Conservation of cofitness between RR42_RS34650 and RR42_RS30660 in Cupriavidus basilensis FW507-4G11

48 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Cupriavidus basilensis FW507-4G11 1.0 RR42_RS34650 LacI family transcriptional regulator 1.0 RR42_RS30660 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.43 13
Variovorax sp. OAS795 0.44 ABID97_RS03270 LacI family DNA-binding transcriptional regulator 0.53 ABID97_RS19395 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 91
Variovorax sp. SCN45 0.44 GFF3450 Transcriptional regulator, LacI family 0.53 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) low > 127
Echinicola vietnamensis KMM 6221, DSM 17526 0.25 Echvi_3073 Transcriptional regulators 0.49 Echvi_2559 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase low > 79
Dyella japonica UNC79MFTsu3.2 0.24 ABZR86_RS01690 LacI family DNA-binding transcriptional regulator 0.49 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 74
Enterobacter sp. TBS_079 0.24 MPMX20_00737 Maltose regulon regulatory protein MalI 0.52 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase low > 85
Pectobacterium carotovorum WPP14 0.23 HER17_RS21525 ribose operon transcriptional repressor RbsR 0.51 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 75
Serratia liquefaciens MT49 0.23 IAI46_25050 ribose operon transcriptional repressor RbsR 0.53 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 86
Vibrio cholerae E7946 ATCC 55056 0.23 CSW01_14670 transcriptional repressor PurR 0.52 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase low > 62
Klebsiella michiganensis M5al 0.23 BWI76_RS00765 DNA-binding transcriptional regulator CytR 0.54 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.23 GFF2316 Transcriptional (co)regulator CytR 0.54 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.51 11
Escherichia coli ECRC101 0.23 MCAODC_04225 cytR DNA-binding transcriptional regulator CytR 0.53 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.23 OHPLBJKB_04117 HTH-type transcriptional repressor CytR 0.53 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase low > 73
Dickeya dadantii 3937 0.23 DDA3937_RS00055 ribose operon transcriptional repressor RbsR 0.52 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 74
Escherichia coli ECOR38 0.23 HEPCGN_12370 cytR DNA-binding transcriptional regulator CytR 0.53 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase low > 87
Escherichia coli ECRC98 0.23 JDDGAC_17350 cytR DNA-binding transcriptional regulator CytR 0.53 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase low > 86
Escherichia coli BW25113 0.23 b3934 cytR DNA-binding transcriptional dual regulator (NCBI) 0.53 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) low > 76
Escherichia coli BL21 0.23 ECD_03819 Anti-activator for CytR-CRP nucleoside utilization regulon 0.53 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase low > 61
Escherichia coli ECRC102 0.23 NIAGMN_11480 cytR DNA-binding transcriptional regulator CytR 0.53 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase — —
Escherichia coli ECRC100 0.23 OKFHMN_13725 cytR DNA-binding transcriptional regulator CytR 0.53 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase low > 80
Escherichia coli ECRC62 0.23 BNILDI_05660 cytR DNA-binding transcriptional regulator CytR 0.53 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase low > 75
Escherichia coli ECRC99 0.23 KEDOAH_14435 cytR DNA-binding transcriptional regulator CytR 0.53 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase — —
Escherichia coli ECOR27 0.23 NOLOHH_05870 cytR DNA-binding transcriptional regulator CytR 0.53 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase low > 75
Escherichia coli Nissle 1917 0.23 ECOLIN_RS22650 DNA-binding transcriptional regulator CytR 0.53 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 55
Ralstonia sp. UNC404CL21Col 0.23 ABZR87_RS09955 LacI family DNA-binding transcriptional regulator 0.61 ABZR87_RS20880 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 80
Escherichia fergusonii Becca 0.23 EFB2_04684 HTH-type transcriptional repressor CytR 0.53 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase low > 86
Ralstonia solanacearum GMI1000 0.23 RS_RS05020 LacI family transcriptional regulator 0.61 RS_RS20360 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.38 41
Pseudomonas fluorescens FW300-N2E3 0.23 AO353_20830 LacI family transcriptional regulator 0.55 AO353_16215 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase low > 101
Ralstonia solanacearum PSI07 0.23 RPSI07_RS19225 LacI family transcriptional regulator 0.61 RPSI07_RS02545 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.38 25
Dickeya dianthicola 67-19 0.22 HGI48_RS21310 ribose operon transcriptional repressor RbsR 0.51 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 71
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS14240 LacI family transcriptional regulator 0.61 RALBFv3_RS20320 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 76
Ralstonia solanacearum UW163 0.22 UW163_RS11705 LacI family transcriptional regulator 0.61 UW163_RS18855 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase — —
Rhodanobacter denitrificans FW104-10B01 0.22 LRK54_RS08670 LacI family transcriptional regulator 0.51 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 59
Rhodanobacter denitrificans MT42 0.22 LRK55_RS08435 LacI family DNA-binding transcriptional regulator 0.51 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 63
Pantoea sp. MT58 0.22 IAI47_00375 ribose operon transcriptional repressor RbsR 0.52 IAI47_18310 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 76
Pseudomonas fluorescens FW300-N1B4 0.22 Pf1N1B4_6032 Ribose operon repressor 0.55 Pf1N1B4_783 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) low > 87
Paraburkholderia sabiae LMG 24235 0.21 QEN71_RS38555 substrate-binding domain-containing protein 0.54 QEN71_RS19725 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 153
Pseudomonas sp. RS175 0.21 PFR28_02734 Ribose operon repressor 0.54 PFR28_03477 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase low > 88
Pseudomonas fluorescens FW300-N2E2 0.21 Pf6N2E2_164 Ribose operon repressor 0.55 Pf6N2E2_5472 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) low > 103
Mucilaginibacter yixingensis YX-36 DSM 26809 0.21 ABZR88_RS16160 LacI family DNA-binding transcriptional regulator 0.51 ABZR88_RS18615 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase — —
Pseudomonas fluorescens SBW25 0.21 PFLU_RS15195 LacI family transcriptional regulator 0.54 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 109
Pseudomonas fluorescens SBW25-INTG 0.21 PFLU_RS15195 LacI family transcriptional regulator 0.54 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 109
Pseudomonas fluorescens GW456-L13 0.20 PfGW456L13_3909 Ribose operon repressor 0.55 PfGW456L13_3767 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) low > 87
Acidovorax sp. GW101-3H11 0.20 Ac3H11_1840 Ribose operon repressor 0.58 Ac3H11_2345 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) low > 79
Pedobacter sp. GW460-11-11-14-LB5 0.18 CA265_RS21915 LacI family transcriptional regulator 0.50 CA265_RS21095 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 88
Bifidobacterium breve UCC2003 0.18 BBR_RS17775 LacI family DNA-binding transcriptional regulator 0.39 BBR_RS15405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase low > 34
Shewanella loihica PV-4 0.17 Shew_1111 LacI family transcription regulator (RefSeq) 0.50 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) low > 60
Mycobacterium tuberculosis H37Rv 0.16 Rv3575c Transcriptional regulatory protein (probably LacI-family) 0.46 Rv1133c Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme) — —
Pseudomonas stutzeri RCH2 0.15 Psest_3356 D-fructose-responsive transcription factor 0.56 Psest_1452 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase low > 67

Not shown: 21 genomes with orthologs for RR42_RS34650 only; 19 genomes with orthologs for RR42_RS30660 only