Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Shewanella amazonensis SB2B | Sama_2921 | | beta-lactamase class C-like protein (RefSeq) | insig. | 100 | 100 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_0225 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 30 | 92 |
o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS25350 | | serine hydrolase | insig. | 30 | 80 |
| Variovorax sp. SCN45 | GFF1777 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 27 | 70 |
o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1344 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 26 | 87 |
| Lysobacter sp. OAE881 | ABIE51_RS13660 | | serine hydrolase domain-containing protein | insig. | 26 | 65 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS19685 | | serine hydrolase domain-containing protein | insig. | 27 | 63 |
o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS10325 | | serine hydrolase | insig. | 24 | 83 |
| Rhodanobacter sp. FW510-T8 | OKGIIK_12395 | | Serine hydrolase | insig. | 25 | 76 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12150 | | serine hydrolase domain-containing protein | insig. | 25 | 66 |
| Shewanella loihica PV-4 | Shew_3053 | | Serine-type D-Ala-D-Ala carboxypeptidase (RefSeq) | insig. | 25 | 73 |
| Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS05545 | | serine hydrolase domain-containing protein | cofit | 26 | 65 |
| Rhodanobacter denitrificans MT42 | LRK55_RS11195 | | serine hydrolase domain-containing protein | cofit | 25 | 68 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS11465 | | serine hydrolase | insig. | 25 | 68 |
| Mycobacterium tuberculosis H37Rv | Rv1922 | | Probable conserved lipoprotein | insig. | 29 | 49 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_3675 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 30 | 62 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09335 | | serine hydrolase | insig. | 25 | 68 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_1656 | | D-alanyl-D-alanine dipeptidase | insig. | 25 | 80 |
| Magnetospirillum magneticum AMB-1 | AMB_RS18895 | | hypothetical protein | insig. | 27 | 65 |
| Alteromonas macleodii MIT1002 | MIT1002_01904 | | FmtA-like protein | insig. | 31 | 46 |
| Azospirillum sp. SherDot2 | MPMX19_04849 | | Penicillin-binding protein 4* | insig. | 25 | 71 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20210 | | serine hydrolase | sig. | 21 | 70 |
| Shewanella oneidensis MR-1 | SO0914 | | conserved hypothetical protein (NCBI ptt file) | insig. | 27 | 67 |
| Mycobacterium tuberculosis H37Rv | Rv0399c | | Possible conserved lipoprotein LpqK | insig. | 23 | 75 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS19605 | | serine hydrolase | strong | 25 | 59 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_2941 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 25 | 63 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS03465 | | serine hydrolase domain-containing protein | insig. | 23 | 66 |
| Lysobacter sp. OAE881 | ABIE51_RS17780 | | serine hydrolase domain-containing protein | insig. | 25 | 63 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS20415 | | serine hydrolase | insig. | 21 | 82 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_1175 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 24 | 90 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08675 | | hypothetical protein | sig. | 25 | 67 |
| Pantoea sp. MT58 | IAI47_21050 | | beta-lactamase family protein | insig. | 25 | 59 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2755 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 28 | 46 |
| Shewanella amazonensis SB2B | Sama_1351 | | beta-lactamase class C-like protein (RefSeq) | insig. | 25 | 67 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS19600 | | serine hydrolase domain-containing protein | insig. | 26 | 37 |
| Shewanella sp. ANA-3 | Shewana3_3369 | | beta-lactamase (RefSeq) | insig. | 26 | 67 |
| Escherichia fergusonii Becca | EFB2_01919 | | Protein flp | insig. | 25 | 59 |
| Escherichia coli Nissle 1917 | ECOLIN_RS11515 | | precolibactin peptidase ClbP | insig. | 25 | 59 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_11570 | | hypothetical protein | cofit | 25 | 68 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_06670 | | hypothetical protein | insig. | 23 | 67 |
| Variovorax sp. OAS795 | ABID97_RS23865 | | serine hydrolase domain-containing protein | insig. | 24 | 49 |
| Rhodopseudomonas palustris CGA009 | TX73_008260 | | serine hydrolase | insig. | 26 | 53 |
| Variovorax sp. OAS795 | ABID97_RS13055 | | serine hydrolase domain-containing protein | insig. | 25 | 41 |
| Variovorax sp. OAS795 | ABID97_RS27220 | | serine hydrolase domain-containing protein | insig. | 25 | 49 |
| Pseudomonas simiae WCS417 | PS417_14945 | | beta-lactamase | strong | 23 | 63 |
| Escherichia coli BL21 | ECD_00323 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase; penicillin-binding protein; weak beta-lactamase | insig. | 25 | 58 |
| Shewanella loihica PV-4 | Shew_2964 | | beta-lactamase (RefSeq) | insig. | 25 | 69 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03299 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 25 | 58 |
| Escherichia coli BW25113 | b0376 | ampH | beta-lactamase/D-alanine carboxypeptidase (NCBI) | sig. | 25 | 58 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS13840 | | serine hydrolase | insig. | 25 | 55 |
| Burkholderia phytofirmans PsJN | BPHYT_RS28610 | | beta-lactamase | insig. | 24 | 47 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_11035 | | hypothetical protein | insig. | 23 | 64 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_07820 | | hypothetical protein | insig. | 25 | 55 |
| Escherichia coli ECOR27 | NOLOHH_01590 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | cofit | 25 | 58 |
| Escherichia coli ECRC101 | OKFHMN_08665 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 58 |
| Escherichia coli ECRC101 | MCAODC_27890 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 58 |
| Escherichia coli ECRC102 | NIAGMN_06720 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 58 |
| Escherichia coli ECRC62 | BNILDI_23000 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | insig. | 25 | 58 |
| Escherichia coli ECRC98 | JDDGAC_12320 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | no data | 25 | 58 |
| Escherichia coli ECRC99 | KEDOAH_19305 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | no data | 25 | 58 |
| Azospirillum brasilense Sp245 | AZOBR_RS21025 | | beta-lactamase | insig. | 29 | 45 |
| Escherichia coli ECOR38 | HEPCGN_07305 | ampH | D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH | cofit | 25 | 58 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03890 | | Beta-lactamase | cofit | 24 | 51 |
| Escherichia fergusonii Becca | EFB2_04383 | | Beta-lactamase | insig. | 24 | 52 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS06895 | | serine hydrolase | insig. | 22 | 65 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18325 | | serine hydrolase domain-containing protein | insig. | 31 | 31 |
| Variovorax sp. SCN45 | GFF2397 | | Beta-lactamase class C-like and penicillin binding proteins (PBPs) superfamily | insig. | 27 | 39 |
| Escherichia coli ECOR38 | HEPCGN_10590 | blaEC | BlaEC family class C beta-lactamase | cofit | 24 | 51 |
| Escherichia coli ECOR27 | NOLOHH_04625 | blaEC | BlaEC family class C beta-lactamase | cofit | 24 | 51 |
| Escherichia coli ECRC101 | OKFHMN_12365 | blaEC | BlaEC family class C beta-lactamase | insig. | 24 | 51 |
| Escherichia coli ECRC101 | MCAODC_02875 | blaEC | BlaEC family class C beta-lactamase | insig. | 24 | 51 |
| Escherichia coli ECRC102 | NIAGMN_10210 | blaEC | BlaEC family class C beta-lactamase | insig. | 24 | 51 |
| Escherichia coli ECRC62 | BNILDI_06865 | blaEC | BlaEC family class C beta-lactamase | insig. | 24 | 51 |
| Escherichia coli ECRC98 | JDDGAC_16000 | blaEC | BlaEC family class C beta-lactamase | no data | 24 | 51 |
| Escherichia coli ECRC99 | KEDOAH_15800 | blaEC | BlaEC family class C beta-lactamase | no data | 24 | 51 |
| Escherichia coli Nissle 1917 | ECOLIN_RS24110 | | cephalosporin-hydrolyzing class C beta-lactamase EC-5 | insig. | 24 | 51 |
| Escherichia coli BW25113 | b4150 | ampC | beta-lactamase/D-alanine carboxypeptidase (NCBI) | strong | 24 | 51 |
| Rahnella sp. WP5 | EX31_RS20710 | | serine hydrolase | insig. | 27 | 39 |
| Azospirillum brasilense Sp245 | AZOBR_RS31140 | | beta-lactamase | insig. | 24 | 56 |
| Rhodopseudomonas palustris CGA009 | TX73_016980 | | serine hydrolase | insig. | 24 | 49 |
| Serratia liquefaciens MT49 | IAI46_11635 | | beta-lactamase family protein | insig. | 29 | 40 |
| Azospirillum sp. SherDot2 | MPMX19_06918 | | Esterase EstB | insig. | 24 | 75 |
| Pseudomonas sp. RS175 | PFR28_02010 | | Esterase EstB | insig. | 27 | 45 |
| Acidovorax sp. GW101-3H11 | Ac3H11_2935 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 25 | 48 |
| Escherichia coli BL21 | ECD_04022 | | penicillin-binding protein; beta-lactamase, intrinsically weak | insig. | 24 | 51 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_0607 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 23 | 67 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_1650 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 25 | 39 |
| Klebsiella michiganensis M5al | BWI76_RS06095 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 24 | 58 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS12620 | | serine hydrolase | insig. | 30 | 33 |
| Escherichia fergusonii Becca | EFB2_03681 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 24 | 47 |
| Escherichia coli Nissle 1917 | ECOLIN_RS02290 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 24 | 47 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04540 | | serine hydrolase | insig. | 22 | 74 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2342 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 22 | 54 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_4162 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 26 | 44 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4271 | | Penicillin-binding protein AmpH | insig. | 25 | 41 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1849.1 | | Beta-lactamase (EC 3.5.2.6) | insig. | 19 | 80 |
| Paraburkholderia graminis OAS925 | ABIE53_001872 | | CubicO group peptidase (beta-lactamase class C family) | insig. | 23 | 47 |
| Pantoea sp. MT58 | IAI47_05345 | | D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH | insig. | 24 | 44 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08185 | | hypothetical protein | insig. | 25 | 47 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_3004 | | Beta-lactamase class C and other penicillin binding proteins | insig. | 22 | 77 |