| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Shewanella oneidensis MR-1 | 1.0 | SO1894 | | acetyl-CoA carboxylase, biotin carboxylase, putative (NCBI ptt file) | 1.0 | SO2191 | metC | cystathionine beta-lyase (NCBI ptt file) | 0.40 | 18 |
| Shewanella sp. ANA-3 | 0.93 | Shewana3_1669 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit (RefSeq) | 0.95 | Shewana3_2414 | | cystathionine beta-lyase (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.76 | Shew_2573 | | carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) | 0.82 | Shew_1789 | | cystathionine beta-lyase (RefSeq) | low | > 60 |
| Shewanella amazonensis SB2B | 0.68 | Sama_1359 | | 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) | 0.83 | Sama_2008 | | cystathionine beta-lyase (RefSeq) | low | > 62 |
| Azospirillum sp. SherDot2 | 0.45 | MPMX19_03940 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.42 | MPMX19_01339 | | Cystathionine beta-lyase MetC | low | > 112 |
| Azospirillum brasilense Sp245 | 0.45 | AZOBR_RS22285 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.45 | AZOBR_RS08650 | | cystathionine beta-lyase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.44 | RALBFv3_RS10460 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.38 | RALBFv3_RS20555 | | cystathionine beta-lyase | low | > 76 |
| Ralstonia solanacearum UW163 | 0.44 | UW163_RS03120 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.38 | UW163_RS18620 | | cystathionine beta-lyase | — | — |
| Ralstonia solanacearum PSI07 | 0.44 | RPSI07_RS22860 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.39 | RPSI07_RS02185 | | cystathionine beta-lyase | low | > 81 |
| Magnetospirillum magneticum AMB-1 | 0.43 | AMB_RS03465 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.48 | AMB_RS06585 | | cystathionine beta-lyase | low | > 64 |
| Ralstonia sp. UNC404CL21Col | 0.43 | ABZR87_RS06260 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.42 | ABZR87_RS11250 | | cystathionine beta-lyase | low | > 80 |
| Cupriavidus basilensis FW507-4G11 | 0.43 | RR42_RS26895 | | 3-methylcrotonyl-CoA carboxylase | 0.38 | RR42_RS31610 | | cystathionine beta-lyase | low | > 128 |
| Ralstonia solanacearum GMI1000 | 0.43 | RS_RS01300 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.34 | RS_RS08260 | | cystathionine beta-lyase | low | > 80 |
| Pseudomonas syringae pv. syringae B728a | 0.43 | Psyr_2467 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit | 0.39 | Psyr_0607 | | cystathionine beta-lyase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.43 | Psyr_2467 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit | 0.39 | Psyr_0607 | | cystathionine beta-lyase | low | > 86 |
| Pseudomonas fluorescens FW300-N2E3 | 0.43 | AO353_20335 | | 3-methylcrotonyl-CoA carboxylase | 0.46 | AO353_24330 | | cystathionine beta-lyase | low | > 101 |
| Acinetobacter baumannii LAC-4 | 0.43 | RR41_RS11115 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.24 | RR41_RS02145 | | PLP-dependent transferase | low | > 55 |
| Agrobacterium fabrum C58 | 0.43 | Atu3479 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.43 | Atu1575 | | cystathionine beta lyase | low | > 89 |
| Pseudomonas sp. SVBP6 | 0.43 | COO64_RS24740 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.45 | COO64_RS09240 | metC | cystathionine beta-lyase | low | > 93 |
| Herbaspirillum seropedicae SmR1 | 0.43 | HSERO_RS23460 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.35 | HSERO_RS14995 | | cystathionine beta-lyase | low | > 78 |
| Paraburkholderia sabiae LMG 24235 | 0.42 | QEN71_RS12855 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | QEN71_RS22165 | | cystathionine beta-lyase | low | > 153 |
| Burkholderia phytofirmans PsJN | 0.42 | BPHYT_RS23275 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.35 | BPHYT_RS09190 | | cystathionine beta-lyase | low | > 109 |
| Xanthobacter sp. DMC5 | 0.42 | GFF3791 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.48 | GFF1018 | | Cystathionine beta-lyase MetC | — | — |
| Acidovorax sp. GW101-3H11 | 0.41 | Ac3H11_3016 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.26 | Ac3H11_4146 | | Cystathionine beta-lyase (EC 4.4.1.8) | — | — |
| Acinetobacter radioresistens SK82 | 0.41 | MPMX26_00629 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.24 | MPMX26_02724 | | Cystathionine beta-lyase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.41 | H281DRAFT_01343 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit | 0.36 | H281DRAFT_00859 | | cystathionine beta-lyase | low | > 103 |
| Castellaniella sp019104865 MT123 | 0.41 | ABCV34_RS12350 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.34 | ABCV34_RS12385 | | PLP-dependent aspartate aminotransferase family protein | low | > 48 |
| Phaeobacter inhibens DSM 17395 | 0.39 | PGA1_c10330 | | methylcrotonoyl-CoA carboxylase subunit alpha | 0.27 | PGA1_c16720 | | putative pyridoxal phosphate-dependent transferase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.39 | GFF1711 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.42 | GFF5026 | | Cystathionine beta-lyase (EC 4.4.1.8) | low | > 90 |
| Variovorax sp. OAS795 | 0.38 | ABID97_RS25115 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.41 | ABID97_RS22430 | | cystathionine beta-lyase | low | > 91 |
| Variovorax sp. SCN45 | 0.38 | GFF2013 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.41 | GFF1749 | | Cystathionine beta-lyase (EC 4.4.1.8) | low | > 127 |
| Sinorhizobium meliloti 1021 | 0.38 | SM_b21124 | | 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) | 0.44 | SMc02117 | | cystathionine beta-lyase | low | > 103 |
| Rhodopseudomonas palustris CGA009 | 0.37 | TX73_013120 | | acetyl-CoA carboxylase biotin carboxylase subunit | 0.47 | TX73_013235 | | cystathionine beta-lyase | low | > 86 |
| Bosea sp. OAE506 | 0.36 | ABIE41_RS14850 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.33 | ABIE41_RS01480 | | cystathionine beta-lyase | low | > 77 |
| Sphingomonas koreensis DSMZ 15582 | 0.36 | Ga0059261_4056 | | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.53 | Ga0059261_1388 | | cystathionine beta-lyase, bacterial | low | > 68 |
| Rhodospirillum rubrum S1H | 0.36 | Rru_A1941 | | acyl-CoA carboxylase alpha chain (NCBI) | 0.46 | Rru_A1613 | | Cystathionine beta-lyase (NCBI) | low | > 58 |
| Rhizobium sp. OAE497 | 0.36 | ABIE40_RS20775 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.44 | ABIE40_RS08820 | | cystathionine beta-lyase | low | > 107 |
| Sphingobium sp. HT1-2 | 0.36 | GFF4876 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.52 | GFF585 | | Cystathionine beta-lyase (EC 4.4.1.8) | low | > 95 |
| Caulobacter crescentus NA1000 Δfur | 0.36 | CCNA_02250 | | methylcrotonyl-CoA carboxylase biotin-containing subunit | 0.38 | CCNA_01491 | | cystathionine beta-lyase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.36 | CCNA_02250 | | methylcrotonyl-CoA carboxylase biotin-containing subunit | 0.38 | CCNA_01491 | | cystathionine beta-lyase | low | > 66 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.35 | A4249_RS03810 | | biotin carboxylase N-terminal domain-containing protein | 0.31 | A4249_RS05585 | | cystathionine beta-lyase | low | > 48 |
Not shown: 33 genomes with orthologs for SO1894 only; 30 genomes with orthologs for SO2191 only