Conservation of cofitness between ECD_00877 and ECD_03745 in Escherichia coli BL21

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00877 HCP oxidoreductase, NADH-dependent 1.0 ECD_03745 Cpx stress response Thr/Ser protein kinase; MazF antagonist protein low > 61
Escherichia coli ECRC62 1.00 BNILDI_20490 hcr NADH oxidoreductase 1.00 BNILDI_05225 srkA stress response kinase SrkA low > 75
Escherichia coli ECOR27 1.00 NOLOHH_22235 hcr NADH oxidoreductase 1.00 NOLOHH_06305 srkA stress response kinase SrkA low > 75
Escherichia coli BW25113 1.00 b0872 hcr HCP oxidoreductase, NADH-dependent (NCBI) 1.00 b3859 yihE predicted kinase (NCBI) low > 76
Escherichia fergusonii Becca 0.99 EFB2_03189 NADH oxidoreductase HCR 1.00 EFB2_04758 Stress response kinase A low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04640 NADH oxidoreductase 1.00 ECOLIN_RS22245 stress response kinase SrkA low > 55
Escherichia coli ECOR38 0.99 HEPCGN_02175 hcr NADH oxidoreductase 0.99 HEPCGN_12810 srkA stress response kinase SrkA low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_02796 NADH oxidoreductase HCR 1.00 OHPLBJKB_04194 Stress response kinase A low > 73
Escherichia coli ECRC102 0.99 NIAGMN_03880 hcr NADH oxidoreductase 1.00 NIAGMN_11930 srkA stress response kinase SrkA
Escherichia coli ECRC99 0.99 KEDOAH_22070 hcr NADH oxidoreductase 1.00 KEDOAH_13975 srkA stress response kinase SrkA
Escherichia coli ECRC101 0.99 MCAODC_25055 hcr NADH oxidoreductase 1.00 MCAODC_04675 srkA stress response kinase SrkA low > 87
Escherichia coli ECRC100 0.99 OKFHMN_05840 hcr NADH oxidoreductase 1.00 OKFHMN_14175 srkA stress response kinase SrkA low > 80
Escherichia coli ECRC98 0.99 JDDGAC_09475 hcr NADH oxidoreductase 1.00 JDDGAC_17800 srkA stress response kinase SrkA low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF4910 NADH oxidoreductase hcr (EC 1.-.-.-) 0.88 GFF2212 YihE protein, a ser/thr kinase implicated in LPS synthesis and Cpx signalling low > 78
Enterobacter sp. TBS_079 0.91 MPMX20_01534 NADH oxidoreductase HCR 0.82 MPMX20_04604 Stress response kinase A low > 85
Klebsiella michiganensis M5al 0.91 BWI76_RS09565 hybrid-cluster NAD(P)-dependent oxidoreductase 0.83 BWI76_RS00340 stress response kinase A 0.23 79
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2060 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.82 EX28DRAFT_4340 Putative homoserine kinase type II (protein kinase fold) low > 76
Pectobacterium carotovorum WPP14 0.62 HER17_RS12430 NADH oxidoreductase 0.71 HER17_RS21480 serine/threonine protein kinase low > 75
Serratia liquefaciens MT49 0.59 IAI46_08470 NADH oxidoreductase 0.70 IAI46_25000 serine/threonine protein kinase low > 86
Dickeya dadantii 3937 0.59 DDA3937_RS09535 NADH oxidoreductase 0.68 DDA3937_RS00095 serine/threonine protein kinase low > 74
Dickeya dianthicola 67-19 0.57 HGI48_RS09550 NADH oxidoreductase 0.67 HGI48_RS21270 serine/threonine protein kinase low > 71
Dickeya dianthicola ME23 0.57 DZA65_RS09860 NADH oxidoreductase 0.68 DZA65_RS22245 serine/threonine protein kinase low > 75
Rahnella sp. WP5 0.53 EX31_RS18595 NADH oxidoreductase 0.66 EX31_RS15915 serine/threonine protein kinase low > 89
Shewanella sp. ANA-3 0.27 Shewana3_3010 oxidoreductase FAD-binding subunit (RefSeq) 0.51 Shewana3_3839 serine/threonine protein kinase (RefSeq) low > 73
Shewanella loihica PV-4 0.27 Shew_1070 oxidoreductase FAD-binding subunit (RefSeq) 0.51 Shew_0264 serine/threonine protein kinase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.27 SO1364 iron-sulfur cluster-binding protein (NCBI ptt file) 0.52 SO0332 hypothetical kinase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.26 Sama_0896 iron-sulfur cluster-binding protein (RefSeq) 0.52 Sama_3322 serine/threonine protein kinase (RefSeq) low > 62
Ralstonia solanacearum GMI1000 0.23 RS_RS17500 hybrid-cluster NAD(P)-dependent oxidoreductase 0.42 RS_RS02700 serine/threonine protein kinase low > 80
Paraburkholderia sabiae LMG 24235 0.22 QEN71_RS08350 hybrid-cluster NAD(P)-dependent oxidoreductase 0.41 QEN71_RS00430 serine/threonine protein kinase low > 153
Pseudomonas simiae WCS417 0.22 PS417_26215 ferredoxin 0.44 PS417_26025 serine/threonine protein kinase low > 88
Pseudomonas fluorescens SBW25-INTG 0.22 PFLU_RS27860 glycine-betaine demethylase subunit GbcB 0.43 PFLU_RS27670 serine/threonine protein kinase low > 109
Pseudomonas fluorescens SBW25 0.22 PFLU_RS27860 glycine-betaine demethylase subunit GbcB 0.43 PFLU_RS27670 serine/threonine protein kinase low > 109
Paraburkholderia graminis OAS925 0.21 ABIE53_006130 ferredoxin-NADP reductase 0.40 ABIE53_000438 Ser/Thr protein kinase RdoA (MazF antagonist) low > 113
Pseudomonas fluorescens GW456-L13 0.21 PfGW456L13_1112 GbcB Glycine betaine demethylase subunit B 0.43 PfGW456L13_1143 YihE protein, required for LPS synthesis low > 87
Pseudomonas fluorescens FW300-N2C3 0.21 AO356_00630 ferredoxin 0.42 AO356_14115 serine/threonine protein kinase low > 104
Pseudomonas sp. RS175 0.21 PFR28_04139 3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component 0.42 PFR28_04107 Serine/threonine protein kinase RdoA low > 88
Paraburkholderia bryophila 376MFSha3.1 0.21 H281DRAFT_02476 Ferredoxin-NADP reductase 0.40 H281DRAFT_02190 Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist low > 103
Pseudomonas fluorescens FW300-N2E3 0.21 AO353_07675 ferredoxin 0.42 AO353_07545 serine/threonine protein kinase low > 101
Burkholderia phytofirmans PsJN 0.21 BPHYT_RS25220 ferredoxin oxidoreductase 0.41 BPHYT_RS01730 serine/threonine protein kinase low > 109
Pseudomonas syringae pv. syringae B728a 0.21 Psyr_4775 Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.40 Psyr_4697 Aminoglycoside phosphotransferase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.21 Psyr_4775 Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.40 Psyr_4697 Aminoglycoside phosphotransferase low > 86
Pseudomonas fluorescens FW300-N2E2 0.21 Pf6N2E2_4714 GbcB Glycine betaine demethylase subunit B 0.42 Pf6N2E2_4755 YihE protein, required for LPS synthesis low > 103
Pseudomonas fluorescens FW300-N1B4 0.21 Pf1N1B4_2448 GbcB Glycine betaine demethylase subunit B 0.43 Pf1N1B4_2481 YihE protein, required for LPS synthesis low > 87
Pseudomonas putida KT2440 0.21 PP_0316 putative glycine-betaine dioxygenase subunit 0.40 PP_0359 serine/threonine protein kinase low > 96
Pseudomonas sp. S08-1 0.19 OH686_04175 Flavodoxin (ferredoxin-NADPH reductases) family 1 0.41 OH686_10380 YihE protein, required for LPS synthesis low > 80
Cupriavidus basilensis FW507-4G11 0.16 RR42_RS23745 phenylacetic acid degradation protein 0.41 RR42_RS02875 serine/threonine protein kinase low > 128
Herbaspirillum seropedicae SmR1 0.15 HSERO_RS20630 phenylacetic acid degradation protein 0.44 HSERO_RS07220 serine/threonine protein kinase low > 78
Marinobacter adhaerens HP15 0.15 HP15_2701 phenylacetic acid degradation oxidoreductase PaaK 0.39 HP15_2490 kinase low > 73
Variovorax sp. SCN45 0.14 GFF6097 1,2-phenylacetyl-CoA epoxidase, subunit E (EC 1.14.13.149) 0.43 GFF3567 YihE protein, required for LPS synthesis low > 127
Ralstonia solanacearum PSI07 0.14 RPSI07_RS02150 phenylacetate-CoA oxygenase/reductase subunit PaaK 0.43 RPSI07_RS21320 serine/threonine protein kinase low > 81
Ralstonia solanacearum UW163 0.14 UW163_RS18535 phenylacetate-CoA oxygenase/reductase subunit PaaK 0.43 UW163_RS01710 serine/threonine protein kinase
Ralstonia solanacearum IBSBF1503 0.14 RALBFv3_RS20640 phenylacetate-CoA oxygenase/reductase subunit PaaK 0.43 RALBFv3_RS11880 serine/threonine protein kinase low > 76
Variovorax sp. OAS795 0.13 ABID97_RS22805 1,2-phenylacetyl-CoA epoxidase subunit PaaE 0.42 ABID97_RS00940 serine/threonine protein kinase low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.13 GFF1689 Phenylacetate-CoA oxygenase/reductase, PaaK subunit 0.40 GFF355 YihE protein, required for LPS synthesis low > 90

Not shown: 11 genomes with orthologs for ECD_00877 only; 13 genomes with orthologs for ECD_03745 only