| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_02430 | | non-canonical purine NTP pyrophosphatase | 1.0 | CSW01_14780 | | cation:proton antiporter | 0.52 | 16 |
| Marinobacter adhaerens HP15 | 0.56 | HP15_281 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | 0.46 | HP15_2589 | | NADH:ubiquinone/quinone oxidoreductase, chain 4L | low | > 73 |
| Pseudomonas syringae pv. syringae B728a | 0.54 | Psyr_0472 | | Ham1-like protein | 0.29 | Psyr_3253 | | multisubunit potassium/proton antiporter, PhaC subunit | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.54 | Psyr_0472 | | Ham1-like protein | 0.29 | Psyr_3253 | | multisubunit potassium/proton antiporter, PhaC subunit | low | > 86 |
| Rhodanobacter sp000427505 FW510-R12 | 0.53 | LRK53_RS16800 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.28 | LRK53_RS00915 | | Na+/H+ antiporter subunit C | low | > 59 |
| Pseudomonas fluorescens FW300-N2C3 | 0.53 | AO356_13395 | | non-canonical purine NTP pyrophosphatase | 0.29 | AO356_23275 | | cation:proton antiporter | low | > 104 |
| Rhodanobacter sp. FW510-T8 | 0.53 | OKGIIK_12155 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.26 | OKGIIK_14040 | mnhC | Na+/H+ antiporter subunit C | low | > 53 |
| Pseudomonas segetis P6 | 0.53 | MPMX49_00604 | | dITP/XTP pyrophosphatase | 0.34 | MPMX49_03489 | | Na(+)/H(+) antiporter subunit C1 | low | > 75 |
| Pseudomonas sp. RS175 | 0.53 | PFR28_04248 | | dITP/XTP pyrophosphatase | 0.29 | PFR28_02403 | | Na(+)/H(+) antiporter subunit C1 | low | > 88 |
| Pseudomonas fluorescens FW300-N2E2 | 0.52 | Pf6N2E2_4594 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | 0.29 | Pf6N2E2_537 | | Na(+) H(+) antiporter subunit C | low | > 103 |
| Pseudomonas sp. SVBP6 | 0.52 | COO64_RS12970 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.30 | COO64_RS19405 | | Na+/H+ antiporter subunit C | low | > 93 |
| Pseudomonas simiae WCS417 | 0.52 | PS417_26755 | | nucleoside-triphosphate diphosphatase | 0.29 | PS417_16835 | | monovalent cation/H+ antiporter subunit C | — | — |
| Pseudomonas lactucae CFBP13502 | 0.52 | GEMAOFIL_05488 | | dITP/XTP pyrophosphatase | 0.29 | GEMAOFIL_03685 | | Na(+)/H(+) antiporter subunit C1 | low | > 93 |
| Pseudomonas sp. DMC3 | 0.52 | GFF215 | | dITP/XTP pyrophosphatase | 0.26 | GFF1737 | | Na(+)/H(+) antiporter subunit C1 | low | > 89 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.52 | Xcc-8004.1223.1 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | 0.33 | Xcc-8004.588.1 | | Na(+) H(+) antiporter subunit C | — | — |
| Pseudomonas putida KT2440 | 0.52 | PP_5100 | | dITP/XTP pyrophosphatase | 0.31 | PP_2229 | | putative K(+)/H(+) antiporter subunit C | low | > 96 |
| Pseudomonas sp. BP01 | 0.52 | JOY50_RS20880 | rdgB | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.31 | JOY50_RS12575 | | Na+/H+ antiporter subunit C | low | > 84 |
| Pseudomonas aeruginosa PA14 | 0.52 | IKLFDK_23490 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.33 | IKLFDK_04835 | | Na+/H+ antiporter subunit C | low | > 100 |
| Pseudomonas fluorescens FW300-N2E3 | 0.51 | AO353_08195 | | non-canonical purine NTP pyrophosphatase | 0.29 | AO353_21465 | | cation:proton antiporter | low | > 101 |
| Pseudomonas fluorescens SBW25 | 0.51 | PFLU_RS28400 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.29 | PFLU_RS18845 | | Na+/H+ antiporter subunit C | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.51 | PFLU_RS28400 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.29 | PFLU_RS18845 | | Na+/H+ antiporter subunit C | — | — |
| Lysobacter sp. OAE881 | 0.51 | ABIE51_RS17295 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.33 | ABIE51_RS09890 | | Na+/H+ antiporter subunit C | low | > 62 |
| Pseudomonas fluorescens FW300-N1B4 | 0.51 | Pf1N1B4_2335 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | 0.28 | Pf1N1B4_5823 | | Na(+) H(+) antiporter subunit C | low | > 87 |
| Pseudomonas stutzeri RCH2 | 0.50 | Psest_0277 | | non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family | 0.40 | Psest_4370 | | Multisubunit Na+/H+ antiporter, MnhC subunit | low | > 67 |
| Pseudomonas sp. S08-1 | 0.50 | OH686_11015 | | non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family | 0.32 | OH686_04750 | | Na(+) H(+) antiporter subunit C | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.49 | LRK54_RS11740 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.26 | LRK54_RS07590 | | Na+/H+ antiporter subunit C | — | — |
| Rhodanobacter denitrificans MT42 | 0.49 | LRK55_RS11465 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.26 | LRK55_RS07330 | | Na+/H+ antiporter subunit C | low | > 63 |
| Acinetobacter radioresistens SK82 | 0.48 | MPMX26_00400 | | dITP/XTP pyrophosphatase | 0.29 | MPMX26_00260 | | Na(+)/H(+) antiporter subunit C1 | — | — |
| Acinetobacter baumannii LAC-4 | 0.46 | RR41_RS16630 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.32 | RR41_RS17270 | | Na+/H+ antiporter subunit C | — | — |
| Castellaniella sp019104865 MT123 | 0.44 | ABCV34_RS03520 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.33 | ABCV34_RS06475 | | Na+/H+ antiporter subunit C | low | > 48 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.38 | GFF3255 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | 0.30 | GFF2657 | | Na(+) H(+) antiporter subunit C | low | > 90 |
| Variovorax sp. SCN45 | 0.36 | GFF2382 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66) | 0.34 | GFF6172 | | Na(+) H(+) antiporter subunit C | low | > 127 |
| Variovorax sp. OAS795 | 0.35 | ABID97_RS23635 | | non-canonical purine NTP pyrophosphatase | 0.34 | ABID97_RS09450 | | Na+/H+ antiporter subunit C | low | > 91 |
| Acidovorax sp. GW101-3H11 | 0.35 | Ac3H11_3671 | | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) | 0.29 | Ac3H11_2583 | | Na(+) H(+) antiporter subunit C | low | > 79 |
| Agrobacterium fabrum C58 | 0.32 | Atu0326 | | putative deoxyribonucleotide triphosphate pyrophosphatase | 0.54 | Atu0911 | | Na+/H+ antiporter | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.31 | A4249_RS12440 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.30 | A4249_RS08485 | | Na+/H+ antiporter subunit C | — | — |
| Phaeobacter inhibens DSM 17395 | 0.31 | PGA1_c35040 | | nucleoside-triphosphatase RdgB | 0.32 | PGA1_c12260 | | monovalent cation/proton antiporter subunit C | — | — |
| Sinorhizobium meliloti 1021 | 0.30 | SMc01146 | | deoxyribonucleotide triphosphate pyrophosphatase | 0.44 | SMc00053 | | monovalent cation/H+ antiporter subunit C | low | > 103 |
| Rhizobium sp. OAE497 | 0.29 | ABIE40_RS01630 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.50 | ABIE40_RS05000 | | Na+/H+ antiporter subunit C | low | > 107 |
| Dinoroseobacter shibae DFL-12 | 0.29 | Dshi_3462 | | Ham1 family protein (RefSeq) | 0.38 | Dshi_0730 | | NADH-ubiquinone oxidoreductase chain 4L (RefSeq) | low | > 64 |
| Azospirillum sp. SherDot2 | 0.27 | MPMX19_02575 | | dITP/XTP pyrophosphatase | 0.30 | MPMX19_04696 | | Na(+)/H(+) antiporter subunit C1 | low | > 112 |
| Azospirillum brasilense Sp245 | 0.27 | AZOBR_RS02200 | | nucleoside-triphosphate diphosphatase | 0.28 | AZOBR_RS18305 | | cation:proton antiporter | — | — |
| Rhodopseudomonas palustris CGA009 | 0.26 | TX73_001705 | | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | 0.30 | TX73_014450 | | Na+/H+ antiporter subunit C | low | > 86 |
| Xanthobacter sp. DMC5 | 0.26 | GFF1892 | | dITP/XTP pyrophosphatase | 0.34 | GFF1223 | | Na(+)/H(+) antiporter subunit C | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.25 | CA264_19890 | | non-canonical purine NTP pyrophosphatase | 0.39 | CA264_06315 | | cation:proton antiporter | low | > 74 |
Not shown: 75 genomes with orthologs for CSW01_02430 only; 0 genomes with orthologs for CSW01_14780 only