| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_09950 | | signal peptide peptidase SppA | 1.0 | CSW01_05940 | | anthranilate phosphoribosyltransferase | 0.67 | 6 |
| Dickeya dadantii 3937 | 0.46 | DDA3937_RS10290 | | signal peptide peptidase SppA | 0.63 | DDA3937_RS10475 | | anthranilate phosphoribosyltransferase | low | > 74 |
| Dickeya dianthicola 67-19 | 0.46 | HGI48_RS10300 | | signal peptide peptidase SppA | 0.63 | HGI48_RS10475 | | anthranilate phosphoribosyltransferase | low | > 71 |
| Dickeya dianthicola ME23 | 0.46 | DZA65_RS10775 | | signal peptide peptidase SppA | 0.63 | DZA65_RS10955 | | anthranilate phosphoribosyltransferase | low | > 75 |
| Serratia liquefaciens MT49 | 0.45 | IAI46_14325 | | signal peptide peptidase SppA | 0.60 | IAI46_14030 | | anthranilate phosphoribosyltransferase | low | > 87 |
| Rahnella sp. WP5 | 0.43 | EX31_RS06305 | | signal peptide peptidase SppA | 0.66 | EX31_RS09965 | | anthranilate phosphoribosyltransferase | low | > 89 |
| Shewanella sp. ANA-3 | 0.43 | Shewana3_1964 | | signal peptide peptidase SppA, 67K type (RefSeq) | 0.48 | Shewana3_1518 | trpD | anthranilate phosphoribosyltransferase (RefSeq) | 0.42 | 59 |
| Shewanella oneidensis MR-1 | 0.42 | SO2420 | sppA | signal peptide peptidase SppA, 67K type (NCBI ptt file) | 0.49 | SO3021 | trpD | anthranilate phosphoribosyltransferase (NCBI ptt file) | low | > 76 |
| Erwinia amylovora T8 | 0.42 | OLJFJH_13245 | | signal peptide peptidase SppA | 0.65 | OLJFJH_13485 | | Anthranilate phosphoribosyltransferase | low | > 58 |
| Pantoea agglomerans CFBP13505 P0401 | 0.42 | PagCFBP13505_RS02805 | | signal peptide peptidase SppA | 0.66 | PagCFBP13505_RS07005 | | anthranilate phosphoribosyltransferase | low | > 74 |
| Pantoea sp. MT58 | 0.42 | IAI47_08970 | | signal peptide peptidase SppA | 0.63 | IAI47_09180 | | anthranilate phosphoribosyltransferase | low | > 76 |
| Erwinia tracheiphila HP pepo 2.2 | 0.42 | IJEDHG_22640 | sppA | signal peptide peptidase SppA | 0.61 | IJEDHG_23500 | | Anthranilate phosphoribosyltransferase | low | > 61 |
| Shewanella loihica PV-4 | 0.41 | Shew_1941 | | signal peptide peptidase SppA, 67K type (RefSeq) | 0.50 | Shew_2253 | | anthranilate phosphoribosyltransferase (RefSeq) | low | > 60 |
| Alteromonas macleodii MIT1002 | 0.40 | MIT1002_01840 | | Protease 4 | 0.54 | MIT1002_01428 | | Anthranilate synthase component II | low | > 70 |
| Shewanella amazonensis SB2B | 0.40 | Sama_1723 | | signal peptide peptidase SppA, 67K type (RefSeq) | 0.48 | Sama_2131 | trpD | anthranilate phosphoribosyltransferase (RefSeq) | low | > 62 |
| Kangiella aquimarina DSM 16071 | 0.39 | B158DRAFT_1578 | | signal peptide peptidase SppA, 67K type | 0.46 | B158DRAFT_2427 | | anthranilate phosphoribosyltransferase | low | > 40 |
| Lysobacter sp. OAE881 | 0.30 | ABIE51_RS02175 | | signal peptide peptidase SppA | 0.30 | ABIE51_RS04180 | | anthranilate phosphoribosyltransferase | low | > 62 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.29 | Xcc-8004.4759.1 | | protease IV | 0.30 | Xcc-8004.621.1 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | low | > 74 |
| Dyella japonica UNC79MFTsu3.2 | 0.29 | ABZR86_RS12520 | | signal peptide peptidase SppA | 0.31 | ABZR86_RS12070 | | anthranilate phosphoribosyltransferase | low | > 74 |
| Rhodanobacter denitrificans MT42 | 0.28 | LRK55_RS10795 | | signal peptide peptidase SppA | 0.31 | LRK55_RS11295 | | anthranilate phosphoribosyltransferase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.28 | LRK54_RS11090 | | signal peptide peptidase SppA | 0.31 | LRK54_RS11565 | | anthranilate phosphoribosyltransferase | low | > 59 |
| Sphingobium sp. HT1-2 | 0.28 | GFF1301 | | Signal peptide peptidase SppA (protease 4) | 0.24 | GFF3537 | | Anthranilate phosphoribosyltransferase (EC 2.4.2.18) | low | > 95 |
| Sphingomonas koreensis DSMZ 15582 | 0.27 | Ga0059261_1351 | | signal peptide peptidase SppA, 67K type | 0.24 | Ga0059261_0929 | | anthranilate phosphoribosyltransferase | low | > 68 |
| Parabacteroides merdae CL09T00C40 | 0.25 | HMPREF1078_RS05290 | | signal peptide peptidase SppA | 0.27 | HMPREF1078_RS00135 | | anthranilate phosphoribosyltransferase | low | > 61 |
| Bacteroides stercoris CC31F | 0.25 | HMPREF1181_RS07630 | | signal peptide peptidase SppA | 0.27 | HMPREF1181_RS15335 | | anthranilate phosphoribosyltransferase | low | > 56 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.24 | BT1879 | | protease IV (NCBI ptt file) | 0.28 | BT0530 | | anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) | low | > 81 |
| Cellulophaga baltica 18 | 0.24 | M666_RS07935 | | signal peptide peptidase SppA | 0.28 | M666_RS09080 | | anthranilate phosphoribosyltransferase | low | > 67 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.24 | Echvi_2783 | | signal peptide peptidase SppA, 67K type | 0.29 | Echvi_2507 | | anthranilate phosphoribosyltransferase | — | — |
| Bacteroides ovatus ATCC 8483 | 0.24 | BACOVA_02940 | | signal peptide peptidase SppA, 67K type | 0.28 | BACOVA_03782 | | anthranilate phosphoribosyltransferase | low | > 96 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.23 | CA264_02220 | | signal peptide peptidase SppA | 0.26 | CA264_05065 | | anthranilate phosphoribosyltransferase | low | > 74 |
| Phocaeicola dorei CL03T12C01 | 0.23 | ABI39_RS07925 | | signal peptide peptidase SppA | 0.27 | ABI39_RS21060 | | anthranilate phosphoribosyltransferase | low | > 72 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.23 | ABZR88_RS13925 | | signal peptide peptidase SppA | 0.28 | ABZR88_RS10675 | | anthranilate phosphoribosyltransferase | — | — |
| Phocaeicola vulgatus CL09T03C04 | 0.22 | HMPREF1058_RS12895 | | signal peptide peptidase SppA | 0.26 | HMPREF1058_RS07185 | | anthranilate phosphoribosyltransferase | low | > 67 |
| Synechocystis sp000284455 PCC 6803 | 0.22 | SGL_RS07865 | | signal peptide peptidase SppA | 0.33 | SGL_RS07485 | | anthranilate phosphoribosyltransferase | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.22 | CA265_RS04415 | | signal peptide peptidase SppA | 0.27 | CA265_RS05010 | | anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) | low | > 88 |
| Caulobacter crescentus NA1000 | 0.17 | CCNA_00976 | | signal peptide peptidase A | 0.36 | CCNA_01975 | | anthranilate phosphoribosyltransferase | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.17 | CCNA_00976 | | signal peptide peptidase A | 0.36 | CCNA_01975 | | anthranilate phosphoribosyltransferase | low | > 67 |
| Azospirillum brasilense Sp245 | 0.16 | AZOBR_RS10750 | | protease IV | 0.36 | AZOBR_RS07455 | | anthranilate phosphoribosyltransferase | low | > 97 |
| Magnetospirillum magneticum AMB-1 | 0.16 | AMB_RS08065 | | serine protease | 0.33 | AMB_RS14410 | | anthranilate phosphoribosyltransferase | — | — |
| Rhodospirillum rubrum S1H | 0.16 | Rru_A2621 | | Peptidase S49 (NCBI) | 0.33 | Rru_A1896 | | Anthranilate phosphoribosyl transferase (NCBI) | low | > 58 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.16 | A4249_RS01460 | | signal peptide peptidase SppA | 0.36 | A4249_RS06170 | | anthranilate phosphoribosyltransferase | — | — |
| Azospirillum sp. SherDot2 | 0.16 | MPMX19_00798 | | Protease 4 | 0.36 | MPMX19_01015 | | Anthranilate phosphoribosyltransferase | low | > 112 |
Not shown: 23 genomes with orthologs for CSW01_09950 only; 57 genomes with orthologs for CSW01_05940 only