Conservation of cofitness between Atu0205 and Atu1074 in Agrobacterium fabrum C58

45 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu0205 methylmalonate-semialdehyde dehydrogenase 1.0 Atu1074 NAD/NADP dependent oxidoreductase 0.36 12
Rhizobium sp. OAE497 0.88 ABIE40_RS03335 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.83 ABIE40_RS06265 SDR family NAD(P)-dependent oxidoreductase low > 107
Sinorhizobium meliloti 1021 0.84 SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) 0.81 SMc00553 oxidoreductase — —
Rhodopseudomonas palustris CGA009 0.72 TX73_017860 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.51 TX73_015995 SDR family NAD(P)-dependent oxidoreductase — —
Bosea sp. OAE506 0.71 ABIE41_RS23920 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.54 ABIE41_RS17815 SDR family NAD(P)-dependent oxidoreductase low > 77
Azospirillum sp. SherDot2 0.71 MPMX19_05423 Putative 3-oxopropanoate dehydrogenase 0.44 MPMX19_00907 putative oxidoreductase YciK low > 112
Rhodospirillum rubrum S1H 0.66 Rru_A2071 Methylmalonate-semialdehyde dehydrogenase (NCBI) 0.51 Rru_A0403 Short-chain dehydrogenase/reductase SDR (NCBI) — —
Dinoroseobacter shibae DFL-12 0.66 Dshi_1747 methylmalonate-semialdehyde dehydrogenase (RefSeq) 0.35 Dshi_2135 short-chain dehydrogenase/reductase SDR (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.65 PGA1_c17300 methylmalonate-semialdehyde dehydrogenase 0.27 PGA1_c10780 putative short chain dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.63 A4249_RS03580 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.49 A4249_RS03730 SDR family NAD(P)-dependent oxidoreductase low > 48
Sphingomonas koreensis DSMZ 15582 0.62 Ga0059261_3677 methylmalonic acid semialdehyde dehydrogenase 0.39 Ga0059261_3625 Short-chain dehydrogenases of various substrate specificities low > 68
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02357 methylmalonic acid semialdehyde dehydrogenase 0.48 CCNA_01728 short chain dehydrogenase low > 67
Caulobacter crescentus NA1000 0.61 CCNA_02357 methylmalonic acid semialdehyde dehydrogenase 0.48 CCNA_01728 short chain dehydrogenase low > 66
Alteromonas macleodii MIT1002 0.60 MIT1002_03326 Methylmalonate-semialdehyde dehydrogenase [acylating] 0.29 MIT1002_01965 putative oxidoreductase YciK low > 70
Shewanella loihica PV-4 0.59 Shew_0965 methylmalonate-semialdehyde dehydrogenase (RefSeq) 0.31 Shew_2409 short chain dehydrogenase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.59 Sama_2650 methylmalonate-semialdehyde dehydrogenase (RefSeq) 0.30 Sama_2121 short chain dehydrogenase (RefSeq) low > 62
Shewanella sp. ANA-3 0.57 Shewana3_3107 methylmalonate-semialdehyde dehydrogenase [acylating] (RefSeq) 0.28 Shewana3_1528 short chain dehydrogenase (RefSeq) low > 73
Pseudomonas stutzeri RCH2 0.56 Psest_3781 methylmalonic acid semialdehyde dehydrogenase 0.29 Psest_2000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) low > 67
Pseudomonas syringae pv. syringae B728a 0.56 Psyr_0679 methylmalonate-semialdehyde dehydrogenase (acylating) 0.28 Psyr_3652 Short-chain dehydrogenase/reductase SDR low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.56 Psyr_0679 methylmalonate-semialdehyde dehydrogenase (acylating) 0.28 Psyr_3652 Short-chain dehydrogenase/reductase SDR low > 86
Pseudomonas fluorescens SBW25 0.55 PFLU_RS03330 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.28 PFLU_RS08060 YciK family oxidoreductase low > 109
Pseudomonas fluorescens SBW25-INTG 0.55 PFLU_RS03330 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.28 PFLU_RS08060 YciK family oxidoreductase low > 109
Pseudomonas putida KT2440 0.55 PP_0597 methylmalonate-semialdehyde dehydrogenase 0.29 PP_1763 putative oxidoreductase low > 96
Pseudomonas fluorescens FW300-N1B4 0.55 Pf1N1B4_1238 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.29 Pf1N1B4_358 Oxidoreductase, short chain dehydrogenase/reductase family low > 87
Pseudomonas simiae WCS417 0.55 PS417_03250 methylmalonate-semialdehyde dehydrogenase 0.28 PS417_08090 3-oxoacyl-ACP reductase low > 88
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_06080 methylmalonate-semialdehyde dehydrogenase 0.29 AO353_02105 3-oxoacyl-ACP reductase — —
Pseudomonas fluorescens GW456-L13 0.55 PfGW456L13_2 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.29 PfGW456L13_2169 Oxidoreductase, short chain dehydrogenase/reductase family low > 87
Dickeya dadantii 3937 0.55 DDA3937_RS03670 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.27 DDA3937_RS10510 YciK family oxidoreductase low > 74
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_3462 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.27 Pf6N2E2_2527 Oxidoreductase, short chain dehydrogenase/reductase family low > 103
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_07950 methylmalonate-semialdehyde dehydrogenase 0.27 AO356_03500 3-oxoacyl-ACP reductase low > 104
Pseudomonas sp. RS175 0.54 PFR28_05263 Putative 3-oxopropanoate dehydrogenase 0.27 PFR28_00899 putative oxidoreductase YciK — —
Dickeya dianthicola ME23 0.54 DZA65_RS03855 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.26 DZA65_RS10990 YciK family oxidoreductase low > 75
Dickeya dianthicola 67-19 0.54 HGI48_RS03730 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.27 HGI48_RS10510 YciK family oxidoreductase low > 71
Azospirillum brasilense Sp245 0.54 AZOBR_RS22500 methylmalonate-semialdehyde dehydrogenase 0.47 AZOBR_RS08305 oxidoreductase low > 97
Enterobacter sp. TBS_079 0.54 MPMX20_03375 Putative 3-oxopropanoate dehydrogenase 0.27 MPMX20_02505 putative oxidoreductase YciK low > 85
Pseudomonas sp. S08-1 0.53 OH686_07305 methylmalonate-semialdehyde dehydrogenase (acylating) 0.28 OH686_20835 Oxidoreductase, short-chain dehydrogenase/reductase family low > 80
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.53 GFF888 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) 0.27 GFF2717 YciK-like oxidoreductase low > 78
Enterobacter asburiae PDN3 0.53 EX28DRAFT_0147 methylmalonic acid semialdehyde dehydrogenase 0.28 EX28DRAFT_0942 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) low > 76
Pectobacterium carotovorum WPP14 0.53 HER17_RS14440 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.27 HER17_RS10890 YciK family oxidoreductase low > 75
Serratia liquefaciens MT49 0.51 IAI46_24020 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.26 IAI46_13985 YciK family oxidoreductase low > 86
Marinobacter adhaerens HP15 0.51 HP15_2655 methylmalonate-semialdehyde dehydrogenase 0.30 HP15_1225 oxidoreductase, short chain dehydrogenase/reductase family low > 73
Klebsiella michiganensis M5al 0.50 BWI76_RS03070 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) (from data) 0.27 BWI76_RS11905 NAD(P)-dependent oxidoreductase — —
Pantoea sp. MT58 0.50 IAI47_01465 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.30 IAI47_09220 YciK family oxidoreductase low > 76
Erwinia tracheiphila SCR3 0.50 LU632_RS02350 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.25 LU632_RS12725 YciK family oxidoreductase low > 74
Acinetobacter radioresistens SK82 0.46 MPMX26_01550 Methylmalonate-semialdehyde dehydrogenase [acylating] 0.31 MPMX26_00032 putative oxidoreductase YciK — —
Shewanella oneidensis MR-1 0.44 SO1678 mmsA methylmalonate-semialdehyde dehydrogenase (NCBI ptt file) 0.29 SO2935 oxidoreductase, short-chain dehydrogenase/reductase family (NCBI ptt file) low > 76

Not shown: 18 genomes with orthologs for Atu0205 only; 19 genomes with orthologs for Atu1074 only