Conservation of cofitness between CSW01_11730 and CSW01_13810 in Vibrio cholerae E7946 ATCC 55056

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11730 2-dehydropantoate 2-reductase 1.0 CSW01_13810 phosphoenolpyruvate carboxykinase (ATP) 0.82 14
Rahnella sp. WP5 0.38 EX31_RS22180 2-dehydropantoate 2-reductase 0.79 EX31_RS04780 phosphoenolpyruvate carboxykinase (ATP) low > 89
Enterobacter sp. TBS_079 0.36 MPMX20_01016 2-dehydropantoate 2-reductase 0.79 MPMX20_04290 Phosphoenolpyruvate carboxykinase (ATP) low > 85
Serratia liquefaciens MT49 0.35 IAI46_04950 2-dehydropantoate 2-reductase 0.81 IAI46_23770 phosphoenolpyruvate carboxykinase (ATP) low > 87
Escherichia coli ECRC102 0.35 NIAGMN_06450 panE 2-dehydropantoate 2-reductase 0.81 NIAGMN_14815 pckA phosphoenolpyruvate carboxykinase (ATP) low > 80
Escherichia coli ECRC99 0.35 KEDOAH_19570 panE 2-dehydropantoate 2-reductase 0.81 KEDOAH_11095 pckA phosphoenolpyruvate carboxykinase (ATP) — —
Escherichia coli ECRC98 0.35 JDDGAC_12050 panE 2-dehydropantoate 2-reductase 0.81 JDDGAC_20675 pckA phosphoenolpyruvate carboxykinase (ATP) low > 87
Escherichia coli BW25113 0.35 b0425 panE 2-dehydropantoate 2-reductase (NCBI) 0.81 b3403 pck phosphoenolpyruvate carboxykinase (NCBI) low > 76
Escherichia coli ECRC100 0.35 OKFHMN_08395 panE 2-dehydropantoate 2-reductase 0.81 OKFHMN_17045 pckA phosphoenolpyruvate carboxykinase (ATP) low > 79
Escherichia coli ECRC101 0.35 MCAODC_27620 panE 2-dehydropantoate 2-reductase 0.81 MCAODC_07575 pckA phosphoenolpyruvate carboxykinase (ATP) low > 87
Escherichia coli ECRC62 0.35 BNILDI_22760 panE 2-dehydropantoate 2-reductase 0.81 BNILDI_02685 pckA phosphoenolpyruvate carboxykinase (ATP) low > 75
Escherichia coli ECOR38 0.35 HEPCGN_07025 panE 2-dehydropantoate 2-reductase 0.81 HEPCGN_15865 pckA phosphoenolpyruvate carboxykinase (ATP) low > 88
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_03251 2-dehydropantoate 2-reductase 0.81 OHPLBJKB_00300 Phosphoenolpyruvate carboxykinase (ATP) low > 74
Enterobacter asburiae PDN3 0.35 EX28DRAFT_2546 2-dehydropantoate 2-reductase 0.79 EX28DRAFT_4140 phosphoenolpyruvate carboxykinase (ATP) low > 76
Escherichia coli ECOR27 0.35 NOLOHH_01345 panE 2-dehydropantoate 2-reductase 0.81 NOLOHH_08835 pckA phosphoenolpyruvate carboxykinase (ATP) low > 76
Escherichia coli BL21 0.35 ECD_00373 2-dehydropantoate reductase, NADPH-specific 0.81 ECD_03255 phosphoenolpyruvate carboxykinase [ATP] low > 61
Escherichia fergusonii Becca 0.35 EFB2_03632 2-dehydropantoate 2-reductase 0.81 EFB2_00425 Phosphoenolpyruvate carboxykinase (ATP) low > 86
Klebsiella pneumoniae MKP103 0.35 KDGMDA_14500 2-dehydropantoate 2-reductase 0.81 KDGMDA_06970 phosphoenolpyruvate carboxykinase (ATP) low > 95
Escherichia coli Nissle 1917 0.34 ECOLIN_RS02560 2-dehydropantoate 2-reductase 0.81 ECOLIN_RS19435 phosphoenolpyruvate carboxykinase (ATP) low > 55
Pectobacterium carotovorum WPP14 0.34 HER17_RS15910 2-dehydropantoate 2-reductase 0.80 HER17_RS01710 phosphoenolpyruvate carboxykinase (ATP) low > 75
Klebsiella michiganensis M5al 0.34 BWI76_RS06405 2-dehydropantoate 2-reductase 0.79 BWI76_RS26155 phosphoenolpyruvate carboxykinase (ATP) low > 92
Dickeya dianthicola ME23 0.34 DZA65_RS05940 2-dehydropantoate 2-reductase 0.81 DZA65_RS20830 phosphoenolpyruvate carboxykinase (ATP) low > 75
Dickeya dianthicola 67-19 0.33 HGI48_RS05615 2-dehydropantoate 2-reductase 0.81 HGI48_RS19740 phosphoenolpyruvate carboxykinase (ATP) low > 71
Pantoea agglomerans CFBP13505 P0401 0.32 PagCFBP13505_RS10480 2-dehydropantoate 2-reductase 0.77 PagCFBP13505_RS18350 phosphoenolpyruvate carboxykinase (ATP) low > 74
Pantoea sp. MT58 0.32 IAI47_14715 2-dehydropantoate 2-reductase 0.77 IAI47_01830 phosphoenolpyruvate carboxykinase (ATP) low > 76
Dickeya dadantii 3937 0.32 DDA3937_RS05555 2-dehydropantoate 2-reductase 0.81 DDA3937_RS19610 phosphoenolpyruvate carboxykinase (ATP) low > 74
Erwinia tracheiphila HP pepo 2.2 0.32 IJEDHG_16335 panE 2-dehydropantoate 2-reductase 0.78 IJEDHG_11970 pckA phosphoenolpyruvate carboxykinase (ATP) low > 61
Erwinia tracheiphila SCR3 0.32 LU632_RS18455 panE 2-dehydropantoate 2-reductase 0.78 LU632_RS22930 pckA phosphoenolpyruvate carboxykinase (ATP) low > 73
Erwinia amylovora T8 0.32 OLJFJH_18040 2-dehydropantoate 2-reductase 0.78 OLJFJH_04150 phosphoenolpyruvate carboxykinase (ATP) low > 58
Shewanella sp. ANA-3 0.32 Shewana3_0780 2-dehydropantoate 2-reductase (RefSeq) 0.36 Shewana3_0147 phosphoenolpyruvate carboxykinase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.31 SO3817 panE 2-dehydropantoate 2-reductase (NCBI ptt file) 0.36 SO0162 pckA phosphoenolpyruvate carboxykinase (ATP) (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.31 Shew_2895 2-dehydropantoate 2-reductase (RefSeq) 0.37 Shew_3623 phosphoenolpyruvate carboxykinase (RefSeq) low > 60
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.30 GFF4336 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.81 GFF615 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) low > 78
Alteromonas macleodii MIT1002 0.28 MIT1002_01217 2-dehydropantoate 2-reductase 0.36 MIT1002_03972 Phosphoenolpyruvate carboxykinase [ATP] low > 70
Pseudomonas sp. SVBP6 0.27 COO64_RS11970 putative 2-dehydropantoate 2-reductase 0.33 COO64_RS00660 phosphoenolpyruvate carboxykinase low > 93
Pseudomonas stutzeri RCH2 0.27 Psest_1140 2-dehydropantoate 2-reductase 0.33 Psest_3988 phosphoenolpyruvate carboxykinase (ATP) low > 67
Shewanella amazonensis SB2B 0.27 Sama_2559 2-dehydropantoate 2-reductase (RefSeq) 0.38 Sama_0165 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) (from data) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_4088 ketopantoate reductase 0.33 Psyr_0168 Phosphoenolpyruvate carboxykinase (ATP) low > 86
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_4088 ketopantoate reductase 0.33 Psyr_0168 Phosphoenolpyruvate carboxykinase (ATP) low > 86
Pseudomonas aeruginosa PUPa3 0.25 DQ20_RS56950 putative 2-dehydropantoate 2-reductase 0.34 DQ20_RS50285 phosphoenolpyruvate carboxykinase low > 101
Pseudomonas aeruginosa MRSN321 0.24 DY961_RS24500 putative 2-dehydropantoate 2-reductase 0.34 DY961_RS11825 phosphoenolpyruvate carboxykinase — —
Pseudomonas aeruginosa PA14 0.24 IKLFDK_02110 putative 2-dehydropantoate 2-reductase 0.34 IKLFDK_27515 phosphoenolpyruvate carboxykinase low > 98
Marinobacter adhaerens HP15 0.24 HP15_1312 2-dehydropantoate 2-reductase 0.36 HP15_3498 phosphoenolpyruvate carboxykinase (ATP) — —
Pseudomonas sp. RS175 0.24 PFR28_03426 2-dehydropantoate 2-reductase 0.34 PFR28_04874 Phosphoenolpyruvate carboxykinase (ATP) low > 88
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_17955 2-dehydropantoate 2-reductase 0.32 AO356_10140 phosphoenolpyruvate carboxykinase [ATP] low > 104
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_5521 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.32 Pf6N2E2_3899 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) low > 103
Pseudomonas segetis P6 0.23 MPMX49_03786 2-dehydropantoate 2-reductase 0.32 MPMX49_00777 Phosphoenolpyruvate carboxykinase (ATP) low > 75
Pseudomonas sp. BP01 0.23 JOY50_RS15040 putative 2-dehydropantoate 2-reductase 0.33 JOY50_RS18315 phosphoenolpyruvate carboxykinase low > 84
Pseudomonas fluorescens FW300-N2E3 0.23 AO353_03645 2-dehydropantoate 2-reductase 0.33 AO353_11775 phosphoenolpyruvate carboxykinase [ATP] low > 101
Pseudomonas sp. S08-1 0.23 OH686_08220 2-dehydropantoate 2-reductase 0.32 OH686_11060 phosphoenolpyruvate carboxykinase (ATP) low > 80
Pseudomonas orientalis W4I3 0.22 QF045_RS24680 putative 2-dehydropantoate 2-reductase 0.35 QF045_RS04340 phosphoenolpyruvate carboxykinase low > 93
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_1839 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.33 PfGW456L13_420 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) low > 87
Pseudomonas fluorescens FW300-N1B4 0.22 Pf1N1B4_651 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.34 Pf1N1B4_1779 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) — —
Pseudomonas simiae WCS417 0.22 PS417_22515 2-dehydropantoate 2-reductase 0.34 PS417_01210 hypothetical protein low > 88
Pseudomonas sp. DMC3 0.22 GFF5199 2-dehydropantoate 2-reductase 0.33 GFF4175 Phosphoenolpyruvate carboxykinase (ATP) low > 89
Pseudomonas fluorescens SBW25 0.21 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.34 PFLU_RS01320 phosphoenolpyruvate carboxykinase low > 109
Pseudomonas fluorescens SBW25-INTG 0.21 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.34 PFLU_RS01320 phosphoenolpyruvate carboxykinase low > 109
Rhodopseudomonas palustris CGA009 0.21 TX73_023700 2-dehydropantoate 2-reductase 0.42 TX73_001865 phosphoenolpyruvate carboxykinase — —
Pseudomonas lactucae CFBP13502 0.21 GEMAOFIL_04655 2-dehydropantoate 2-reductase 0.35 GEMAOFIL_00469 Phosphoenolpyruvate carboxykinase (ATP) low > 96
Bosea sp. OAE506 0.20 ABIE41_RS11280 2-dehydropantoate 2-reductase 0.40 ABIE41_RS02665 phosphoenolpyruvate carboxykinase low > 77
Pontibacter actiniarum KMM 6156, DSM 19842 0.11 CA264_06150 hypothetical protein 0.44 CA264_05270 phosphoenolpyruvate carboxykinase (ATP) — —

Not shown: 25 genomes with orthologs for CSW01_11730 only; 19 genomes with orthologs for CSW01_13810 only