Conservation of cofitness between b3553 and b3642 in Escherichia coli BW25113

54 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3553 yiaE putative dehydrogenase (VIMSS) 1.0 b3642 pyrE orotate phosphoribosyltransferase (NCBI) 0.28 20
Escherichia coli ECRC101 1.00 MCAODC_06535 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.99 MCAODC_06110 pyrE Orotate phosphoribosyltransferase — —
Escherichia fergusonii Becca 1.00 EFB2_00254 Glyoxylate/hydroxypyruvate reductase B 1.00 EFB2_00171 Orotate phosphoribosyltransferase low > 86
Escherichia coli ECRC62 1.00 BNILDI_03580 ghrB glyoxylate/hydroxypyruvate reductase GhrB 1.00 BNILDI_04035 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECOR27 1.00 NOLOHH_07965 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.99 NOLOHH_07480 pyrE Orotate phosphoribosyltransferase low > 57
Escherichia coli ECRC99 1.00 KEDOAH_12130 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.99 KEDOAH_12550 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC102 1.00 NIAGMN_13780 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.99 NIAGMN_13360 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli BL21 1.00 ECD_03403 glyoxylate/hydroxypyruvate reductase B 1.00 ECD_03499 orotate phosphoribosyltransferase low > 60
Escherichia coli ECRC101 1.00 OKFHMN_16020 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.99 OKFHMN_15600 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC98 1.00 JDDGAC_19650 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.99 JDDGAC_19225 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECOR38 0.99 HEPCGN_14910 ghrB glyoxylate/hydroxypyruvate reductase GhrB 1.00 HEPCGN_14420 pyrE Orotate phosphoribosyltransferase low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS20330 glyoxylate/hydroxypyruvate reductase GhrB 1.00 ECOLIN_RS20750 orotate phosphoribosyltransferase low > 52
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_00153 Glyoxylate/hydroxypyruvate reductase B 1.00 OHPLBJKB_00060 Orotate phosphoribosyltransferase low > 73
Klebsiella michiganensis M5al 0.87 BWI76_RS26960 bifunctional glyoxylate/hydroxypyruvate reductase B 0.96 BWI76_RS27385 orotate phosphoribosyltransferase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF458 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 0.97 GFF367 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 78
Enterobacter sp. TBS_079 0.84 MPMX20_00177 Glyoxylate/hydroxypyruvate reductase B 0.94 MPMX20_00093 Orotate phosphoribosyltransferase low > 85
Enterobacter asburiae PDN3 0.81 EX28DRAFT_3817 Lactate dehydrogenase and related dehydrogenases 0.96 EX28DRAFT_3892 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Serratia liquefaciens MT49 0.74 IAI46_00085 glyoxylate/hydroxypyruvate reductase GhrB 0.91 IAI46_24845 orotate phosphoribosyltransferase low > 86
Rahnella sp. WP5 0.69 EX31_RS05925 glyoxylate/hydroxypyruvate reductase GhrB 0.90 EX31_RS14500 orotate phosphoribosyltransferase low > 89
Pantoea sp. MT58 0.69 IAI47_00110 glyoxylate/hydroxypyruvate reductase GhrB 0.87 IAI47_00600 orotate phosphoribosyltransferase low > 76
Pectobacterium carotovorum WPP14 0.69 HER17_RS21175 glyoxylate/hydroxypyruvate reductase GhrB 0.90 HER17_RS20850 orotate phosphoribosyltransferase low > 75
Dickeya dianthicola 67-19 0.68 HGI48_RS00175 glyoxylate/hydroxypyruvate reductase GhrB 0.88 HGI48_RS00680 orotate phosphoribosyltransferase low > 71
Dickeya dianthicola ME23 0.67 DZA65_RS00195 glyoxylate/hydroxypyruvate reductase GhrB 0.88 DZA65_RS00735 orotate phosphoribosyltransferase low > 75
Dickeya dadantii 3937 0.65 DDA3937_RS21080 glyoxylate/hydroxypyruvate reductase GhrB 0.90 DDA3937_RS20535 orotate phosphoribosyltransferase low > 74
Pseudomonas sp. RS175 0.56 PFR28_01596 Glyoxylate/hydroxypyruvate reductase B 0.71 PFR28_04417 Orotate phosphoribosyltransferase — —
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS09030 NAD(P)-dependent oxidoreductase 0.52 ABZR87_RS05590 orotate phosphoribosyltransferase low > 80
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_627 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.68 Pf6N2E2_4370 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_26885 phosphogluconate 2-dehydrogenase KguD (EC 1.1.1.43) (from data) 0.67 AO353_09245 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_24675 bifunctional glyoxylate/hydroxypyruvate reductase B 0.67 AO356_12520 orotate phosphoribosyltransferase low > 104
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_2948 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.67 PfGW456L13_788 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens SBW25 0.53 PFLU_RS13240 D-glycerate dehydrogenase 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS13240 D-glycerate dehydrogenase 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_4763 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.67 Pf1N1B4_2120 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas simiae WCS417 0.53 PS417_12555 phosphogluconate 2-dehydrogenase KguD (EC 1.1.1.43) (from data) 0.68 PS417_27795 orotate phosphoribosyltransferase low > 88
Herbaspirillum seropedicae SmR1 0.53 HSERO_RS07550 bifunctional glyoxylate/hydroxypyruvate reductase B 0.55 HSERO_RS23380 orotate phosphoribosyltransferase — —
Pseudomonas putida KT2440 0.48 PP_3376 putative phosphonate dehydrogenase 0.67 PP_5291 Orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.45 Psyr_1043 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.45 Psyr_1043 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Castellaniella sp019104865 MT123 0.45 ABCV34_RS08615 D-glycerate dehydrogenase 0.58 ABCV34_RS10890 orotate phosphoribosyltransferase — —
Variovorax sp. SCN45 0.43 GFF2715 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.49 GFF5065 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 127
Acinetobacter radioresistens SK82 0.42 MPMX26_01125 Glyoxylate/hydroxypyruvate reductase B 0.56 MPMX26_02937 Orotate phosphoribosyltransferase low > 36
Variovorax sp. OAS795 0.41 ABID97_RS20025 D-glycerate dehydrogenase 0.48 ABID97_RS03910 orotate phosphoribosyltransferase low > 91
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS09465 bifunctional glyoxylate/hydroxypyruvate reductase B 0.55 RR42_RS01225 orotate phosphoribosyltransferase — —
Ralstonia solanacearum PSI07 0.39 RPSI07_RS02805 D-glycerate dehydrogenase 0.52 RPSI07_RS23295 orotate phosphoribosyltransferase — —
Ralstonia solanacearum GMI1000 0.39 RS_RS21645 D-glycerate dehydrogenase 0.52 RS_RS00685 orotate phosphoribosyltransferase — —
Acidovorax sp. GW101-3H11 0.37 Ac3H11_2599 Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 0.51 Ac3H11_3341 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 79
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.1956.1 Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 0.47 Xcc-8004.4884.1 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 74
Lysobacter sp. OAE881 0.36 ABIE51_RS08225 D-glycerate dehydrogenase 0.46 ABIE51_RS00065 orotate phosphoribosyltransferase low > 62
Rhodanobacter sp. FW510-T8 0.34 OKGIIK_04810 D-glycerate dehydrogenase 0.59 OKGIIK_15685 pyrE orotate phosphoribosyltransferase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF3835 Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 0.49 GFF1882 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 90
Dyella japonica UNC79MFTsu3.2 0.31 ABZR86_RS08035 D-glycerate dehydrogenase 0.61 ABZR86_RS15640 orotate phosphoribosyltransferase low > 74
Ralstonia solanacearum UW163 0.30 UW163_RS11805 D-glycerate dehydrogenase 0.53 UW163_RS03505 orotate phosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.30 RALBFv3_RS14340 D-glycerate dehydrogenase 0.53 RALBFv3_RS10075 orotate phosphoribosyltransferase — —
Pseudomonas stutzeri RCH2 0.26 Psest_0431 Lactate dehydrogenase and related dehydrogenases 0.71 Psest_3810 orotate phosphoribosyltransferase low > 67
Shewanella oneidensis MR-1 0.21 SO3631 hprA glycerate dehydrogenase (NCBI ptt file) 0.82 SO4255 pyrE orotate phosphoribosyltransferase (NCBI ptt file) low > 76

Not shown: 25 genomes with orthologs for b3553 only; 16 genomes with orthologs for b3642 only