Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4413 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | strong | 100 | 100 |
o | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS01045 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 41 | 96 |
o | Bacteroides stercoris CC31F | HMPREF1181_RS15695 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 40 | 96 |
o | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS16250 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | strong | 40 | 97 |
o | Phocaeicola dorei CL03T12C01 | ABI39_RS12140 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | strong | 40 | 97 |
o | Bacteroides ovatus ATCC 8483 | BACOVA_05551 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | strong | 39 | 96 |
o | Bacteroides thetaiotaomicron VPI-5482 | BT4701 | | 2-oxoglutarate decarboxylase and 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (NCBI ptt file) | no data | 39 | 96 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS11995 | | thiamine pyrophosphate-binding protein | insig. | 35 | 95 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS11070 | | thiamine pyrophosphate-binding protein | cofit | 34 | 93 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08835 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | no data | 31 | 94 |
o | Shewanella loihica PV-4 | Shew_1408 | | thiamine pyrophosphate binding domain-containing protein (RefSeq) | no data | 31 | 93 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2344 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | no data | 30 | 93 |
| Synechococcus elongatus PCC 7942 | Synpcc7942_1435 | menD | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase | no data | 24 | 93 |
| Shewanella sp. ANA-3 | Shewana3_3965 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase (RefSeq) | strong | 26 | 80 |
| Shewanella oneidensis MR-1 | SO4573 | menD | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase (NCBI ptt file) | strong | 26 | 80 |
| Shewanella loihica PV-4 | Shew_3599 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase (RefSeq) | strong | 27 | 80 |
| Escherichia coli ECOR38 | HEPCGN_22150 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | cofit | 27 | 80 |
| Escherichia coli BL21 | ECD_02191 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; SEPHCHC synthase | insig. | 26 | 88 |
| Escherichia coli ECOR27 | NOLOHH_14560 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | cofit | 26 | 88 |
| Escherichia coli ECRC62 | BNILDI_13475 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 26 | 88 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01446 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | insig. | 26 | 88 |
| Escherichia coli BW25113 | b2264 | menD | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase (NCBI) | sig. | 26 | 88 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1870 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase (EC 2.2.1.9) | insig. | 25 | 88 |
| Escherichia coli ECRC101 | OKFHMN_22935 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 27 | 80 |
| Escherichia coli ECRC101 | MCAODC_13975 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 27 | 80 |
| Escherichia coli ECRC102 | NIAGMN_20705 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 27 | 80 |
| Escherichia coli ECRC98 | JDDGAC_26900 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | no data | 27 | 80 |
| Escherichia coli ECRC99 | KEDOAH_05260 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | no data | 27 | 80 |
| Escherichia fergusonii Becca | EFB2_01591 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | insig. | 26 | 80 |
| Escherichia coli Nissle 1917 | ECOLIN_RS13185 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 26 | 80 |
| Pectobacterium carotovorum WPP14 | HER17_RS15555 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 25 | 93 |
| Klebsiella michiganensis M5al | BWI76_RS20075 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | sig. | 25 | 80 |
| Shewanella amazonensis SB2B | Sama_3460 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase (RefSeq) | strong | 25 | 92 |
| Enterobacter sp. TBS_079 | MPMX20_03200 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | insig. | 26 | 80 |
| Erwinia tracheiphila SCR3 | LU632_RS08105 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 25 | 88 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_09860 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | cofit | 25 | 80 |
| Enterobacter asburiae PDN3 | EX28DRAFT_0340 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | insig. | 23 | 94 |
| Serratia liquefaciens MT49 | IAI46_17560 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 25 | 79 |
| Rahnella sp. WP5 | EX31_RS19355 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 25 | 81 |
| Dickeya dadantii 3937 | DDA3937_RS05915 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 23 | 93 |
| Dickeya dianthicola 67-19 | HGI48_RS05960 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 23 | 93 |
| Dickeya dianthicola ME23 | DZA65_RS06295 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 23 | 93 |
| Dechlorosoma suillum PS | Dsui_2922 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 31 | 40 |
| Mycobacterium tuberculosis H37Rv | Rv0555 | | Probable bifunctional menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) + 2-oxoglutarate decarboxylase (alpha-ketoglutarate decarboxylase) (KDC) | no data | 33 | 27 |
| Mycobacterium tuberculosis H37Rv | Rv0555 | | Probable bifunctional menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) + 2-oxoglutarate decarboxylase (alpha-ketoglutarate decarboxylase) (KDC) | no data | 30 | 29 |
| Caulobacter crescentus NA1000 | CCNA_02185 | | acetolactate synthase large subunit | strong | 24 | 35 |
| Caulobacter crescentus NA1000 Δfur | CCNA_02185 | | acetolactate synthase large subunit | insig. | 24 | 35 |
| Dickeya dadantii 3937 | DDA3937_RS18170 | | acetolactate synthase large subunit | cofit | 23 | 38 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_0068 | | acetolactate synthase, large subunit (EC 2.2.1.6) | strong | 22 | 28 |
| Enterobacter asburiae PDN3 | EX28DRAFT_2393 | | Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] | insig. | 29 | 17 |
| Pantoea sp. MT58 | IAI47_07665 | | thiamine pyrophosphate-requiring protein | insig. | 25 | 33 |
| Dickeya dianthicola 67-19 | HGI48_RS18120 | | acetolactate synthase large subunit | insig. | 22 | 33 |
| Dechlorosoma suillum PS | Dsui_2922 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 26 | 31 |
| Dickeya dianthicola ME23 | DZA65_RS19270 | | acetolactate synthase large subunit | cofit | 22 | 33 |
| Phaeobacter inhibens DSM 17395 | PGA1_c12350 | | acetolactate synthase, catabolic | insig. | 23 | 25 |