Conservation of cofitness between A4249_RS11115 and A4249_RS15715 in Brevundimonas sp. GW460-12-10-14-LB2

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS11115 MFS transporter 1.0 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.62 11
Caulobacter crescentus NA1000 0.48 CCNA_01099 tetracycline resistance protein 0.79 CCNA_02109 thiamine biosynthesis protein thiC low > 66
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_01099 tetracycline resistance protein 0.79 CCNA_02109 thiamine biosynthesis protein thiC low > 67
Rhodanobacter sp. FW510-T8 0.21 OKGIIK_12840 Tetracycline resistance MFS efflux pump 0.63 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC low > 52
Rhodopseudomonas palustris CGA009 0.20 TX73_016005 tetracycline resistance MFS efflux pump 0.67 TX73_018540 phosphomethylpyrimidine synthase ThiC low > 86
Azospirillum sp. SherDot2 0.19 MPMX19_06037 Tetracycline resistance protein, class C 0.65 MPMX19_00336 Phosphomethylpyrimidine synthase low > 112
Variovorax sp. SCN45 0.19 GFF5038 Tetracycline resistance, MFS efflux pump => Tet(C) 0.64 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) low > 127
Lysobacter sp. OAE881 0.19 ABIE51_RS01325 TCR/Tet family MFS transporter 0.62 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC low > 62
Pedobacter sp. GW460-11-11-14-LB5 0.19 CA265_RS09445 tetracycline resistance MFS efflux pump 0.63 CA265_RS20165 phosphomethylpyrimidine synthase ThiC low > 88
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0862 Arabinose efflux permease 0.66 Ga0059261_2424 hydroxymethylpyrimidine synthase low > 68
Ralstonia sp. UNC404CL21Col 0.18 ABZR87_RS00595 Tet(A)/Tet(B)/Tet(C) family tetracycline efflux MFS transporter 0.60 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC low > 80
Mucilaginibacter yixingensis YX-36 DSM 26809 0.18 ABZR88_RS10715 TCR/Tet family MFS transporter 0.63 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC low > 71
Escherichia coli ECOR38 0.17 HEPCGN_10845 tet(B tetracycline efflux MFS transporter Tet(B) 0.62 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC low > 87
Escherichia coli ECRC62 0.17 BNILDI_09400 tet(B tetracycline efflux MFS transporter Tet(B) 0.62 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC low > 75
Xanthomonas campestris pv. campestris strain 8004 0.17 Xcc-8004.5290.1 Tetracycline-efflux transporter 0.62 Xcc-8004.1066.1 hypothetical protein low > 74
Sinorhizobium meliloti 1021 0.16 SMc01212 transport transmembrane protein 0.71 SM_b20615 thiamine biosynthesis protein ThiC low > 103
Agrobacterium fabrum C58 0.16 Atu4206 tetracycline resistance protein 0.70 Atu2569 thiamine biosynthesis protein low > 89
Dinoroseobacter shibae DFL-12 0.16 Dshi_1006 major facilitator superfamily MFS_1 (RefSeq) 0.70 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.16 PGA1_c13030 putative tetracycline resistance protein, class C 0.70 PGA1_c09110 thiamine biosynthesis protein ThiC low > 62
Echinicola vietnamensis KMM 6221, DSM 17526 0.14 Echvi_3171 Arabinose efflux permease 0.63 Echvi_3567 thiamine biosynthesis protein ThiC low > 79
Burkholderia phytofirmans PsJN 0.12 BPHYT_RS33385 major facilitator superfamily protein 0.62 BPHYT_RS13220 phosphomethylpyrimidine synthase low > 109
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.12 GFF2532 12-TMS multidrug efflux protein homolog 0.62 GFF4198 Thiamin biosynthesis protein ThiC low > 78
Pseudomonas syringae pv. syringae B728a 0.11 Psyr_1706 General substrate transporter:Major facilitator superfamily 0.62 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.11 Psyr_1706 General substrate transporter:Major facilitator superfamily 0.62 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Ralstonia solanacearum IBSBF1503 0.10 RALBFv3_RS03495 MFS transporter 0.60 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC low > 76
Ralstonia solanacearum UW163 0.10 UW163_RS10175 MFS transporter 0.60 UW163_RS03640 phosphomethylpyrimidine synthase ThiC — —
Paraburkholderia bryophila 376MFSha3.1 0.10 H281DRAFT_03065 MFS transporter, DHA1 family, multidrug resistance protein 0.62 H281DRAFT_00395 hydroxymethylpyrimidine synthase low > 103
Paraburkholderia sabiae LMG 24235 0.10 QEN71_RS32345 MFS transporter 0.62 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC low > 153
Pantoea sp. MT58 0.10 IAI47_17590 MFS transporter 0.62 IAI47_18085 phosphomethylpyrimidine synthase ThiC low > 76
Serratia liquefaciens MT49 0.10 IAI46_12000 multidrug efflux MFS transporter 0.62 IAI46_01320 phosphomethylpyrimidine synthase ThiC low > 86
Ralstonia solanacearum GMI1000 0.10 RS_RS19260 MFS transporter 0.60 RS_RS00555 phosphomethylpyrimidine synthase low > 80
Paraburkholderia graminis OAS925 0.09 ABIE53_000733 MFS family permease 0.62 ABIE53_002857 phosphomethylpyrimidine synthase low > 113
Rahnella sp. WP5 0.09 EX31_RS23770 multidrug efflux MFS transporter 0.63 EX31_RS16815 phosphomethylpyrimidine synthase ThiC low > 89
Azospirillum brasilense Sp245 0.09 AZOBR_RS13080 putative MFS superfamily multidrug transport protein 0.67 AZOBR_RS07940 phosphomethylpyrimidine synthase low > 97
Pectobacterium carotovorum WPP14 0.09 HER17_RS16995 multidrug efflux MFS transporter 0.62 HER17_RS20380 phosphomethylpyrimidine synthase ThiC low > 75
Klebsiella michiganensis M5al 0.08 BWI76_RS06135 MFS transporter 0.62 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC low > 92
Enterobacter asburiae PDN3 0.08 EX28DRAFT_2590 Arabinose efflux permease 0.62 EX28DRAFT_4536 phosphomethylpyrimidine synthase low > 76
Enterobacter sp. TBS_079 0.08 MPMX20_00971 Staphyloferrin B transporter 0.62 MPMX20_00217 Phosphomethylpyrimidine synthase low > 85
Dickeya dadantii 3937 0.08 DDA3937_RS05575 MFS transporter 0.63 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC low > 74
Erwinia tracheiphila SCR3 0.08 LU632_RS18400 MFS transporter 0.62 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC low > 74
Dickeya dianthicola 67-19 0.08 HGI48_RS04590 multidrug efflux MFS transporter 0.62 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC low > 71
Escherichia fergusonii Becca 0.07 EFB2_02921 Staphyloferrin B transporter 0.62 EFB2_04617 Phosphomethylpyrimidine synthase low > 86
Escherichia coli Nissle 1917 0.07 ECOLIN_RS06115 multidrug efflux MFS transporter MdtG 0.62 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC — —
Escherichia coli BW25113 0.07 b1053 mdtG predicted drug efflux system (NCBI) 0.62 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) low > 76
Escherichia coli BL21 0.07 ECD_01049 putative drug efflux system protein 0.62 ECD_03871 phosphomethylpyrimidine synthase low > 61
Escherichia coli ECOR27 0.07 NOLOHH_21305 mdtG multidrug efflux MFS transporter MdtG 0.62 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.07 OHPLBJKB_02612 Multidrug resistance protein MdtG 0.62 OHPLBJKB_04056 Phosphomethylpyrimidine synthase low > 73
Dickeya dianthicola ME23 0.07 DZA65_RS05960 MFS transporter 0.61 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC low > 75
Bacteroides thetaiotaomicron VPI-5482 0.07 BT1670 putative transmembrane transport protein (NCBI ptt file) 0.55 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.07 BACOVA_04412 transporter, major facilitator family protein 0.55 BACOVA_02358 thiamine biosynthesis protein ThiC 0.47 5

Not shown: 8 genomes with orthologs for A4249_RS11115 only; 44 genomes with orthologs for A4249_RS15715 only