Conservation of cofitness between A4249_RS11115 and A4249_RS14305 in Brevundimonas sp. GW460-12-10-14-LB2

47 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS11115 MFS transporter 1.0 A4249_RS14305 gamma-glutamyltransferase family protein 0.63 10
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_01099 tetracycline resistance protein 0.56 CCNA_00565 gamma-glutamyltranspeptidase low > 67
Caulobacter crescentus NA1000 0.48 CCNA_01099 tetracycline resistance protein 0.56 CCNA_00565 gamma-glutamyltranspeptidase low > 66
Rhodanobacter denitrificans MT42 0.21 LRK55_RS10740 tetracycline resistance MFS efflux pump 0.18 LRK55_RS13100 gamma-glutamyltransferase low > 63
Rhodanobacter denitrificans FW104-10B01 0.21 LRK54_RS11035 tetracycline resistance MFS efflux pump 0.18 LRK54_RS13360 gamma-glutamyltransferase low > 59
Rhodanobacter sp. FW510-T8 0.21 OKGIIK_12840 Tetracycline resistance MFS efflux pump 0.18 OKGIIK_02600 ggt gamma-glutamyltransferase low > 52
Rhodopseudomonas palustris CGA009 0.20 TX73_016005 tetracycline resistance MFS efflux pump 0.20 TX73_000130 gamma-glutamyltransferase low > 86
Azospirillum sp. SherDot2 0.19 MPMX19_06037 Tetracycline resistance protein, class C 0.22 MPMX19_05752 Glutathione hydrolase proenzyme low > 112
Rhizobium sp. OAE497 0.19 ABIE40_RS06610 TCR/Tet family MFS transporter 0.17 ABIE40_RS16090 gamma-glutamyltransferase low > 107
Variovorax sp. SCN45 0.19 GFF5038 Tetracycline resistance, MFS efflux pump => Tet(C) 0.18 GFF3077 Gamma-glutamyltranspeptidase (EC 2.3.2.2) @ Glutathione hydrolase (EC 3.4.19.13) low > 127
Lysobacter sp. OAE881 0.19 ABIE51_RS01325 TCR/Tet family MFS transporter 0.20 ABIE51_RS15105 gamma-glutamyltransferase low > 62
Pedobacter sp. GW460-11-11-14-LB5 0.19 CA265_RS09445 tetracycline resistance MFS efflux pump 0.21 CA265_RS17620 gamma-glutamyltransferase low > 88
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0862 Arabinose efflux permease 0.49 Ga0059261_3349 Gamma-glutamyltransferase low > 68
Ralstonia sp. UNC404CL21Col 0.18 ABZR87_RS00595 Tet(A)/Tet(B)/Tet(C) family tetracycline efflux MFS transporter 0.19 ABZR87_RS19795 gamma-glutamyltransferase low > 80
Escherichia coli ECOR38 0.17 HEPCGN_10845 tet(B tetracycline efflux MFS transporter Tet(B) 0.20 HEPCGN_15620 ggt gamma-glutamyltransferase low > 87
Escherichia coli ECRC62 0.17 BNILDI_09400 tet(B tetracycline efflux MFS transporter Tet(B) 0.20 BNILDI_02915 ggt gamma-glutamyltransferase low > 75
Xanthomonas campestris pv. campestris strain 8004 0.17 Xcc-8004.5290.1 Tetracycline-efflux transporter 0.17 Xcc-8004.2158.1 Gamma-glutamyltranspeptidase (EC 2.3.2.2) low > 74
Sinorhizobium meliloti 1021 0.16 SMc01212 transport transmembrane protein 0.18 SM_b20585 gamma-glutamyltranspeptidase low > 103
Agrobacterium fabrum C58 0.16 Atu4206 tetracycline resistance protein 0.38 Atu5507 gamma-glutamyltranspeptidase low > 89
Phaeobacter inhibens DSM 17395 0.16 PGA1_c13030 putative tetracycline resistance protein, class C 0.35 PGA1_c28250 gamma-glutamyltranspeptidase Ggt low > 62
Dinoroseobacter shibae DFL-12 0.16 Dshi_1006 major facilitator superfamily MFS_1 (RefSeq) 0.36 Dshi_0675 gamma-glutamyltransferase (RefSeq) low > 64
Echinicola vietnamensis KMM 6221, DSM 17526 0.14 Echvi_3171 Arabinose efflux permease 0.20 Echvi_3948 gamma-glutamyltranspeptidase low > 79
Burkholderia phytofirmans PsJN 0.12 BPHYT_RS33385 major facilitator superfamily protein 0.21 BPHYT_RS21360 gamma-glutamyltranspeptidase low > 109
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.12 GFF2532 12-TMS multidrug efflux protein homolog 0.20 GFF561 Gamma-glutamyltranspeptidase (EC 2.3.2.2) low > 78
Pseudomonas syringae pv. syringae B728a 0.11 Psyr_1706 General substrate transporter:Major facilitator superfamily 0.19 Psyr_0691 gamma-glutamyltransferase 1, Threonine peptidase, MEROPS family T03 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.11 Psyr_1706 General substrate transporter:Major facilitator superfamily 0.19 Psyr_0691 gamma-glutamyltransferase 1, Threonine peptidase, MEROPS family T03 low > 86
Ralstonia solanacearum UW163 0.10 UW163_RS10175 MFS transporter 0.33 UW163_RS06945 gamma-glutamyltransferase family protein
Ralstonia solanacearum IBSBF1503 0.10 RALBFv3_RS03495 MFS transporter 0.33 RALBFv3_RS06680 gamma-glutamyltransferase family protein low > 76
Paraburkholderia bryophila 376MFSha3.1 0.10 H281DRAFT_03065 MFS transporter, DHA1 family, multidrug resistance protein 0.20 H281DRAFT_01608 gamma-glutamyltransferase 1 Threonine peptidase. MEROPS family T03 low > 103
Paraburkholderia sabiae LMG 24235 0.10 QEN71_RS32345 MFS transporter 0.19 QEN71_RS14675 gamma-glutamyltransferase low > 153
Pantoea sp. MT58 0.10 IAI47_17590 MFS transporter 0.21 IAI47_01620 gamma-glutamyltransferase low > 76
Serratia liquefaciens MT49 0.10 IAI46_12000 multidrug efflux MFS transporter 0.18 IAI46_12745 gamma-glutamyltransferase low > 86
Ralstonia solanacearum GMI1000 0.10 RS_RS19260 MFS transporter 0.30 RS_RS14630 gamma-glutamyltransferase family protein low > 80
Paraburkholderia graminis OAS925 0.09 ABIE53_000733 MFS family permease 0.20 ABIE53_004289 gamma-glutamyltranspeptidase/glutathione hydrolase low > 113
Azospirillum brasilense Sp245 0.09 AZOBR_RS13080 putative MFS superfamily multidrug transport protein 0.36 AZOBR_RS03085 gamma-glutamyltransferase low > 97
Enterobacter asburiae PDN3 0.08 EX28DRAFT_2590 Arabinose efflux permease 0.20 EX28DRAFT_4279 gamma-glutamyltranspeptidase low > 76
Klebsiella michiganensis M5al 0.08 BWI76_RS06135 MFS transporter 0.20 BWI76_RS26275 gamma-glutamyltransferase low > 92
Enterobacter sp. TBS_079 0.08 MPMX20_00971 Staphyloferrin B transporter 0.20 MPMX20_04323 Glutathione hydrolase proenzyme low > 85
Dickeya dadantii 3937 0.08 DDA3937_RS05575 MFS transporter 0.19 DDA3937_RS14030 gamma-glutamyltransferase low > 74
Erwinia tracheiphila SCR3 0.08 LU632_RS18400 MFS transporter 0.21 LU632_RS19180 ggt gamma-glutamyltransferase low > 74
Dickeya dianthicola 67-19 0.08 HGI48_RS04590 multidrug efflux MFS transporter 0.18 HGI48_RS14025 gamma-glutamyltransferase 0.45 47
Escherichia fergusonii Becca 0.07 EFB2_02921 Staphyloferrin B transporter 0.20 EFB2_00375 Glutathione hydrolase proenzyme low > 86
Escherichia coli Nissle 1917 0.07 ECOLIN_RS06115 multidrug efflux MFS transporter MdtG 0.20 ECOLIN_RS19715 gamma-glutamyltransferase
Escherichia coli BL21 0.07 ECD_01049 putative drug efflux system protein 0.20 ECD_03296 gamma-glutamyltranspeptidase low > 61
Escherichia coli ECOR27 0.07 NOLOHH_21305 mdtG multidrug efflux MFS transporter MdtG 0.20 NOLOHH_08590 ggt gamma-glutamyltransferase low > 75
Escherichia coli BW25113 0.07 b1053 mdtG predicted drug efflux system (NCBI) 0.20 b3447 ggt gamma-glutamyltranspeptidase periplasmic precursor (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.07 OHPLBJKB_02612 Multidrug resistance protein MdtG 0.20 OHPLBJKB_00256 Glutathione hydrolase proenzyme low > 73
Dickeya dianthicola ME23 0.07 DZA65_RS05960 MFS transporter 0.18 DZA65_RS14700 gamma-glutamyltransferase low > 75

Not shown: 10 genomes with orthologs for A4249_RS11115 only; 36 genomes with orthologs for A4249_RS14305 only