Conservation of cofitness between JDDGAC_28300 and JDDGAC_26850 in Escherichia coli ECRC98

59 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC98 1.0 JDDGAC_28300 mdtC multidrug efflux RND transporter permease subunit MdtC 1.0 JDDGAC_26850 nuoK NADH-quinone oxidoreductase subunit NuoK 0.62 6
Escherichia coli ECRC101 1.00 MCAODC_20750 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 MCAODC_13925 nuoK NADH-quinone oxidoreductase subunit NuoK low > 87
Escherichia coli ECRC99 1.00 KEDOAH_03960 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 KEDOAH_05310 nuoK NADH-quinone oxidoreductase subunit NuoK — —
Escherichia coli ECRC102 1.00 NIAGMN_22135 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NIAGMN_20655 nuoK NADH-quinone oxidoreductase subunit NuoK — —
Escherichia coli ECRC100 1.00 OKFHMN_24190 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 OKFHMN_22885 nuoK NADH-quinone oxidoreductase subunit NuoK low > 80
Escherichia coli ECOR27 1.00 NOLOHH_15535 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 NOLOHH_14505 nuoK NADH-quinone oxidoreductase subunit NuoK low > 75
Escherichia coli BL21 1.00 ECD_01981 multidrug efflux system, subunit C 1.00 ECD_02204 NADH:ubiquinone oxidoreductase, membrane subunit K low > 61
Escherichia coli ECRC62 1.00 BNILDI_14450 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 BNILDI_13425 nuoK NADH-quinone oxidoreductase subunit NuoK low > 75
Escherichia coli BW25113 0.99 b2076 mdtC multidrug efflux system, subunit C (NCBI) 1.00 b2279 nuoK NADH dehydrogenase subunit K (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01628 Multidrug resistance protein MdtC 1.00 OHPLBJKB_01427 NADH-quinone oxidoreductase subunit K low > 73
Escherichia coli ECOR38 0.99 HEPCGN_02880 mdtC multidrug efflux RND transporter permease subunit MdtC 1.00 HEPCGN_22090 nuoK NADH-quinone oxidoreductase subunit NuoK low > 87
Escherichia coli Nissle 1917 0.99 ECOLIN_RS12205 multidrug efflux RND transporter permease subunit MdtC 1.00 ECOLIN_RS13240 NADH-quinone oxidoreductase subunit NuoK — —
Escherichia fergusonii Becca 0.99 EFB2_01779 Multidrug resistance protein MdtC 1.00 EFB2_01580 NADH-quinone oxidoreductase subunit K low > 86
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0482 Cation/multidrug efflux pump 0.98 EX28DRAFT_0331 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) low > 76
Enterobacter sp. TBS_079 0.91 MPMX20_03062 Multidrug resistance protein MdtC 0.98 MPMX20_03209 NADH-quinone oxidoreductase subunit K low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3853 Multidrug transporter MdtC 0.99 GFF1882 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19260 multidrug transporter subunit MdtC 0.95 BWI76_RS20145 NADH-quinone oxidoreductase subunit K low > 92
Serratia liquefaciens MT49 0.82 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC 0.92 IAI46_17665 NADH-quinone oxidoreductase subunit NuoK low > 86
Pectobacterium carotovorum WPP14 0.79 HER17_RS06315 multidrug efflux RND transporter permease subunit MdtC 0.92 HER17_RS07170 NADH-quinone oxidoreductase subunit NuoK — —
Pantoea sp. MT58 0.79 IAI47_06865 multidrug efflux RND transporter permease subunit MdtC 0.85 IAI47_06405 NADH-quinone oxidoreductase subunit NuoK low > 76
Dickeya dianthicola 67-19 0.78 HGI48_RS15350 multidrug efflux RND transporter permease subunit MdtC 0.94 HGI48_RS14265 NADH-quinone oxidoreductase subunit NuoK — —
Dickeya dadantii 3937 0.78 DDA3937_RS15270 multidrug efflux RND transporter permease subunit MdtC 0.92 DDA3937_RS14290 NADH-quinone oxidoreductase subunit NuoK — —
Dickeya dianthicola ME23 0.78 DZA65_RS16170 multidrug efflux RND transporter permease subunit MdtC 0.93 DZA65_RS14940 NADH-quinone oxidoreductase subunit NuoK — —
Erwinia tracheiphila SCR3 0.73 LU632_RS08685 mdtC multidrug efflux RND transporter permease subunit MdtC 0.93 LU632_RS08010 nuoK NADH-quinone oxidoreductase subunit NuoK low > 74
Ralstonia solanacearum PSI07 0.63 RPSI07_RS05520 nodulation protein 0.37 RPSI07_RS14385 NADH-quinone oxidoreductase subunit K — —
Ralstonia solanacearum GMI1000 0.63 RS_RS22920 nodulation protein 0.37 RS_RS10295 NADH-quinone oxidoreductase subunit K — —
Ralstonia solanacearum UW163 0.63 UW163_RS21015 nodulation protein 0.37 UW163_RS10800 NADH-quinone oxidoreductase subunit K — —
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS18115 nodulation protein 0.37 RALBFv3_RS02925 NADH-quinone oxidoreductase subunit K — —
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS19020 multidrug efflux RND transporter permease subunit 0.37 ABZR87_RS14830 NADH-quinone oxidoreductase subunit NuoK — —
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS07655 nodulation protein 0.36 HSERO_RS08870 NADH-quinone oxidoreductase subunit K — —
Acidovorax sp. GW101-3H11 0.56 Ac3H11_3620 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.35 Ac3H11_1442 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) — —
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_22900 acriflavine resistance protein B 0.77 AO353_27785 NADH-quinone oxidoreductase subunit K — —
Pseudomonas sp. S08-1 0.55 OH686_00930 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type) 0.74 OH686_00110 NADH-ubiquinone oxidoreductase chain K — —
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_3265 Acriflavin resistance plasma membrane protein 0.74 PfGW456L13_2624 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) — —
Pseudomonas syringae pv. syringae B728a 0.53 Psyr_2484 Acriflavin resistance protein 0.75 Psyr_3206 NADH dehydrogenase subunit K — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.53 Psyr_2484 Acriflavin resistance protein 0.75 Psyr_3206 NADH dehydrogenase subunit K — —
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS13435 MMPL family transporter 0.75 PFLU_RS18660 NADH-quinone oxidoreductase subunit NuoK — —
Pseudomonas fluorescens SBW25 0.53 PFLU_RS13435 MMPL family transporter 0.75 PFLU_RS18660 NADH-quinone oxidoreductase subunit NuoK — —
Rahnella sp. WP5 0.53 EX31_RS13375 MMPL family transporter 0.92 EX31_RS19390 NADH-quinone oxidoreductase subunit NuoK low > 89
Pseudomonas simiae WCS417 0.52 PS417_12750 acriflavine resistance protein B 0.75 PS417_16620 NADH-quinone oxidoreductase subunit K — —
Pseudomonas putida KT2440 0.52 PP_3583 multidrug efflux transport system - membrane subunit 0.74 PP_4128 NADH-quinone oxidoreductase subunit K — —
Castellaniella sp019104865 MT123 0.52 ABCV34_RS14625 efflux RND transporter permease subunit 0.31 ABCV34_RS08700 NADH-quinone oxidoreductase subunit NuoK — —
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_1271 Acriflavin resistance plasma membrane protein 0.74 Pf6N2E2_268 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) — —
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_25880 acriflavine resistance protein B 0.74 AO356_22025 NADH-quinone oxidoreductase subunit K — —
Pseudomonas sp. RS175 0.51 PFR28_02193 Multidrug resistance protein MdtC 0.76 PFR28_02636 NADH-quinone oxidoreductase subunit K — —
Rhodopseudomonas palustris CGA009 0.49 TX73_018025 multidrug efflux RND transporter permease subunit 0.37 TX73_022045 NADH-quinone oxidoreductase subunit NuoK low > 86
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS29845 efflux RND transporter permease subunit 0.32 QEN71_RS24100 NADH-quinone oxidoreductase subunit NuoK — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.46 GFF488 RND multidrug efflux transporter; Acriflavin resistance protein 0.33 GFF3691 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) — —
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_06491 multidrug efflux pump 0.32 H281DRAFT_04577 NADH dehydrogenase subunit K — —
Azospirillum brasilense Sp245 0.44 AZOBR_RS14670 multidrug transporter 0.26 AZOBR_RS07215 NADH-quinone oxidoreductase — —
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS07780 nodulation protein 0.32 BPHYT_RS06675 NADH-quinone oxidoreductase subunit K — —
Bosea sp. OAE506 0.41 ABIE41_RS20140 efflux RND transporter permease subunit 0.29 ABIE41_RS17890 NADH-quinone oxidoreductase subunit NuoK — —
Agrobacterium fabrum C58 0.39 Atu3274 AcrB/AcrD/AcrF family protein 0.27 Atu1280 NADH ubiquinone oxidoreductase chain K — —
Variovorax sp. OAS795 0.39 ABID97_RS06490 efflux RND transporter permease subunit 0.37 ABID97_RS20445 NADH-quinone oxidoreductase subunit NuoK — —
Rhizobium sp. OAE497 0.38 ABIE40_RS05760 efflux RND transporter permease subunit 0.28 ABIE40_RS07235 NADH-quinone oxidoreductase subunit NuoK — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.24 CA264_13040 acriflavin resistance protein 0.59 CA264_04225 NADH-quinone oxidoreductase subunit K low > 74
Acinetobacter radioresistens SK82 0.23 MPMX26_02516 Multidrug resistance protein MdtC 0.70 MPMX26_02546 NADH-quinone oxidoreductase subunit K — —
Sinorhizobium meliloti 1021 0.23 SMc01457 transport transmembrane protein 0.40 SMa1544 NuoK2 NADH:quinone oxidoreductase subunit 11 (chain K) low > 103
Caulobacter crescentus NA1000 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.26 CCNA_02018 NADH-quinone oxidoreductase chain K — —
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_03301 cation/multidrug efflux pump AcrB 0.26 CCNA_02018 NADH-quinone oxidoreductase chain K — —

Not shown: 4 genomes with orthologs for JDDGAC_28300 only; 25 genomes with orthologs for JDDGAC_26850 only