA-binding transcriptional regulator CytR | low | > 74 |
| Pantoea sp. MT58 | 0.69 | IAI47_09215 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.66 | IAI47_00860 | | DNA-binding transcriptional regulator CytR | low | > 76 |
| Shewanella loihica PV-4 | 0.68 | Shew_0718 | | cob(I)yrinic acid a,c-diamide adenosyltransferase (RefSeq) | 0.21 | Shew_1870 | | LacI family transcription regulator (RefSeq) | low | > 60 |
| Enterobacter sp. TBS_079 | 0.68 | MPMX20_02506 | | Corrinoid adenosyltransferase | 0.68 | MPMX20_04535 | | HTH-type transcriptional repressor CytR | low | > 85 |
| Enterobacter asburiae PDN3 | 0.68 | EX28DRAFT_0941 | | cob(I)alamin adenosyltransferase | 0.67 | EX28DRAFT_4407 | | Transcriptional regulators | low | > 76 |
| Serratia liquefaciens MT49 | 0.67 | IAI46_13990 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.69 | IAI46_24560 | | DNA-binding transcriptional regulator CytR | low | > 86 |
| Dickeya dadantii 3937 | 0.67 | DDA3937_RS10505 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.61 | DDA3937_RS00930 | | DNA-binding transcriptional regulator CytR | low | > 74 |
| Dickeya dianthicola 67-19 | 0.67 | HGI48_RS10505 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.61 | HGI48_RS20445 | | DNA-binding transcriptional regulator CytR | low | > 71 |
| Dickeya dianthicola ME23 | 0.67 | DZA65_RS10985 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.61 | DZA65_RS21490 | | DNA-binding transcriptional regulator CytR | low | > 75 |
| Klebsiella pneumoniae MKP103 | 0.63 | KDGMDA_19595 | | cob(I)yrinic acid a c-diamide adenosyltransferase | 0.67 | KDGMDA_09275 | | DNA-binding transcriptional regulator CytR | low | > 95 |
| Cupriavidus basilensis FW507-4G11 | 0.52 | RR42_RS16125 | | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.27 | RR42_RS27820 | | GntR family transcriptional regulator | low | > 128 |
| Pseudomonas sp. DMC3 | 0.51 | GFF2547 | | Corrinoid adenosyltransferase | 0.38 | GFF1074 | | HTH-type transcriptional repressor CytR | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.51 | Pf6N2E2_5737 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | 0.39 | Pf6N2E2_322 | | Transcriptional regulator, LacI family | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.49 | AO356_19135 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.40 | AO356_22285 | | LacI family transcriptional regulator | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.49 | Xcc-8004.1393.1 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | 0.24 | Xcc-8004.1274.1 | | transcriptional regulator lacI family | low | > 74 |
| Pseudomonas sp. RS175 | 0.48 | PFR28_03209 | | Corrinoid adenosyltransferase | 0.40 | PFR28_02584 | | HTH-type transcriptional repressor CytR | low | > 88 |
| Pseudomonas fluorescens FW300-N1B4 | 0.48 | Pf1N1B4_3706 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | 0.38 | Pf1N1B4_4095 | | Transcriptional regulator, LacI family | — | — |
| Lysobacter sp. OAE881 | 0.45 | ABIE51_RS04945 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.26 | ABIE51_RS10155 | | LacI family DNA-binding transcriptional regulator | low | > 62 |
| Dyella japonica UNC79MFTsu3.2 | 0.45 | ABZR86_RS10920 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.47 | ABZR86_RS01690 | | LacI family DNA-binding transcriptional regulator | low | > 74 |
| Sinorhizobium meliloti 1021 | 0.44 | SMc04302 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.38 | SM_b20014 | | transcriptional regulator | — | — |
| Rhodospirillum rubrum S1H | 0.43 | Rru_A3367 | | Cob(I)alamin adenosyltransferase (NCBI) | 0.25 | Rru_A1973 | | Transcriptional Regulator, LacI family (NCBI) | low | > 58 |
| Bosea sp. OAE506 | 0.42 | ABIE41_RS01765 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.24 | ABIE41_RS20550 | | LacI family DNA-binding transcriptional regulator | — | — |
| Phaeobacter inhibens DSM 17395 | 0.42 | PGA1_c08200 | | cob(I)yrinic acid a,c-diamide adenosyltransferase CobO | 0.29 | PGA1_c07800 | | putative transcriptional regulator, lacI family | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.41 | H281DRAFT_06529 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.34 | H281DRAFT_00103 | | transcriptional regulator, LacI family | low | > 103 |
| Rhizobium sp. OAE497 | 0.41 | ABIE40_RS11150 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.33 | ABIE40_RS16795 | | LacI family DNA-binding transcriptional regulator | low | > 107 |
| Paraburkholderia graminis OAS925 | 0.41 | ABIE53_006184 | | cob(I)alamin adenosyltransferase | 0.33 | ABIE53_001217 | | LacI family repressor for deo operon, udp, cdd, tsx, nupC, and nupG | low | > 113 |
| Sphingomonas koreensis DSMZ 15582 | 0.41 | Ga0059261_0621 | | cob(I)yrinic acid a,c-diamide adenosyltransferase (EC 2.5.1.17) | 0.34 | Ga0059261_0555 | | transcriptional regulator, LacI family | low | > 68 |
| Dinoroseobacter shibae DFL-12 | 0.40 | Dshi_0157 | | cob(I)alamin adenosyltransferase (RefSeq) | 0.24 | Dshi_2029 | | transcriptional regulator, LacI family (RefSeq) | — | — |
| Burkholderia phytofirmans PsJN | 0.40 | BPHYT_RS24825 | | cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase | 0.35 | BPHYT_RS04680 | | LacI family transcriptional regulator | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.40 | QEN71_RS08695 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.36 | QEN71_RS25305 | | LacI family DNA-binding transcriptional regulator | low | > 153 |
| Agrobacterium fabrum C58 | 0.37 | Atu2807 | | cob(I)alamin adenosyltransferase | 0.40 | Atu4373 | | LacI family transcriptional regulator | low | > 89 |
| Xanthobacter sp. DMC5 | 0.36 | GFF371 | | Corrinoid adenosyltransferase | 0.26 | GFF4087 | | HTH-type transcriptional repressor CytR | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.34 | GFF3983 | | Cob(I)alamin adenosyltransferase (EC 2.5.1.17) | 0.23 | GFF4454 | | Transcriptional regulator, LacI family | low | > 90 |
| Bacteroides ovatus ATCC 8483 | 0.24 | BACOVA_04737 | | cob(I)yrinic acid a,c-diamide adenosyltransferase | 0.25 | BACOVA_03411 | | sugar-binding domain protein | low | > 96 |
Not shown: 40 genomes with orthologs for CSW01_05290 only; 16 genomes with orthologs for CSW01_13525 only