Conservation of cofitness between CSW01_11390 and CSW01_01845 in Vibrio cholerae E7946 ATCC 55056

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11390 class I SAM-dependent methyltransferase 1.0 CSW01_01845 protease modulator HflK 0.48 10
Serratia liquefaciens MT49 0.41 IAI46_04140 class I SAM-dependent methyltransferase 0.45 IAI46_01635 FtsH protease activity modulator HflK low > 87
Pantoea agglomerans CFBP13505 P0401 0.39 PagCFBP13505_RS09820 class I SAM-dependent methyltransferase 0.46 PagCFBP13505_RS11195 FtsH protease activity modulator HflK low > 74
Pantoea sp. MT58 0.39 IAI47_15335 class I SAM-dependent methyltransferase 0.47 IAI47_02600 FtsH protease activity modulator HflK low > 76
Pectobacterium carotovorum WPP14 0.39 HER17_RS05460 class I SAM-dependent methyltransferase 0.46 HER17_RS02595 FtsH protease activity modulator HflK low > 75
Dickeya dadantii 3937 0.38 DDA3937_RS16055 class I SAM-dependent methyltransferase 0.48 DDA3937_RS18600 FtsH protease activity modulator HflK low > 74
Dickeya dianthicola 67-19 0.38 HGI48_RS16175 methyltransferase domain-containing protein 0.48 HGI48_RS18535 FtsH protease activity modulator HflK low > 71
Rahnella sp. WP5 0.37 EX31_RS21195 class I SAM-dependent methyltransferase 0.45 EX31_RS08810 FtsH protease activity modulator HflK low > 89
Dickeya dianthicola ME23 0.37 DZA65_RS17260 class I SAM-dependent methyltransferase 0.48 DZA65_RS19670 FtsH protease activity modulator HflK low > 75
Erwinia tracheiphila SCR3 0.37 LU632_RS01085 class I SAM-dependent methyltransferase 0.46 LU632_RS02065 hflK FtsH protease activity modulator HflK low > 73
Enterobacter asburiae PDN3 0.37 EX28DRAFT_2681 Methyltransferase domain 0.48 EX28DRAFT_3371 HflK protein low > 76
Erwinia tracheiphila HP pepo 2.2 0.37 IJEDHG_15385 SAM-dependent methyltransferase 0.46 IJEDHG_06855 hflK FtsH protease activity modulator HflK — —
Enterobacter sp. TBS_079 0.37 MPMX20_00898 hypothetical protein 0.46 MPMX20_00455 Modulator of FtsH protease HflK low > 85
Klebsiella michiganensis M5al 0.37 BWI76_RS05445 type 11 methyltransferase 0.45 BWI76_RS02545 protease modulator HflK low > 92
Klebsiella pneumoniae MKP103 0.37 KDGMDA_13695 SAM-dependent methyltransferase 0.48 KDGMDA_11045 FtsH protease activity modulator HflK low > 95
Escherichia coli BW25113 0.36 b0213 yafS orf, hypothetical protein (VIMSS) 0.48 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) low > 76
Escherichia coli ECOR27 0.36 NOLOHH_02320 yafS Uncharacterized protein YafS 0.48 NOLOHH_04510 hflK FtsH protease activity modulator HflK low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.36 OHPLBJKB_03448 hypothetical protein 0.48 OHPLBJKB_03868 Modulator of FtsH protease HflK low > 74
Escherichia coli ECOR38 0.36 HEPCGN_07915 yafS Uncharacterized protein YafS 0.49 HEPCGN_10475 hflK FtsH protease activity modulator HflK low > 88
Escherichia coli ECRC62 0.36 BNILDI_09350 yafS Uncharacterized protein YafS 0.48 BNILDI_06980 hflK FtsH protease activity modulator HflK low > 75
Escherichia coli BL21 0.36 ECD_00206 putative S-adenosyl-L-methionine-dependent methyltransferase 0.48 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor low > 61
Escherichia fergusonii Becca 0.36 EFB2_03830 hypothetical protein 0.49 EFB2_04361 Modulator of FtsH protease HflK low > 86
Escherichia coli Nissle 1917 0.36 ECOLIN_RS01165 class I SAM-dependent methyltransferase 0.49 ECOLIN_RS24240 FtsH protease activity modulator HflK low > 55
Escherichia coli ECRC100 0.35 OKFHMN_09975 yafS Uncharacterized protein YafS 0.48 OKFHMN_12245 hflK FtsH protease activity modulator HflK low > 79
Escherichia coli ECRC101 0.35 MCAODC_00490 yafS Uncharacterized protein YafS 0.48 MCAODC_02760 hflK FtsH protease activity modulator HflK low > 87
Escherichia coli ECRC98 0.35 JDDGAC_13570 yafS Uncharacterized protein YafS 0.48 JDDGAC_15885 hflK FtsH protease activity modulator HflK low > 87
Escherichia coli ECRC102 0.35 NIAGMN_07825 yafS Uncharacterized protein YafS 0.48 NIAGMN_10095 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC99 0.35 KEDOAH_18180 yafS Uncharacterized protein YafS 0.48 KEDOAH_15910 hflK FtsH protease activity modulator HflK — —
Erwinia amylovora T8 0.35 OLJFJH_18635 SAM-dependent methyltransferase 0.44 OLJFJH_02490 FtsH protease activity modulator HflK low > 58
Shewanella amazonensis SB2B 0.34 Sama_1883 hypothetical protein (RefSeq) 0.47 Sama_3023 hflK protein (RefSeq) low > 62
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.34 GFF4045 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) 0.48 GFF827 HflK protein low > 78
Shewanella sp. ANA-3 0.34 Shewana3_2368 methyltransferase type 11 (RefSeq) 0.51 Shewana3_0599 HflK protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.33 SO2562 conserved hypothetical protein (NCBI ptt file) 0.50 SO0605 hflK hflK protein (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.30 MIT1002_02493 Methyltransferase domain protein 0.48 MIT1002_03786 Modulator of FtsH protease HflK low > 70
Shewanella loihica PV-4 0.30 Shew_2113 hypothetical protein (RefSeq) 0.50 Shew_0568 HflK protein (RefSeq) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.20 GFF4258 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) 0.33 GFF4856 HflK protein low > 90
Variovorax sp. SCN45 0.20 GFF1117 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) 0.33 GFF1002 HflK protein low > 127
Ralstonia sp. UNC404CL21Col 0.20 ABZR87_RS14170 class I SAM-dependent methyltransferase 0.32 ABZR87_RS10950 FtsH protease activity modulator HflK — —
Castellaniella sp019104865 MT123 0.19 ABCV34_RS10480 methyltransferase domain-containing protein 0.33 ABCV34_RS02660 FtsH protease activity modulator HflK — —
Pseudomonas segetis P6 0.19 MPMX49_02809 hypothetical protein 0.36 MPMX49_04151 Modulator of FtsH protease HflK low > 75
Marinobacter adhaerens HP15 0.18 HP15_1804 generic methyl-transferase 0.37 HP15_2497 HflK low > 73
Ralstonia solanacearum UW163 0.17 UW163_RS15530 SAM-dependent methyltransferase 0.33 UW163_RS12775 FtsH protease activity modulator HflK — —
Ralstonia solanacearum IBSBF1503 0.17 RALBFv3_RS02220 SAM-dependent methyltransferase 0.33 RALBFv3_RS15310 FtsH protease activity modulator HflK low > 76
Ralstonia solanacearum PSI07 0.17 RPSI07_RS15225 SAM-dependent methyltransferase 0.34 RPSI07_RS18065 FtsH protease activity modulator HflK low > 81
Cupriavidus basilensis FW507-4G11 0.17 RR42_RS13575 SAM-dependent methyltransferase 0.32 RR42_RS13105 membrane protein — —
Pseudomonas sp. DMC3 0.16 GFF1023 hypothetical protein 0.35 GFF3222 Modulator of FtsH protease HflK low > 89
Pseudomonas simiae WCS417 0.16 PS417_12225 SAM-dependent methyltransferase 0.35 PS417_02500 membrane protein — —
Pseudomonas syringae pv. syringae B728a 0.16 Psyr_1762 conserved hypothetical protein 0.35 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.16 Psyr_1762 conserved hypothetical protein 0.35 Psyr_0574 protease FtsH subunit HflK low > 86
Pseudomonas fluorescens SBW25-INTG 0.16 PFLU_RS12915 methyltransferase domain-containing protein 0.36 PFLU_RS02580 FtsH protease activity modulator HflK 0.68 1
Pseudomonas fluorescens SBW25 0.16 PFLU_RS12915 methyltransferase domain-containing protein 0.36 PFLU_RS02580 FtsH protease activity modulator HflK low > 109
Pseudomonas fluorescens FW300-N2E3 0.16 AO353_23495 SAM-dependent methyltransferase 0.36 AO353_13155 hypothetical protein 0.37 1
Pseudomonas fluorescens FW300-N1B4 0.16 Pf1N1B4_4597 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) 0.37 Pf1N1B4_1410 HflK protein — —
Pseudomonas fluorescens GW456-L13 0.15 PfGW456L13_3339 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) 0.35 PfGW456L13_152 HflK protein 0.31 62
Pseudomonas lactucae CFBP13502 0.15 GEMAOFIL_02690 hypothetical protein 0.35 GEMAOFIL_00738 Modulator of FtsH protease HflK low > 96
Acidovorax sp. GW101-3H11 0.15 Ac3H11_479 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) 0.31 Ac3H11_1801 HflK protein low > 79
Pseudomonas fluorescens FW300-N2E2 0.15 Pf6N2E2_588 FIG005121: SAM-dependent methyltransferase (EC 2.1.1.-) 0.35 Pf6N2E2_3612 HflK protein — —
Pseudomonas sp. RS175 0.15 PFR28_01553 hypothetical protein 0.36 PFR28_05123 Modulator of FtsH protease HflK 0.29 15
Pseudomonas fluorescens FW300-N2C3 0.15 AO356_24485 SAM-dependent methyltransferase 0.36 AO356_08645 hypothetical protein low > 104
Pseudomonas sp. SVBP6 0.14 COO64_RS19255 class I SAM-dependent methyltransferase 0.34 COO64_RS17910 hflK FtsH protease activity modulator HflK low > 93
Kangiella aquimarina DSM 16071 0.13 B158DRAFT_1062 Methylase involved in ubiquinone/menaquinone biosynthesis 0.31 B158DRAFT_1954 protease FtsH subunit HflK low > 40

Not shown: 3 genomes with orthologs for CSW01_11390 only; 28 genomes with orthologs for CSW01_01845 only