Conservation of cofitness between HEPCGN_02885 and HEPCGN_09175 in Escherichia coli ECOR38

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 HEPCGN_09175 sltY murein transglycosylase 0.70 2
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 JDDGAC_14765 sltY murein transglycosylase low > 86
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NIAGMN_09020 sltY murein transglycosylase — —
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 OKFHMN_11170 sltY murein transglycosylase low > 80
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_16985 sltY murein transglycosylase — —
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NOLOHH_03500 sltY murein transglycosylase low > 75
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 1.00 ECOLIN_RS25210 murein transglycosylase low > 55
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b4392 slt soluble lytic murein transglycosylase (VIMSS) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 1.00 EFB2_04052 Soluble lytic murein transglycosylase low > 86
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_01685 sltY murein transglycosylase low > 87
Escherichia coli ECRC62 0.99 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 BNILDI_08095 sltY murein transglycosylase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_03669 Soluble lytic murein transglycosylase low > 73
Escherichia coli BL21 0.99 ECD_01980 multidrug efflux system, subunit B 0.99 ECD_04268 lytic murein transglycosylase, soluble low > 61
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.87 BWI76_RS04185 murein transglycosylase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3854 Multidrug transporter MdtB 0.91 GFF1060 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) 0.64 1
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.89 MPMX20_00699 Soluble lytic murein transglycosylase low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0483 Cation/multidrug efflux pump 0.89 EX28DRAFT_3602 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.65 IAI46_02985 murein transglycosylase low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.65 IAI47_16260 murein transglycosylase 0.29 34
Erwinia tracheiphila SCR3 0.79 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.66 LU632_RS02575 sltY murein transglycosylase low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.61 HER17_RS02750 murein transglycosylase low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.58 DDA3937_RS18455 murein transglycosylase low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.58 DZA65_RS19525 murein transglycosylase 0.55 11
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.58 HGI48_RS18385 murein transglycosylase low > 71
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.12 RPSI07_RS23510 lytic transglycosylase low > 81
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.12 ABZR87_RS04885 lytic transglycosylase domain-containing protein low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.12 RR42_RS01405 lytic transglycosylase low > 128
Pseudomonas sp. RS175 0.62 PFR28_02194 Multidrug resistance protein MdtB 0.22 PFR28_01106 Soluble lytic murein transglycosylase low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.22 AO356_02350 lytic transglycosylase low > 104
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.63 EX31_RS03985 murein transglycosylase low > 89
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.22 Pf6N2E2_2294 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) low > 103
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.21 PP_2130 putative Soluble lytic transglycosylase 0.17 73
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.23 OH686_21900 Soluble lytic murein transglycosylase 0.59 64
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.21 PfGW456L13_4045 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.22 AO353_00530 lytic transglycosylase low > 101
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.22 PFLU_RS07630 transglycosylase SLT domain-containing protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.22 PFLU_RS07630 transglycosylase SLT domain-containing protein low > 109
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.21 Pf1N1B4_3898 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) low > 87
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.22 PS417_07550 lytic transglycosylase low > 88
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.14 QEN71_RS28635 lytic transglycosylase domain-containing protein low > 153
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.13 H281DRAFT_05816 soluble lytic murein transglycosylase low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.21 Psyr_3295 SLT low > 86
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.21 Psyr_3295 SLT low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.22 Psest_1844 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.13 BPHYT_RS18610 lytic transglycosylase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.13 ABIE53_000044 soluble lytic murein transglycosylase low > 113
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.11 ABCV34_RS13560 transglycosylase SLT domain-containing protein low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.10 GFF1614 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) low > 90
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.11 ABID97_RS06595 transglycosylase SLT domain-containing protein low > 91
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS09845 efflux RND transporter permease subunit 0.16 LRK54_RS07245 transglycosylase SLT domain-containing protein low > 59
Rhodanobacter denitrificans MT42 0.50 LRK55_RS09505 efflux RND transporter permease subunit 0.16 LRK55_RS06980 transglycosylase SLT domain-containing protein low > 63
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS16320 efflux RND transporter permease subunit 0.16 ABZR86_RS12745 transglycosylase SLT domain-containing protein low > 74
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB 0.16 OKGIIK_16395 Lytic transglycosylase low > 52
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4792.1 Acriflavin resistance protein 0.15 Xcc-8004.961.1 Soluble lytic murein transglycosylase precursor (EC 3.2.1.-) low > 74

Not shown: 11 genomes with orthologs for HEPCGN_02885 only; 10 genomes with orthologs for HEPCGN_09175 only