Conservation of cofitness between CSW01_07735 and CSW01_12910 in Vibrio cholerae E7946 ATCC 55056

56 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_07735 multidrug resistance protein NorM 1.0 CSW01_12910 peptide-methionine (S)-S-oxide reductase 0.69 13
Pectobacterium carotovorum WPP14 0.55 HER17_RS09220 MATE family efflux transporter 0.54 HER17_RS03975 peptide-methionine (S)-S-oxide reductase MsrA low > 75
Enterobacter sp. TBS_079 0.55 MPMX20_01973 Multidrug resistance protein MdtK 0.52 MPMX20_00502 Peptide methionine sulfoxide reductase MsrA low > 85
Serratia liquefaciens MT49 0.54 IAI46_11210 MATE family efflux transporter 0.57 IAI46_01765 peptide-methionine (S)-S-oxide reductase MsrA low > 86
Klebsiella michiganensis M5al 0.54 BWI76_RS16535 MATE family efflux transporter 0.54 BWI76_RS02770 peptide-methionine (S)-S-oxide reductase low > 92
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_02061 Multidrug resistance protein MdtK 0.52 OHPLBJKB_03814 Peptide methionine sulfoxide reductase MsrA low > 74
Escherichia coli Nissle 1917 0.54 ECOLIN_RS09270 multidrug efflux MATE transporter MdtK 0.51 ECOLIN_RS24500 peptide-methionine (S)-S-oxide reductase MsrA — —
Escherichia fergusonii Becca 0.54 EFB2_02329 Multidrug resistance protein MdtK 0.52 EFB2_04310 Peptide methionine sulfoxide reductase MsrA low > 86
Escherichia coli BW25113 0.54 b1663 mdtK multidrug efflux protein NorM (NCBI) 0.52 b4219 msrA methionine sulfoxide reductase A (NCBI) low > 76
Escherichia coli BL21 0.54 ECD_01634 multidrug efflux system transporter 0.52 ECD_04090 methionine sulfoxide reductase A low > 61
Escherichia coli ECRC99 0.54 KEDOAH_00750 mdtK multidrug efflux MATE transporter MdtK 0.52 KEDOAH_16150 msrA Peptide methionine sulfoxide reductase MsrA — —
Escherichia coli ECRC100 0.54 OKFHMN_27360 mdtK multidrug efflux MATE transporter MdtK 0.52 OKFHMN_12005 msrA Peptide methionine sulfoxide reductase MsrA low > 79
Escherichia coli ECRC98 0.54 JDDGAC_01950 mdtK multidrug efflux MATE transporter MdtK 0.52 JDDGAC_15645 msrA Peptide methionine sulfoxide reductase MsrA low > 87
Escherichia coli ECRC102 0.54 NIAGMN_00705 mdtK multidrug efflux MATE transporter MdtK 0.52 NIAGMN_09855 msrA Peptide methionine sulfoxide reductase MsrA low > 80
Escherichia coli ECRC101 0.54 MCAODC_18050 mdtK multidrug efflux MATE transporter MdtK 0.52 MCAODC_02520 msrA Peptide methionine sulfoxide reductase MsrA low > 88
Escherichia coli ECOR38 0.54 HEPCGN_05745 mdtK multidrug efflux MATE transporter MdtK 0.52 HEPCGN_10205 msrA Peptide methionine sulfoxide reductase MsrA low > 88
Escherichia coli ECOR27 0.54 NOLOHH_17880 mdtK multidrug efflux MATE transporter MdtK 0.52 NOLOHH_04265 msrA Peptide methionine sulfoxide reductase MsrA low > 76
Rahnella sp. WP5 0.54 EX31_RS13855 MATE family efflux transporter 0.57 EX31_RS08700 peptide-methionine (S)-S-oxide reductase MsrA low > 89
Escherichia coli ECRC62 0.54 BNILDI_16670 mdtK multidrug efflux MATE transporter MdtK 0.52 BNILDI_07250 msrA Peptide methionine sulfoxide reductase MsrA low > 75
Klebsiella pneumoniae MKP103 0.54 KDGMDA_23495 MdtK family multidrug efflux MATE transporter 0.58 KDGMDA_11245 Peptide methionine sulfoxide reductase MsrA low > 95
Enterobacter asburiae PDN3 0.54 EX28DRAFT_1660 putative efflux protein, MATE family 0.51 EX28DRAFT_3405 methionine-S-sulfoxide reductase low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.53 GFF3613 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.53 GFF872 Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) low > 78
Dickeya dianthicola 67-19 0.53 HGI48_RS12700 MATE family efflux transporter 0.55 HGI48_RS17220 peptide-methionine (S)-S-oxide reductase MsrA low > 71
Dickeya dianthicola ME23 0.53 DZA65_RS13155 MATE family efflux transporter 0.55 DZA65_RS18300 peptide-methionine (S)-S-oxide reductase MsrA low > 75
Pseudomonas segetis P6 0.44 MPMX49_02327 Multidrug resistance protein NorM 0.59 MPMX49_04215 Peptide methionine sulfoxide reductase MsrA low > 75
Pseudomonas fluorescens FW300-N1B4 0.43 Pf1N1B4_3892 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.56 Pf1N1B4_1480 Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) low > 87
Pseudomonas sp. DMC3 0.42 GFF1263 Multidrug resistance protein NorM 0.55 GFF3150 Peptide methionine sulfoxide reductase MsrA low > 89
Pseudomonas lactucae CFBP13502 0.42 GEMAOFIL_01638 Multidrug resistance protein NorM 0.54 GEMAOFIL_00677 Peptide methionine sulfoxide reductase MsrA low > 93
Pseudomonas simiae WCS417 0.42 PS417_07530 multidrug transporter 0.55 PS417_02205 peptide methionine sulfoxide reductase low > 88
Pseudomonas fluorescens SBW25-INTG 0.42 PFLU_RS07610 MATE family efflux transporter 0.55 PFLU_RS02260 peptide-methionine (S)-S-oxide reductase MsrA low > 109
Pseudomonas fluorescens SBW25 0.42 PFLU_RS07610 MATE family efflux transporter 0.55 PFLU_RS02260 peptide-methionine (S)-S-oxide reductase MsrA low > 109
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_02370 MATE family efflux transporter 0.57 AO356_08980 peptide methionine sulfoxide reductase low > 104
Pseudomonas fluorescens FW300-N2E3 0.40 AO353_00550 MATE family efflux transporter 0.57 AO353_12845 peptide methionine sulfoxide reductase low > 101
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_4049 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.55 PfGW456L13_218 Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) low > 87
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2298 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps 0.56 Pf6N2E2_3678 Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) low > 103
Pseudomonas sp. RS175 0.40 PFR28_01102 Multidrug resistance protein NorM 0.56 PFR28_05057 Peptide methionine sulfoxide reductase MsrA low > 88
Pseudomonas sp. SVBP6 0.40 COO64_RS05190 MATE family efflux transporter 0.58 COO64_RS26695 msrA peptide-methionine (S)-S-oxide reductase MsrA low > 93
Pseudomonas aeruginosa PA14 0.39 IKLFDK_06480 proton-coupled multidrug efflux MATE transporter PmpM 0.58 IKLFDK_28445 Peptide methionine sulfoxide reductase MsrA low > 100
Dyella japonica UNC79MFTsu3.2 0.31 ABZR86_RS12525 MATE family efflux transporter 0.53 ABZR86_RS19340 peptide-methionine (S)-S-oxide reductase MsrA low > 74
Kangiella aquimarina DSM 16071 0.25 B158DRAFT_2495 putative efflux protein, MATE family 0.47 B158DRAFT_1498 methionine-S-sulfoxide reductase low > 40
Xanthomonas campestris pv. campestris strain 8004 0.24 Xcc-8004.4760.1 Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM 0.53 Xcc-8004.4229.1 Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11) low > 74
Synechocystis sp000284455 PCC 6803 0.20 SGL_RS14765 MATE family efflux transporter 0.59 SGL_RS02100 peptide-methionine (S)-S-oxide reductase MsrA low > 52
Agrobacterium fabrum C58 0.19 Atu2172 multidrug efflux protein 0.54 Atu0125 peptide methionine sulfoxide reductase low > 89
Pseudomonas sp. BP01 0.19 JOY50_RS09165 NorM family multidrug efflux MATE transporter 0.56 JOY50_RS17795 msrA peptide-methionine (S)-S-oxide reductase MsrA low > 84
Sinorhizobium meliloti 1021 0.19 SMc01211 hypothetical protein 0.55 SMc02885 methionine sulfoxide reductase A low > 103
Synechococcus elongatus PCC 7942 0.19 Synpcc7942_1699 MATE efflux family protein 0.53 Synpcc7942_1937 msrA peptide methionine sulfoxide reductase low > 38
Rhodopseudomonas palustris CGA009 0.19 TX73_004890 MATE family efflux transporter 0.56 TX73_025120 peptide-methionine (S)-S-oxide reductase MsrA low > 86
Bosea sp. OAE506 0.18 ABIE41_RS08515 MATE family efflux transporter 0.58 ABIE41_RS03175 peptide-methionine (S)-S-oxide reductase MsrA low > 77
Pseudomonas putida KT2440 0.18 PP_5262 Probable multidrug resistance protein NorM 0.58 PP_0336 Peptide methionine sulfoxide reductase MsrA low > 96
Pseudomonas syringae pv. syringae B728a 0.18 Psyr_0073 Multi antimicrobial extrusion protein MatE 0.59 Psyr_4771 Peptide methionine sulfoxide reductase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.18 Psyr_0073 Multi antimicrobial extrusion protein MatE 0.59 Psyr_4771 Peptide methionine sulfoxide reductase low > 86
Dinoroseobacter shibae DFL-12 0.17 Dshi_0755 MATE efflux family protein (RefSeq) 0.59 Dshi_1099 peptide methionine sulfoxide reductase (RefSeq) low > 64
Brevundimonas sp. GW460-12-10-14-LB2 0.14 A4249_RS03825 MATE family efflux transporter 0.60 A4249_RS01745 peptide-methionine (S)-S-oxide reductase MsrA low > 48
Azospirillum brasilense Sp245 0.14 AZOBR_RS15325 multidrug transporter 0.54 AZOBR_RS12845 methionine sulfoxide reductase A low > 97
Caulobacter crescentus NA1000 0.13 CCNA_02099 Na+ driven multidrug efflux pump 0.56 CCNA_01046 peptide methionine sulfoxide reductase msrA low > 66
Caulobacter crescentus NA1000 Δfur 0.13 CCNA_02099 Na+ driven multidrug efflux pump 0.56 CCNA_01046 peptide methionine sulfoxide reductase msrA low > 67
Azospirillum sp. SherDot2 0.12 MPMX19_01223 Multidrug resistance protein NorM 0.55 MPMX19_02247 Peptide methionine sulfoxide reductase MsrA low > 112

Not shown: 53 genomes with orthologs for CSW01_07735 only; 3 genomes with orthologs for CSW01_12910 only