Conservation of cofitness between b2954 and b0948 in Escherichia coli BW25113

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2954 yggV putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) 1.0 b0948 ycbY predicted methyltransferase (NCBI) 0.35 19
Escherichia fergusonii Becca 0.99 EFB2_00948 dITP/XTP pyrophosphatase 0.99 EFB2_03123 Ribosomal RNA large subunit methyltransferase K/L low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS16430 XTP/dITP diphosphatase 0.99 ECOLIN_RS04980 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
Escherichia coli ECRC101 0.98 OKFHMN_19240 rdgB XTP/dITP diphosphatase 1.00 OKFHMN_05280 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
Escherichia coli ECRC102 0.98 NIAGMN_17005 rdgB XTP/dITP diphosphatase 1.00 NIAGMN_03000 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
Escherichia coli ECRC99 0.98 KEDOAH_08900 rdgB XTP/dITP diphosphatase 1.00 KEDOAH_22455 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
Escherichia coli ECOR27 0.98 NOLOHH_11110 rdgB XTP/dITP diphosphatase 1.00 NOLOHH_21835 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_00762 dITP/XTP pyrophosphatase 1.00 OHPLBJKB_02718 Ribosomal RNA large subunit methyltransferase K/L low > 73
Escherichia coli ECRC98 0.98 JDDGAC_22870 rdgB XTP/dITP diphosphatase 0.99 JDDGAC_08890 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
Escherichia coli ECRC62 0.98 BNILDI_09690 rdgB XTP/dITP diphosphatase 1.00 BNILDI_20000 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
Escherichia coli BL21 0.98 ECD_02784 dITP/XTP pyrophosphatase 1.00 ECD_00952 23S rRNA m(2)G2445 and m(7)G2069 methyltransferases, SAM-dependent
Escherichia coli ECRC101 0.98 MCAODC_09760 rdgB XTP/dITP diphosphatase 1.00 MCAODC_24670 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
Escherichia coli ECOR38 0.98 HEPCGN_18545 rdgB XTP/dITP diphosphatase 1.00 HEPCGN_23240 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF3057 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.92 GFF3239 23S rRNA (guanine-N-2-) -methyltransferase rlmL EC 2.1.1.-) low > 78
Enterobacter sp. TBS_079 0.91 MPMX20_03812 dITP/XTP pyrophosphatase 0.88 MPMX20_01599 Ribosomal RNA large subunit methyltransferase K/L low > 85
Klebsiella michiganensis M5al 0.90 BWI76_RS24115 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.88 BWI76_RS09925 23S rRNA (guanine(2445)-N(2))/(guanine(2069)-N(7))- methyltransferase low > 92
Enterobacter asburiae PDN3 0.90 EX28DRAFT_2992 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.88 EX28DRAFT_1995 Predicted N6-adenine-specific DNA methylase low > 76
Dickeya dianthicola 67-19 0.84 HGI48_RS17365 XTP/dITP diphosphatase 0.75 HGI48_RS12910 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 71
Dickeya dianthicola ME23 0.83 DZA65_RS18455 XTP/dITP diphosphatase 0.75 DZA65_RS13375 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 75
Dickeya dadantii 3937 0.83 DDA3937_RS17320 XTP/dITP diphosphatase 0.75 DDA3937_RS12840 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 74
Pantoea sp. MT58 0.82 IAI47_03585 XTP/dITP diphosphatase 0.76 IAI47_12690 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 76
Rahnella sp. WP5 0.82 EX31_RS02705 XTP/dITP diphosphatase 0.76 EX31_RS18080 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 89
Serratia liquefaciens MT49 0.79 IAI46_21430 XTP/dITP diphosphatase 0.77 IAI46_08820 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 86
Pectobacterium carotovorum WPP14 0.78 HER17_RS03790 XTP/dITP diphosphatase 0.77 HER17_RS11990 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 75
Erwinia tracheiphila SCR3 0.77 LU632_RS05450 XTP/dITP diphosphatase 0.76 LU632_RS09965 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 74
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_02430 non-canonical purine NTP pyrophosphatase 0.59 CSW01_07480 ribosomal RNA large subunit methyltransferase K/L low > 62
Marinobacter adhaerens HP15 0.66 HP15_281 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.40 HP15_1379 RNA methylase low > 73
Alteromonas macleodii MIT1002 0.63 MIT1002_00940 dITP/XTP pyrophosphatase 0.45 MIT1002_02036 Ribosomal RNA large subunit methyltransferase K/L low > 70
Kangiella aquimarina DSM 16071 0.59 B158DRAFT_0200 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.39 B158DRAFT_2229 23S rRNA m(2)G-2445 methyltransferase (EC 2.1.1.52) low > 40
Shewanella loihica PV-4 0.58 Shew_1132 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) 0.48 Shew_1812 23S rRNA m(2)G2445 methyltransferase (RefSeq)
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.1223.1 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.39 Xcc-8004.3335.1 23S rRNA (guanine-N-2-) -methyltransferase rlmL EC 2.1.1.-) low > 74
Shewanella amazonensis SB2B 0.56 Sama_2482 Ham1-like protein (RefSeq) 0.50 Sama_1600 rlmL 23S rRNA m(2)G2445 methyltransferase (RefSeq) low > 62
Shewanella sp. ANA-3 0.56 Shewana3_1189 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) 0.48 Shewana3_1601 rlmL 23S rRNA m(2)G2445 methyltransferase (RefSeq) low > 73
Lysobacter sp. OAE881 0.55 ABIE51_RS17295 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.37 ABIE51_RS14475 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 62
Shewanella oneidensis MR-1 0.55 SO3358 HAM1 protein (NCBI ptt file) 0.49 SO1851 conserved hypothetical protein (NCBI ptt file) low > 76
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS11905 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.41 ABZR86_RS21235 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 74
Pseudomonas syringae pv. syringae B728a ΔmexB 0.50 Psyr_0472 Ham1-like protein 0.42 Psyr_2108 23S rRNA m(2)G-2445 methyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.50 Psyr_0472 Ham1-like protein 0.42 Psyr_2108 23S rRNA m(2)G-2445 methyltransferase low > 86
Rhodanobacter sp. FW510-T8 0.50 OKGIIK_12155 rdgB RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.40 OKGIIK_03440 rlmKL bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 52
Acinetobacter radioresistens SK82 0.50 MPMX26_00400 dITP/XTP pyrophosphatase 0.37 MPMX26_01097 Ribosomal RNA large subunit methyltransferase K/L low > 36
Pseudomonas sp. S08-1 0.49 OH686_11015 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.43 OH686_03110 23S rRNA (guanine(2445)-N(2))-methyltransferase / 23S rRNA (guanine(2069)-N(7))-methyltransferase low > 80
Pseudomonas simiae WCS417 0.49 PS417_26755 nucleoside-triphosphate diphosphatase 0.41 PS417_20930 50S rRNA methyltransferase low > 88
Pseudomonas putida KT2440 0.49 PP_5100 dITP/XTP pyrophosphatase 0.43 PP_2096 fused 23S rRNA m2G2445 methyltransferase and 23S rRNA m7G2069 methyltransferase 0.27 17
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11465 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.41 LRK55_RS14315 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 63
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS11740 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.41 LRK54_RS14600 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 59
Pseudomonas fluorescens SBW25 0.49 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.41 PFLU_RS22545 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL low > 109
Pseudomonas fluorescens FW300-N2E3 0.49 AO353_08195 non-canonical purine NTP pyrophosphatase 0.40 AO353_00775 50S rRNA methyltransferase low > 101
Pseudomonas sp. RS175 0.49 PFR28_04248 dITP/XTP pyrophosphatase 0.40 PFR28_01055 Ribosomal RNA large subunit methyltransferase K/L low > 88
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.41 PFLU_RS22545 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL 0.14 87
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_13395 non-canonical purine NTP pyrophosphatase 0.40 AO356_02605 50S rRNA methyltransferase low > 104
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_4594 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.40 Pf6N2E2_2346 23S rRNA (guanine-N-2-) -methyltransferase rlmL EC 2.1.1.-) low > 103
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_1004 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.41 PfGW456L13_4094 23S rRNA (guanine-N-2-) -methyltransferase rlmL EC 2.1.1.-) low > 87
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_2335 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.40 Pf1N1B4_3844 23S rRNA (guanine-N-2-) -methyltransferase rlmL EC 2.1.1.-) low > 87
Pseudomonas stutzeri RCH2 0.48 Psest_0277 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family 0.44 Psest_1949 Predicted N6-adenine-specific DNA methylase low > 67

Not shown: 49 genomes with orthologs for b2954 only; 0 genomes with orthologs for b0948 only