Conservation of cofitness between Atu2796 and Atu1542 in Agrobacterium fabrum C58

39 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu2796 precorrin-4 C11-methyltransferase 1.0 Atu1542 Bifunctional adenosylcobalamin biosynthesis protein cobP 0.68 9
Sinorhizobium meliloti 1021 0.76 SMc03187 precorrin-4 C(11)-methyltransferase 0.61 SMc04305 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Rhizobium sp. OAE497 0.76 ABIE40_RS20430 precorrin-4 C(11)-methyltransferase 0.60 ABIE40_RS11165 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.80 55
Rhodopseudomonas palustris CGA009 0.71 TX73_010740 precorrin-4 C(11)-methyltransferase 0.43 TX73_003695 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Bosea sp. OAE506 0.67 ABIE41_RS01830 precorrin-4 C(11)-methyltransferase 0.47 ABIE41_RS01770 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Azospirillum sp. SherDot2 0.65 MPMX19_05565 Precorrin-4 C(11)-methyltransferase 0.51 MPMX19_01023 Bifunctional adenosylcobalamin biosynthesis protein CobP — —
Phaeobacter inhibens DSM 17395 0.60 PGA1_c08090 precorrin-4 C(11)-methyltransferase CobM 0.45 PGA1_c26670 bifunctional adenosylcobalamin biosynthesis protein CobP — —
Rhodospirillum rubrum S1H 0.55 Rru_A3384 Precorrin-4 C11-methyltransferase region (NCBI) 0.42 Rru_A0670 Cobalbumin biosynthesis enzyme (NCBI) 0.70 19
Magnetospirillum magneticum AMB-1 0.53 AMB_RS02645 precorrin-4 C(11)-methyltransferase 0.49 AMB_RS22385 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Dinoroseobacter shibae DFL-12 0.50 Dshi_0176 precorrin-4 C11-methyltransferase (RefSeq) 0.43 Dshi_2979 Adenosylcobinamide-phosphateguanylyltransferase (RefSeq) — —
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS08780 precorrin-4 C(11)-methyltransferase 0.42 QEN71_RS25100 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 153
Pseudomonas simiae WCS417 0.46 PS417_12325 precorrin-4 C11-methyltransferase 0.40 PS417_20035 adenosylcobinamide kinase 0.53 4
Pseudomonas sp. RS175 0.46 PFR28_01372 Precorrin-4 C(11)-methyltransferase 0.40 PFR28_03203 Bifunctional adenosylcobalamin biosynthesis protein CobP 0.46 7
Pseudomonas fluorescens SBW25-INTG 0.46 PFLU_RS13015 precorrin-4 C(11)-methyltransferase 0.37 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.62 11
Pseudomonas fluorescens SBW25 0.46 PFLU_RS13015 precorrin-4 C(11)-methyltransferase 0.37 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.75 85
Ralstonia solanacearum UW163 0.45 UW163_RS18655 precorrin-4 C(11)-methyltransferase 0.37 UW163_RS09220 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS20520 precorrin-4 C(11)-methyltransferase 0.37 RALBFv3_RS04450 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 76
Ralstonia solanacearum PSI07 0.45 RPSI07_RS02220 precorrin-4 C(11)-methyltransferase 0.37 RPSI07_RS12920 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 81
Mycobacterium tuberculosis H37Rv 0.45 Rv2071c Precorrin-3 methylase CobM (precorrin-4 C11-methyltransferase) 0.28 Rv0254c Probable bifunctional cobalamin biosynthesis protein CobU: cobinamide kinase + cobinamide phosphate guanylyltransferase — —
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_02858 precorrin-4 C11-methyltransferase /precorrin-2 C20-methyltransferase 0.39 H281DRAFT_00145 adenosylcobinamide kinase /adenosylcobinamide-phosphate guanylyltransferase — —
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS26660 precorrin-4 C11-methyltransferase 0.42 BPHYT_RS04895 adenosylcobinamide kinase low > 109
Pseudomonas putida KT2440 0.45 PP_3410 Precorrin-4 C(11)-methyltransferase 0.39 PP_1678 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase — —
Ralstonia solanacearum GMI1000 0.45 RS_RS20085 precorrin-4 C(11)-methyltransferase 0.37 RS_RS12005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 80
Pseudomonas fluorescens FW300-N2C3 0.44 AO356_00530 precorrin-4 C11-methyltransferase 0.40 AO356_19165 adenosylcobinamide kinase 0.51 11
Pseudomonas fluorescens GW456-L13 0.44 PfGW456L13_2850 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) 0.41 PfGW456L13_4237 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.69 11
Pseudomonas fluorescens FW300-N2E2 0.44 Pf6N2E2_2065 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) 0.41 Pf6N2E2_5743 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.51 7
Pseudomonas fluorescens FW300-N1B4 0.44 Pf1N1B4_5658 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) 0.41 Pf1N1B4_3712 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.66 1
Paraburkholderia graminis OAS925 0.44 ABIE53_005936 precorrin-4/cobalt-precorrin-4 C11-methyltransferase 0.38 ABIE53_001254 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.88 9
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_21630 precorrin-4 C11-methyltransferase 0.41 AO353_02610 adenosylcobinamide kinase 0.51 11
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_3020 precorrin-4 C11-methyltransferase 0.41 Psyr_3675 adenosylcobinamide kinase low > 86
Pseudomonas sp. S08-1 0.44 OH686_05035 precorrin-4 C11-methyltransferase 0.43 OH686_04960 Adenosylcobinamide kinase / Adenosylcobinamide-phosphate guanylyltransferase low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_3020 precorrin-4 C11-methyltransferase 0.41 Psyr_3675 adenosylcobinamide kinase low > 86
Herbaspirillum seropedicae SmR1 0.43 HSERO_RS13280 precorrin-4 C11-methyltransferase 0.35 HSERO_RS13245 adenosylcobinamide kinase — —
Fusobacterium nucleatum SB010 0.43 HUW76_05335 precorrin-4 C(11)-methyltransferase 0.32 HUW76_05615 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Klebsiella michiganensis M5al 0.40 BWI76_RS23060 cobalt-precorrin-4 C(11)-methyltransferase 0.37 BWI76_RS23005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.39 GFF3956 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) 0.39 GFF3967 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) low > 78
Dechlorosoma suillum PS 0.33 Dsui_2959 precorrin-4 C11-methyltransferase 0.40 Dsui_0473 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 0.53 12
Synechococcus elongatus PCC 7942 0.32 Synpcc7942_1229 cobM precorrin-4 C11-methyltransferase 0.26 Synpcc7942_0990 cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Desulfovibrio vulgaris Miyazaki F 0.27 DvMF_1177 precorrin-4 C11-methyltransferase (RefSeq) 0.31 DvMF_3046 cobalbumin biosynthesis protein (RefSeq) 0.75 2
Hydrogenophaga sp. GW460-11-11-14-LB1 0.27 GFF4644 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) 0.38 GFF3979 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) — —

Not shown: 2 genomes with orthologs for Atu2796 only; 37 genomes with orthologs for Atu1542 only