| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Methanococcus maripaludis JJ | MMJJ_RS05145 | | 5,10-methylenetetrahydromethanopterin reductase | no data | 100 | 100 |
| o | Methanococcus maripaludis S2 | MMP_RS00340 | | 5 10-methylenetetrahydromethanopterin reductase | no data | 100 | 100 |
| | Mycobacterium tuberculosis H37Rv | Rv2951c | | Possible oxidoreductase | insig. | 28 | 86 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS21140 | | methylenetetrahydromethanopterin reductase | no data | 27 | 92 |
| o | Agrobacterium fabrum C58 | Atu5227 | | flavin-dependent oxidoreductase | no data | 25 | 87 |
| | Mycobacterium tuberculosis H37Rv | Rv0407 | | F420-dependent glucose-6-phosphate dehydrogenase Fgd1 | strong | 25 | 96 |
| | Mycobacterium tuberculosis H37Rv | Rv3520c | | Possible coenzyme F420-dependent oxidoreductase | insig. | 25 | 93 |
| | Sphingobium sp. HT1-2 | GFF4990 | | FIG01129245: hypothetical protein | insig. | 30 | 53 |
| | Sphingobium sp. HT1-2 | GFF928 | | Hydride transferase 1 | cofit | 29 | 56 |
| o | Rhizobium sp. OAE497 | ABIE40_RS21545 | | LLM class flavin-dependent oxidoreductase | insig. | 24 | 93 |
| | Mycobacterium tuberculosis H37Rv | Rv0132c | | Putative F420-dependent glucose-6-phosphate dehydrogenase Fgd2 | insig. | 27 | 50 |
| o | Azospirillum sp. SherDot2 | MPMX19_06822 | | Flavin-dependent trigonelline monooxygenase, oxygenase component | insig. | 24 | 93 |
| | Mycobacterium tuberculosis H37Rv | Rv1360 | | Probable oxidoreductase | insig. | 24 | 79 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS06460 | | LLM class flavin-dependent oxidoreductase | insig. | 24 | 90 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02779 | | FMNH(2)-dependent dimethylsulfone monooxygenase | cofit | 26 | 87 |
| | Pseudomonas simiae WCS417 | PS417_12635 | | alkanesulfonate monooxygenase | insig. | 27 | 87 |
| | Mycobacterium tuberculosis H37Rv | Rv1855c | | Possible oxidoreductase | insig. | 26 | 67 |
| | Marinobacter adhaerens HP15 | HP15_1692 | | luciferase family protein | cofit | 28 | 49 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS13330 | | dimethyl sulfone monooxygenase SfnG | insig. | 26 | 87 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS13330 | | dimethyl sulfone monooxygenase SfnG | insig. | 26 | 87 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01570 | | luciferase-type oxidoreductase, BA3436 family | insig. | 29 | 48 |
| | Sphingobium sp. HT1-2 | GFF4925 | | COG2141: Coenzyme F420-dependent N5,N10- methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases | cofit | 26 | 50 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4316 | | Alkanal monooxygenase alpha chain (EC 1.14.14.3) | insig. | 29 | 49 |
| | Pseudomonas orientalis W4I3 | QF045_RS17245 | | dimethyl sulfone monooxygenase SfnG | insig. | 26 | 87 |
| | Pseudomonas sp. RS175 | PFR28_02294 | | FMNH(2)-dependent dimethylsulfone monooxygenase | insig. | 25 | 87 |
| | Acinetobacter baumannii LAC-4 | RR41_RS00980 | | dimethyl sulfone monooxygenase SfnG | insig. | 24 | 88 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS06485 | | LLM class oxidoreductase | insig. | 28 | 46 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_05500 | | LLM class flavin-dependent oxidoreductase | sig. | 28 | 46 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS46310 | | LLM class oxidoreductase | insig. | 28 | 46 |
| | Dickeya dadantii 3937 | DDA3937_RS21120 | | putative FMN-dependent luciferase-like monooxygenase | insig. | 27 | 48 |
| o | Xanthobacter sp. DMC5 | GFF4569 | | Limonene 1,2-monooxygenase | insig. | 24 | 91 |
| | Pectobacterium carotovorum WPP14 | HER17_RS21200 | | putative FMN-dependent luciferase-like monooxygenase | insig. | 26 | 48 |
| | Mycobacterium tuberculosis H37Rv | Rv0044c | | Possible oxidoreductase | insig. | 26 | 63 |
| | Pseudomonas putida KT2440 | PP_2485 | | conserved protein of unknown function | insig. | 28 | 43 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS00255 | | TIGR03571 family LLM class oxidoreductase | insig. | 28 | 50 |
| | Azospirillum brasilense Sp245 | AZOBR_RS17815 | | bacterial luciferase family protein | insig. | 28 | 51 |
| | Pseudomonas stutzeri RCH2 | Psest_0903 | | luciferase-type oxidoreductase, BA3436 family | insig. | 27 | 43 |
| | Methylophilus sp. DMC18 | GFF1976 | | FMNH(2)-dependent dimethylsulfone monooxygenase | insig. | 25 | 87 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_28400 | | dimethyl sulfone monooxygenase SfnG | insig. | 25 | 78 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1435 | | Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; sulfonate monooxygenase | insig. | 25 | 78 |
| | Pseudomonas sp. BP01 | JOY50_RS03215 | | LLM class oxidoreductase | no data | 30 | 39 |
| | Agrobacterium fabrum C58 | Atu4293 | | monooxygenase | insig. | 27 | 44 |
| | Dickeya dianthicola 67-19 | HGI48_RS00140 | | putative FMN-dependent luciferase-like monooxygenase | insig. | 25 | 48 |
| | Acinetobacter baumannii LAC-4 | RR41_RS18765 | | FMNH2-dependent alkanesulfonate monooxygenase | insig. | 24 | 88 |
| | Sphingobium sp. HT1-2 | GFF2568 | | hypothetical protein | cofit | 24 | 50 |
| | Pseudomonas sp. BP01 | JOY50_RS06330 | | LLM class flavin-dependent oxidoreductase | insig. | 33 | 30 |
| | Mycobacterium tuberculosis H37Rv | Rv0953c | | Possible oxidoreductase | insig. | 24 | 60 |
| | Variovorax sp. SCN45 | GFF83 | | Alkanal monooxygenase alpha chain (EC 1.14.14.3) | insig. | 24 | 50 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS32010 | | 5,10-methylene tetrahydromethanopterin reductase | insig. | 38 | 24 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01174 | | Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase) | insig. | 28 | 42 |
| | Dickeya dianthicola ME23 | DZA65_RS00160 | | putative FMN-dependent luciferase-like monooxygenase | insig. | 25 | 48 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS32560 | | LLM class flavin-dependent oxidoreductase | insig. | 32 | 38 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS20390 | | LLM class flavin-dependent oxidoreductase | insig. | 24 | 89 |
| | Mycobacterium tuberculosis H37Rv | Rv0791c | | Conserved protein | insig. | 24 | 61 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4052 | | Bacterial luciferase family protein | insig. | 29 | 39 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS07635 | | alkanesulfonate monooxygenase | insig. | 25 | 57 |
| | Acinetobacter radioresistens SK82 | MPMX26_02904 | | FMNH(2)-dependent dimethylsulfone monooxygenase | insig. | 24 | 88 |
| | Variovorax sp. SCN45 | GFF4198 | | putative LuxA | insig. | 32 | 27 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS05240 | | LLM class flavin-dependent oxidoreductase | insig. | 26 | 40 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_12195 | | LLM class flavin-dependent oxidoreductase | insig. | 26 | 40 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS55365 | | LLM class flavin-dependent oxidoreductase | sig. | 26 | 40 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1559 | | luciferase | insig. | 37 | 25 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1559 | | luciferase | insig. | 37 | 25 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4577 | | Bacterial luciferase family protein | insig. | 26 | 39 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS14400 | | luciferase | insig. | 23 | 67 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1508 | | Luciferase-like monooxygenase (EC 1.14.-.-) | insig. | 28 | 32 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS23100 | | sugar ABC transporter substrate-binding protein | insig. | 33 | 24 |
| | Caulobacter crescentus NA1000 | CCNA_01227 | | alkanesulfonate monoxygenase | insig. | 27 | 58 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01227 | | alkanesulfonate monoxygenase | cofit | 27 | 58 |
| | Serratia liquefaciens MT49 | IAI46_01985 | | luciferase-like monooxygenase | insig. | 25 | 39 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_05850 | | luciferase-like monooxygenase | insig. | 29 | 32 |
| | Mycobacterium tuberculosis H37Rv | Rv2893 | | Possible oxidoreductase | insig. | 25 | 55 |
| | Caulobacter crescentus NA1000 | CCNA_02034 | | luciferase-like monooxygenase | sig. | 23 | 87 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02034 | | luciferase-like monooxygenase | insig. | 23 | 87 |
| | Pseudomonas sp. BP01 | JOY50_RS02555 | | LLM class oxidoreductase | insig. | 27 | 39 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS21140 | | dimethylsulfone monooxygenase SfnG | insig. | 25 | 91 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_06955 | | LLM class flavin-dependent oxidoreductase | insig. | 22 | 93 |
| | Klebsiella michiganensis M5al | BWI76_RS24980 | | LLM class flavin-dependent oxidoreductase | insig. | 29 | 32 |
| | Escherichia coli BL21 | ECD_03027 | | putative luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli ECOR38 | HEPCGN_17040 | yhbW | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Dechlorosoma suillum PS | Dsui_1879 | | luciferase family oxidoreductase, group 1 | cofit | 26 | 40 |
| | Pectobacterium carotovorum WPP14 | HER17_RS00140 | | FMNH2-dependent alkanesulfonate monooxygenase | cofit | 24 | 87 |
| | Dickeya dianthicola 67-19 | HGI48_RS03280 | | luciferase-like monooxygenase | insig. | 24 | 39 |
| | Escherichia fergusonii Becca | EFB2_00663 | | hypothetical protein | insig. | 28 | 32 |
| | Escherichia coli ECOR27 | NOLOHH_09965 | yhbW | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli ECRC62 | BNILDI_01565 | yhbW | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00540 | | hypothetical protein | insig. | 28 | 32 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS18150 | | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli BW25113 | b3160 | yhbW | predicted enzyme (NCBI) | sig. | 28 | 32 |
| | Escherichia coli ECRC100 | OKFHMN_18165 | yhbW | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli ECRC101 | MCAODC_08685 | yhbW | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli ECRC102 | NIAGMN_15925 | yhbW | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli ECRC98 | JDDGAC_21790 | yhbW | luciferase-like monooxygenase | insig. | 28 | 32 |
| | Escherichia coli ECRC99 | KEDOAH_09985 | yhbW | luciferase-like monooxygenase | no data | 28 | 32 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS04765 | | alkanesulfonate monooxygenase | insig. | 23 | 91 |
| | Pseudomonas stutzeri RCH2 | Psest_0077 | | luciferase family oxidoreductase, group 1 | insig. | 34 | 26 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_26590 | | 5,10-methylene tetrahydromethanopterin reductase | insig. | 29 | 32 |
| | Xanthobacter sp. DMC5 | GFF4289 | | hypothetical protein | insig. | 28 | 30 |
| | Pseudomonas sp. BP01 | JOY50_RS07675 | | LLM class flavin-dependent oxidoreductase | insig. | 23 | 89 |
| | Dickeya dianthicola 67-19 | HGI48_RS12940 | | FMNH2-dependent alkanesulfonate monooxygenase | insig. | 23 | 87 |