Conservation of cofitness between b3368 and b3770 in Escherichia coli BW25113

56 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.93 13
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00334 Siroheme synthase 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia coli BL21 1.00 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase 1.00 ECD_03648 branched-chain amino acid aminotransferase low > 60
Escherichia coli Nissle 1917 1.00 ECOLIN_RS19285 siroheme synthase CysG 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase low > 52
Escherichia coli ECRC98 1.00 JDDGAC_20810 cysG siroheme synthase CysG 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC99 1.00 KEDOAH_10960 cysG siroheme synthase CysG 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC102 1.00 NIAGMN_14950 cysG siroheme synthase CysG 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 1.00 MCAODC_07710 cysG siroheme synthase CysG 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 1.00 OKFHMN_17180 cysG siroheme synthase CysG 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase — —
Escherichia fergusonii Becca 1.00 EFB2_00454 Siroheme synthase 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Escherichia coli ECOR27 1.00 NOLOHH_08980 cysG siroheme synthase CysG 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase low > 57
Escherichia coli ECOR38 1.00 HEPCGN_16010 cysG siroheme synthase CysG 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia coli ECRC62 1.00 BNILDI_02540 cysG siroheme synthase CysG 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.98 GFF2902 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I 0.61 15
Enterobacter sp. TBS_079 0.89 MPMX20_04271 Siroheme synthase 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Klebsiella michiganensis M5al 0.88 BWI76_RS26055 siroheme synthase 0.97 BWI76_RS00970 branched chain amino acid aminotransferase low > 92
Pectobacterium carotovorum WPP14 0.72 HER17_RS01835 siroheme synthase CysG 0.90 HER17_RS01070 branched-chain amino acid transaminase low > 75
Rahnella sp. WP5 0.71 EX31_RS04680 uroporphyrinogen-III C-methyltransferase 0.90 EX31_RS15000 branched-chain amino acid transaminase low > 89
Serratia liquefaciens MT49 0.71 IAI46_23670 uroporphyrinogen-III C-methyltransferase 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Erwinia tracheiphila SCR3 0.53 LU632_RS06420 cysG siroheme synthase CysG 0.90 LU632_RS24405 branched-chain amino acid transaminase low > 74
Dickeya dianthicola 67-19 0.51 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase low > 71
Dickeya dadantii 3937 0.51 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.81 39
Pseudomonas stutzeri RCH2 0.51 Psest_2037 uroporphyrin-III C-methyltransferase 0.46 Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 67
Dickeya dianthicola ME23 0.50 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase 0.91 DZA65_RS21340 branched-chain amino acid transaminase 0.71 46
Pantoea sp. MT58 0.50 IAI47_04175 uroporphyrinogen-III C-methyltransferase 0.91 IAI47_01030 branched-chain amino acid transaminase 0.83 32
Pseudomonas sp. RS175 0.49 PFR28_02603 Siroheme synthase 0.21 PFR28_02449 putative branched-chain-amino-acid aminotransferase low > 88
Pseudomonas syringae pv. syringae B728a 0.49 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme 0.67 39
Pseudomonas syringae pv. syringae B728a ΔmexB 0.49 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme 0.54 56
Pseudomonas fluorescens FW300-N2C3 0.49 AO356_22200 sirohydrochlorin ferrochelatase 0.21 AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 104
Pseudomonas fluorescens FW300-N1B4 0.49 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.22 Pf1N1B4_4476 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Pseudomonas fluorescens FW300-N2E2 0.49 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.21 Pf6N2E2_477 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 103
Pseudomonas fluorescens GW456-L13 0.49 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.27 PfGW456L13_4923 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Kangiella aquimarina DSM 16071 0.49 B158DRAFT_2163 uroporphyrin-III C-methyltransferase 0.20 B158DRAFT_0078 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase low > 40
Pseudomonas fluorescens FW300-N2E3 0.49 AO353_27625 sirohydrochlorin ferrochelatase 0.20 AO353_26655 branched-chain amino acid aminotransferase — —
Pseudomonas fluorescens SBW25 0.48 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Pseudomonas simiae WCS417 0.48 PS417_16465 sirohydrochlorin ferrochelatase 0.21 PS417_17565 branched-chain amino acid aminotransferase low > 88
Pseudomonas putida KT2440 0.47 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase 0.19 PP_3511 Branched-chain-amino-acid aminotransferase 0.77 21
Acinetobacter radioresistens SK82 0.45 MPMX26_00706 Siroheme synthase 0.40 MPMX26_00445 Branched-chain-amino-acid aminotransferase — —
Pseudomonas sp. S08-1 0.45 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase 0.46 OH686_09695 branched-chain amino acid aminotransferase low > 80
Alteromonas macleodii MIT1002 0.45 MIT1002_00665 Siroheme synthase 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 — —
Dyella japonica UNC79MFTsu3.2 0.44 ABZR86_RS05880 siroheme synthase CysG 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.87 31
Lysobacter sp. OAE881 0.43 ABIE51_RS15855 siroheme synthase CysG 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Castellaniella sp019104865 MT123 0.40 ABCV34_RS00210 siroheme synthase CysG 0.45 ABCV34_RS07930 branched-chain amino acid transaminase low > 48
Rhodanobacter sp. FW510-T8 0.40 OKGIIK_05980 cysG siroheme synthase CysG 0.56 OKGIIK_11840 ilvE branched-chain amino acid transaminase low > 52
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS00910 siroheme synthase CysG 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Rhodanobacter denitrificans MT42 0.37 LRK55_RS00685 siroheme synthase CysG 0.56 LRK55_RS11755 branched-chain amino acid transaminase low > 63
Agrobacterium fabrum C58 0.33 Atu3899 siroheme synthase 0.18 Atu0871 branched-chain-amino-acid aminotransferase low > 89
Sinorhizobium meliloti 1021 0.32 SMc01053 siroheme synthase 0.21 SMc02896 branched-chain amino acid aminotransferase low > 103
Rhizobium sp. OAE497 0.31 ABIE40_RS09140 siroheme synthase CysG 0.19 ABIE40_RS22240 branched-chain amino acid aminotransferase low > 107
Brevundimonas sp. GW460-12-10-14-LB2 0.31 A4249_RS09675 siroheme synthase CysG 0.27 A4249_RS09820 branched-chain amino acid aminotransferase — —
Rhodopseudomonas palustris CGA009 0.30 TX73_021850 siroheme synthase CysG 0.18 TX73_022650 branched-chain amino acid aminotransferase — —
Rhodospirillum rubrum S1H 0.27 Rru_A1933 Uroporphyrin-III C-methyltransferase (NCBI) 0.32 Rru_A2223 Branched-chain amino acid aminotransferase I (NCBI) low > 58
Dinoroseobacter shibae DFL-12 0.27 Dshi_1155 uroporphyrin-III C-methyltransferase (RefSeq) 0.26 Dshi_3301 branched-chain amino acid aminotransferase (RefSeq) — —
Bosea sp. OAE506 0.26 ABIE41_RS15910 siroheme synthase CysG 0.28 ABIE41_RS11405 branched-chain amino acid aminotransferase — —
Mycobacterium tuberculosis H37Rv 0.20 Rv2847c Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase 0.19 Rv2210c Branched-chain amino acid transaminase IlvE — —

Not shown: 0 genomes with orthologs for b3368 only; 46 genomes with orthologs for b3770 only