Conservation of cofitness between CSW01_08760 and CSW01_06380 in Vibrio cholerae E7946 ATCC 55056

58 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_08760 NAD-dependent succinate-semialdehyde dehydrogenase 1.0 CSW01_06380 GTP cyclohydrolase II 0.65 13
Klebsiella michiganensis M5al 0.57 BWI76_RS05620 NAD-dependent succinate-semialdehyde dehydrogenase 0.36 BWI76_RS11945 GTP cyclohydrolase II — —
Pseudomonas sp. S08-1 0.57 OH686_11875 Succinate-semialdehyde dehydrogenase [NAD(P)+] 0.34 OH686_15740 GTP cyclohydrolase II — —
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_0091 succinate semialdehyde dehydrogenase 0.33 Psyr_4456 GTP cyclohydrolase II — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_0091 succinate semialdehyde dehydrogenase 0.33 Psyr_4456 GTP cyclohydrolase II — —
Escherichia coli ECRC99 0.57 KEDOAH_07225 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 KEDOAH_26195 ribA GTP cyclohydrolase-2 — —
Escherichia coli ECRC102 0.57 NIAGMN_18680 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 NIAGMN_26740 ribA GTP cyclohydrolase-2 — —
Pseudomonas sp. RS175 0.57 PFR28_04755 Glutarate-semialdehyde dehydrogenase 0.35 PFR28_03941 Riboflavin biosynthesis protein — —
Escherichia coli ECOR27 0.57 NOLOHH_12740 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 NOLOHH_20235 ribA GTP cyclohydrolase-2 — —
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS21375 succinate-semialdehyde dehydrogenase 0.33 RR42_RS29255 GTP cyclohydrolase low > 128
Escherichia coli ECRC101 0.57 MCAODC_11435 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 MCAODC_15695 ribA GTP cyclohydrolase-2 — —
Escherichia coli ECRC100 0.57 OKFHMN_20915 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 OKFHMN_02570 ribA GTP cyclohydrolase-2 — —
Escherichia coli ECRC98 0.57 JDDGAC_24575 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 JDDGAC_05115 ribA GTP cyclohydrolase-2 — —
Pseudomonas aeruginosa PUPa3 0.57 DQ20_RS38020 gabD;go_function=succinate-semialdehyde NADP-dependent succinate-semialdehyde dehydrogenase 0.35 DQ20_RS47945 ribA;go_function=GTP GTP cyclohydrolase II — —
Pseudomonas fluorescens GW456-L13 0.57 PfGW456L13_495 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) (from data) 0.34 PfGW456L13_1321 GTP cyclohydrolase II (EC 3.5.4.25) — —
Pseudomonas aeruginosa MRSN321 0.57 DY961_RS21260 gabD;go_function=succinate-semialdehyde NADP-dependent succinate-semialdehyde dehydrogenase 0.35 DY961_RS27700 ribA;go_function=GTP GTP cyclohydrolase II — —
Escherichia coli ECOR38 0.57 HEPCGN_20150 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 HEPCGN_25630 ribA GTP cyclohydrolase-2 — —
Escherichia coli BW25113 0.57 b2661 gabD succinate-semialdehyde dehydrogenase I, NADP-dependent (NCBI) 0.37 b1277 ribA GTP cyclohydrolase II protein (NCBI) — —
Escherichia coli ECRC62 0.57 BNILDI_11300 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.37 BNILDI_18385 ribA GTP cyclohydrolase-2 — —
Pseudomonas segetis P6 0.57 MPMX49_00504 Glutarate-semialdehyde dehydrogenase 0.35 MPMX49_00999 Riboflavin biosynthesis protein — —
Escherichia coli BL21 0.57 ECD_02517 succinate-semialdehyde dehydrogenase I, NADP-dependent 0.37 ECD_01254 GTP cyclohydrolase II — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.57 OHPLBJKB_01071 Succinate-semialdehyde dehydrogenase [NADP(+)] GabD 0.37 OHPLBJKB_02405 GTP cyclohydrolase-2 — —
Pseudomonas aeruginosa PA14 0.57 IKLFDK_24135 NADP-dependent succinate-semialdehyde dehydrogenase 0.35 IKLFDK_20865 GTP cyclohydrolase-2 — —
Pseudomonas fluorescens FW300-N2E2 0.57 Pf6N2E2_4014 Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) 0.35 Pf6N2E2_4927 GTP cyclohydrolase II (EC 3.5.4.25) — —
Pseudomonas stutzeri RCH2 0.57 Psest_3654 succinate-semialdehyde dehydrogenase 0.34 Psest_3544 GTP cyclohydrolase II — —
Pseudomonas orientalis W4I3 0.57 QF045_RS03955 NADP-dependent succinate-semialdehyde dehydrogenase 0.35 QF045_RS27195 GTP cyclohydrolase II — —
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_10720 succinate-semialdehyde dehydrogenase 0.35 AO356_14970 GTP cyclohydrolase — —
Pseudomonas fluorescens FW300-N2E3 0.56 AO353_11505 succinate-semialdehyde dehydrogenase (EC 1.2.1.16) (from data) 0.35 AO353_06675 GTP cyclohydrolase — —
Pseudomonas sp. DMC3 0.56 GFF4256 Glutarate-semialdehyde dehydrogenase 0.34 GFF3835 Riboflavin biosynthesis protein — —
Castellaniella sp019104865 MT123 0.56 ABCV34_RS09380 NADP-dependent succinate-semialdehyde dehydrogenase 0.36 ABCV34_RS00955 GTP cyclohydrolase II — —
Shewanella oneidensis MR-1 0.56 SO1275 gabD succinate-semialdehyde dehydrogenase (NADP+) [EC: 1.2.1.16] (from data) 0.37 SO2831 ribA GTP cyclohydrolase II (NCBI ptt file) — —
Shewanella sp. ANA-3 0.56 Shewana3_3092 succinate semialdehyde dehydrogenase (RefSeq) 0.37 Shewana3_2600 ribA GTP cyclohydrolase II (RefSeq) — —
Pseudomonas sp. SVBP6 0.56 COO64_RS12475 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.41 COO64_RS10760 ribA GTP cyclohydrolase II RibA low > 93
Pseudomonas fluorescens FW300-N1B4 0.56 Pf1N1B4_1734 Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) 0.34 Pf1N1B4_2657 GTP cyclohydrolase II (EC 3.5.4.25) — —
Pseudomonas simiae WCS417 0.56 PS417_00895 succinate-semialdehyde dehydrogenase 0.34 PS417_25230 GTP cyclohydrolase — —
Pseudomonas lactucae CFBP13502 0.56 GEMAOFIL_00403 Glutarate-semialdehyde dehydrogenase 0.35 GEMAOFIL_05151 Riboflavin biosynthesis protein — —
Pseudomonas sp. BP01 0.56 JOY50_RS18515 gabD NADP-dependent succinate-semialdehyde dehydrogenase 0.33 JOY50_RS20085 ribA GTP cyclohydrolase II — —
Pseudomonas putida KT2440 0.56 PP_0213 succinate-semialdehyde dehydrogenase (NADP+) 0.33 PP_0522 GTP cyclohydrolase-2 — —
Ralstonia solanacearum UW163 0.55 UW163_RS04040 NAD-dependent succinate-semialdehyde dehydrogenase 0.45 UW163_RS21235 GTP cyclohydrolase II RibA — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS09540 NAD-dependent succinate-semialdehyde dehydrogenase 0.45 RALBFv3_RS17905 GTP cyclohydrolase II RibA low > 76
Klebsiella pneumoniae MKP103 0.55 KDGMDA_13835 NADP-dependent succinate-semialdehyde dehydrogenase 0.36 KDGMDA_19635 GTP cyclohydrolase-2 — —
Pectobacterium carotovorum WPP14 0.55 HER17_RS09885 NAD-dependent succinate-semialdehyde dehydrogenase 0.35 HER17_RS09325 GTP cyclohydrolase II — —
Escherichia coli Nissle 1917 0.55 ECOLIN_RS14840 NADP-dependent succinate-semialdehyde dehydrogenase 0.37 ECOLIN_RS07710 GTP cyclohydrolase II — —
Escherichia fergusonii Becca 0.54 EFB2_01269 Succinate-semialdehyde dehydrogenase [NADP(+)] GabD 0.37 EFB2_02648 GTP cyclohydrolase-2 — —
Serratia liquefaciens MT49 0.54 IAI46_22160 NAD-dependent succinate-semialdehyde dehydrogenase 0.35 IAI46_13945 GTP cyclohydrolase II — —
Dickeya dianthicola 67-19 0.54 HGI48_RS11855 NAD-dependent succinate-semialdehyde dehydrogenase 0.35 HGI48_RS12600 GTP cyclohydrolase II — —
Dickeya dianthicola ME23 0.54 DZA65_RS12400 NAD-dependent succinate-semialdehyde dehydrogenase 0.35 DZA65_RS13050 GTP cyclohydrolase II — —
Acinetobacter baumannii LAC-4 0.54 RR41_RS15005 NAD-dependent succinate-semialdehyde dehydrogenase 0.32 RR41_RS02005 GTP cyclohydrolase II — —
Acinetobacter radioresistens SK82 0.54 MPMX26_01991 Glutarate-semialdehyde dehydrogenase 0.35 MPMX26_02745 GTP cyclohydrolase-2 — —
Dechlorosoma suillum PS 0.54 Dsui_0437 succinate-semialdehyde dehydrogenase 0.36 Dsui_0717 GTP cyclohydrolase II — —
Marinobacter adhaerens HP15 0.53 HP15_2020 succinate-semialdehyde dehydrogenase I 0.38 HP15_579 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein — —
Shewanella amazonensis SB2B 0.53 Sama_2637 succinate-semialdehyde dehydrogenase (NAD(P)(+)) (RefSeq) 0.37 Sama_1277 ribA GTP cyclohydrolase II (RefSeq) — —
Enterobacter asburiae PDN3 0.52 EX28DRAFT_3290 succinate-semialdehyde dehydrogenase 0.36 EX28DRAFT_0950 GTP cyclohydrolase II — —
Pantoea sp. MT58 0.52 IAI47_07580 NAD-dependent succinate-semialdehyde dehydrogenase 0.35 IAI47_09255 GTP cyclohydrolase II — —
Pantoea agglomerans CFBP13505 P0401 0.52 PagCFBP13505_RS01475 NAD-dependent succinate-semialdehyde dehydrogenase 0.35 PagCFBP13505_RS06920 GTP cyclohydrolase II — —
Enterobacter sp. TBS_079 0.51 MPMX20_04145 Glutarate-semialdehyde dehydrogenase 0.36 MPMX20_02498 GTP cyclohydrolase-2 — —
Rahnella sp. WP5 0.50 EX31_RS12300 NAD-dependent succinate-semialdehyde dehydrogenase 0.36 EX31_RS09880 GTP cyclohydrolase II — —
Shewanella loihica PV-4 0.48 Shew_3173 succinic semialdehyde dehydrogenase (RefSeq) 0.37 Shew_2446 GTP cyclohydrolase II (RefSeq) — —
Erwinia tracheiphila SCR3 0.25 LU632_RS10125 NAD-dependent succinate-semialdehyde dehydrogenase 0.37 LU632_RS12530 ribA GTP cyclohydrolase II — —

Not shown: 46 genomes with orthologs for CSW01_08760 only; 5 genomes with orthologs for CSW01_06380 only