Conservation of cofitness between BWI76_RS10700 and BWI76_RS04845 in Klebsiella michiganensis M5al

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS10700 XRE family transcriptional regulator 1.0 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase 0.28 2
Enterobacter asburiae PDN3 0.98 EX28DRAFT_1500 Predicted transcriptional regulators 0.83 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) low > 76
Escherichia coli ECRC62 0.97 BNILDI_18270 puuR HTH-type transcriptional regulator PuuR 0.83 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 75
Escherichia coli ECOR38 0.97 HEPCGN_25765 puuR HTH-type transcriptional regulator PuuR 0.82 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 87
Escherichia coli BW25113 0.97 b1299 puuR DNA-binding transcriptional repressor (NCBI) 0.82 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.97 OHPLBJKB_02383 HTH-type transcriptional regulator PuuR 0.82 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 73
Escherichia coli BL21 0.97 ECD_01276 repressor for the divergent puu operons, putrescine inducible 0.82 ECD_00108 quinolinate phosphoribosyltransferase low > 61
Escherichia coli ECOR27 0.97 NOLOHH_20120 puuR HTH-type transcriptional regulator PuuR 0.82 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 75
Escherichia coli ECRC100 0.97 OKFHMN_02435 puuR HTH-type transcriptional regulator PuuR 0.83 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 80
Escherichia coli ECRC98 0.97 JDDGAC_04980 puuR HTH-type transcriptional regulator PuuR 0.83 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 86
Escherichia coli ECRC102 0.97 NIAGMN_26605 puuR HTH-type transcriptional regulator PuuR 0.83 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase — —
Escherichia coli ECRC99 0.97 KEDOAH_26340 puuR HTH-type transcriptional regulator PuuR 0.83 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase — —
Escherichia coli ECRC101 0.97 MCAODC_15835 puuR HTH-type transcriptional regulator PuuR 0.83 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 87
Serratia liquefaciens MT49 0.89 IAI46_10550 HTH-type transcriptional regulator PuuR 0.72 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase low > 86
Rahnella sp. WP5 0.80 EX31_RS17905 HTH-type transcriptional regulator PuuR 0.74 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase low > 89
Pantoea sp. MT58 0.74 IAI47_07115 HTH-type transcriptional regulator PuuR 0.70 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase low > 76
Pseudomonas stutzeri RCH2 0.41 Psest_3791 Predicted transcriptional regulators 0.52 Psest_0718 nicotinate-nucleotide pyrophosphorylase low > 67
Shewanella sp. ANA-3 0.39 Shewana3_3100 XRE family transcriptional regulator (RefSeq) 0.56 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) — —
Shewanella loihica PV-4 0.39 Shew_0970 XRE family transcriptional regulator (RefSeq) 0.56 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.38 AO353_09140 XRE family transcriptional regulator 0.49 AO353_05520 nicotinate-nucleotide pyrophosphorylase low > 101
Pseudomonas sp. RS175 0.38 PFR28_04396 HTH-type transcriptional regulator PuuR 0.49 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 88
Pseudomonas sp. S08-1 0.38 OH686_13700 Putrescine utilization regulator 0.47 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) low > 80
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_815 Putrescine utilization regulator 0.47 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 87
Pseudomonas putida KT2440 0.37 PP_5268 DNA-binding transcriptional repressor PuuR-putrescine 0.49 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer low > 96
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_4394 Putrescine utilization regulator 0.47 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 103
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_12635 XRE family transcriptional regulator 0.48 AO356_07370 nicotinate-nucleotide pyrophosphorylase low > 104
Shewanella amazonensis SB2B 0.37 Sama_2646 XRE family transcriptional regulator (RefSeq) 0.59 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0238 Helix-turn-helix motif protein 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) low > 86
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0238 Helix-turn-helix motif protein 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) low > 86
Pseudomonas fluorescens SBW25 0.36 PFLU_RS29365 cupin domain-containing protein 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase low > 109
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_2147 Putrescine utilization regulator 0.48 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 87
Pseudomonas simiae WCS417 0.36 PS417_27690 XRE family transcriptional regulator 0.48 PS417_03925 nicotinate-nucleotide pyrophosphorylase low > 88
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS29365 cupin domain-containing protein 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase low > 109
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS23170 XRE family transcriptional regulator 0.42 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase low > 109
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS12920 cupin domain-containing protein 0.42 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase low > 153
Azospirillum sp. SherDot2 0.32 MPMX19_04921 HTH-type transcriptional regulator PuuR 0.32 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Bosea sp. OAE506 0.32 ABIE41_RS05345 cupin domain-containing protein 0.35 ABIE41_RS02500 carboxylating nicotinate-nucleotide diphosphorylase low > 77
Rhodospirillum rubrum S1H 0.30 Rru_A2042 Transcriptional Regulator, XRE family with Cupin sensor domain (NCBI) 0.35 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) low > 58
Sinorhizobium meliloti 1021 0.29 SMc04387 aldehyde dehydrogenase 0.27 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein low > 103
Agrobacterium fabrum C58 0.28 Atu3328 aldehyde dehydrogenase 0.33 Atu4096 nicotinate-nucleotide pyrophosphorylase low > 89
Cupriavidus basilensis FW507-4G11 0.21 RR42_RS00225 XRE family transcriptional regulator 0.41 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase low > 128
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_03130 transcriptional regulator, XRE family with cupin sensor 0.42 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 103
Paraburkholderia graminis OAS925 0.19 ABIE53_004168 transcriptional regulator with XRE-family HTH domain 0.43 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) low > 113
Fusobacterium nucleatum SB010 0.18 HUW76_01135 cupin domain-containing protein 0.31 HUW76_10730 carboxylating nicotinate-nucleotide diphosphorylase low > 35
Vibrio cholerae E7946 ATCC 55056 0.16 CSW01_15345 XRE family transcriptional regulator 0.59 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase low > 62
Ralstonia solanacearum GMI1000 0.16 RS_RS05775 XRE family transcriptional regulator 0.40 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) low > 80
Ralstonia solanacearum IBSBF1503 0.15 RALBFv3_RS14960 XRE family transcriptional regulator 0.42 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) low > 76
Ralstonia solanacearum UW163 0.15 UW163_RS12430 XRE family transcriptional regulator 0.42 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Desulfovibrio vulgaris Hildenborough JW710 0.15 DVU3066 DNA-binding protein (TIGR) 0.29 DVU1807 nadC nicotinate-nucleotide pyrophosphorylase (TIGR) — —
Ralstonia solanacearum PSI07 0.14 RPSI07_RS18415 XRE family transcriptional regulator 0.43 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) low > 81
Variovorax sp. OAS795 0.14 ABID97_RS13245 XRE family transcriptional regulator 0.37 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase low > 91

Not shown: 3 genomes with orthologs for BWI76_RS10700 only; 48 genomes with orthologs for BWI76_RS04845 only