Conservation of cofitness between BWI76_RS19375 and BWI76_RS23985 in Klebsiella michiganensis M5al

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 1.0 BWI76_RS23985 erythrose-4-phosphate dehydrogenase 0.24 12
Escherichia coli ECRC98 0.93 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 JDDGAC_23015 epd erythrose-4-phosphate dehydrogenase low > 86
Escherichia coli ECRC101 0.93 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 MCAODC_09905 epd erythrose-4-phosphate dehydrogenase low > 87
Escherichia coli ECRC100 0.93 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 OKFHMN_19385 epd erythrose-4-phosphate dehydrogenase low > 80
Escherichia coli ECRC102 0.93 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 NIAGMN_17150 epd erythrose-4-phosphate dehydrogenase — —
Escherichia coli ECRC99 0.93 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 KEDOAH_08755 epd erythrose-4-phosphate dehydrogenase — —
Escherichia coli BW25113 0.93 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.93 b2927 epd D-erythrose 4-phosphate dehydrogenase (NCBI) low > 76
Escherichia coli ECOR27 0.93 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 NOLOHH_11295 epd erythrose-4-phosphate dehydrogenase low > 75
Escherichia coli ECRC62 0.93 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 BNILDI_09835 epd erythrose-4-phosphate dehydrogenase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.93 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.93 OHPLBJKB_00789 D-erythrose-4-phosphate dehydrogenase low > 73
Escherichia fergusonii Becca 0.92 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.93 EFB2_00979 D-erythrose-4-phosphate dehydrogenase low > 86
Escherichia coli BL21 0.92 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.93 ECD_02758 D-erythrose 4-phosphate dehydrogenase 0.37 50
Escherichia coli ECOR38 0.92 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 HEPCGN_18695 epd erythrose-4-phosphate dehydrogenase low > 87
Escherichia coli Nissle 1917 0.91 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 ECOLIN_RS16265 erythrose-4-phosphate dehydrogenase — —
Enterobacter sp. TBS_079 0.90 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.93 MPMX20_03779 D-erythrose-4-phosphate dehydrogenase 0.30 79
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.93 EX28DRAFT_2973 erythrose-4-phosphate dehydrogenase low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.93 GFF3022 D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72) low > 78
Pectobacterium carotovorum WPP14 0.79 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.84 HER17_RS02685 erythrose-4-phosphate dehydrogenase low > 75
Serratia liquefaciens MT49 0.77 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.84 IAI46_21015 erythrose-4-phosphate dehydrogenase low > 86
Rahnella sp. WP5 0.77 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.82 EX31_RS21405 erythrose-4-phosphate dehydrogenase low > 89
Dickeya dianthicola 67-19 0.76 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.83 HGI48_RS18445 erythrose-4-phosphate dehydrogenase low > 71
Dickeya dadantii 3937 0.76 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.83 DDA3937_RS18520 erythrose-4-phosphate dehydrogenase low > 74
Dickeya dianthicola ME23 0.76 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.83 DZA65_RS19580 erythrose-4-phosphate dehydrogenase low > 75
Erwinia tracheiphila SCR3 0.75 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.82 LU632_RS05535 epd erythrose-4-phosphate dehydrogenase low > 74
Pantoea sp. MT58 0.75 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.84 IAI47_03685 erythrose-4-phosphate dehydrogenase low > 76
Paraburkholderia sabiae LMG 24235 0.54 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.54 QEN71_RS27005 type I glyceraldehyde-3-phosphate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.54 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase 0.53 H281DRAFT_06315 glyceraldehyde-3-phosphate dehydrogenase (NAD+) — —
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS12250 phosphomethylpyrimidine kinase 0.53 BPHYT_RS16835 glyceraldehyde-3-phosphate dehydrogenase — —
Paraburkholderia graminis OAS925 0.50 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.53 ABIE53_003536 glyceraldehyde 3-phosphate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.48 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.48 TX73_004865 type I glyceraldehyde-3-phosphate dehydrogenase — —
Castellaniella sp019104865 MT123 0.44 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.52 ABCV34_RS15455 type I glyceraldehyde-3-phosphate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.72 CSW01_02530 D-erythrose-4-phosphate dehydrogenase low > 62
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.51 ABZR86_RS18615 type I glyceraldehyde-3-phosphate dehydrogenase — —
Dechlorosoma suillum PS 0.24 Dsui_0662 phosphomethylpyrimidine kinase 0.47 Dsui_1558 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.51 PFLU_RS28090 erythrose-4-phosphate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.24 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.51 PFLU_RS28090 erythrose-4-phosphate dehydrogenase — —
Pseudomonas simiae WCS417 0.23 PS417_24600 hydrogenase 0.51 PS417_26435 glyceraldehyde-3-phosphate dehydrogenase — —
Pseudomonas putida KT2440 0.22 PP_4782 Phosphomethylpyrimidine kinase 0.52 PP_4964 D-erythrose 4-phosphate dehydrogenase low > 96
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.52 PfGW456L13_1065 D-erythrose-4-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E3 0.22 AO353_06350 hydrogenase 0.52 AO353_07950 glyceraldehyde-3-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.22 AO356_15435 hydrogenase 0.53 AO356_13685 glyceraldehyde-3-phosphate dehydrogenase low > 104
Pseudomonas stutzeri RCH2 0.21 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.51 Psest_0329 erythrose-4-phosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.21 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.52 Psyr_4791 D-erythrose-4-phosphate dehydrogenase 0.44 52
Pseudomonas syringae pv. syringae B728a 0.21 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.52 Psyr_4791 D-erythrose-4-phosphate dehydrogenase — —
Acinetobacter radioresistens SK82 0.21 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.45 MPMX26_01087 D-erythrose-4-phosphate dehydrogenase — —
Pseudomonas sp. RS175 0.20 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.53 PFR28_04187 D-erythrose-4-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.18 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.52 Pf1N1B4_2398 D-erythrose-4-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.18 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.52 Pf6N2E2_4656 D-erythrose-4-phosphate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.18 HSERO_RS02135 phosphomethylpyrimidine kinase 0.51 HSERO_RS07125 glyceraldehyde-3-phosphate dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.17 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.47 PGA1_c27490 glyceraldehyde-3-phosphate dehydrogenase Gap — —

Not shown: 39 genomes with orthologs for BWI76_RS19375 only; 8 genomes with orthologs for BWI76_RS23985 only