| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sinorhizobium meliloti 1021 | 1.0 | SM_b20039 | | transcriptional regulator | 1.0 | SMa1131 | | Metallo-beta-lactamase superfamily protein | 0.24 | 12 |
| Pseudomonas sp. BP01 | 0.64 | JOY50_RS04420 | | PLP-dependent aminotransferase family protein | 0.18 | JOY50_RS16110 | | MBL fold metallo-hydrolase RNA specificity domain-containing protein | low | > 84 |
| Pseudomonas putida KT2440 | 0.63 | PP_2948 | | Transcriptional regulator, GntR family | 0.25 | PP_3291 | | Metallo-beta-lactamase family protein | low | > 96 |
| Dyella japonica UNC79MFTsu3.2 | 0.63 | ABZR86_RS04055 | | PLP-dependent aminotransferase family protein | 0.28 | ABZR86_RS04385 | | MBL fold metallo-hydrolase | low | > 74 |
| Azospirillum brasilense Sp245 | 0.59 | AZOBR_RS27565 | | GntR family transcriptional regulator | 0.45 | AZOBR_RS07000 | | beta-lactamase | low | > 97 |
| Castellaniella sp019104865 MT123 | 0.57 | ABCV34_RS15105 | | PLP-dependent aminotransferase family protein | 0.25 | ABCV34_RS06000 | | MBL fold metallo-hydrolase | low | > 48 |
| Azospirillum sp. SherDot2 | 0.57 | MPMX19_02820 | | HTH-type transcriptional regulator NorG | 0.45 | MPMX19_05334 | | hypothetical protein | low | > 112 |
| Dechlorosoma suillum PS | 0.36 | Dsui_0420 | | transcriptional regulator with HTH domain and aminotransferase domain | 0.29 | Dsui_1635 | | putative exonuclease of the beta-lactamase fold involved in RNA processing | low | > 51 |
| Pseudomonas aeruginosa PUPa3 | 0.36 | DQ20_RS49825 | | PLP-dependent aminotransferase family protein | 0.31 | DQ20_RS42220 | | MBL fold metallo-hydrolase | low | > 101 |
| Pseudomonas aeruginosa PA14 | 0.36 | IKLFDK_27035 | | GntR family transcriptional regulator | 0.31 | IKLFDK_18450 | | MBL fold metallo-hydrolase | low | > 98 |
| Pseudomonas aeruginosa MRSN321 | 0.36 | DY961_RS12300 | | PLP-dependent aminotransferase family protein | 0.31 | DY961_RS14910 | | MBL fold metallo-hydrolase | low | > 100 |
| Acidovorax sp. GW101-3H11 | 0.36 | Ac3H11_4178 | | Transcriptional regulator GabR of GABA utilization (GntR family with aminotransferase-like domain) | 0.25 | Ac3H11_1523 | | Metallo-beta-lactamase family protein, RNA-specific | low | > 79 |
| Burkholderia phytofirmans PsJN | 0.35 | BPHYT_RS15820 | | GntR family transcriptional regulator | 0.27 | BPHYT_RS27805 | | RNA-metabolising metallo-beta-lactamase | low | > 109 |
| Cupriavidus basilensis FW507-4G11 | 0.35 | RR42_RS01590 | | GntR family transcriptional regulator | 0.24 | RR42_RS09610 | | mRNA 3'-end processing factor | low | > 128 |
| Pseudomonas sp. RS175 | 0.34 | PFR28_01790 | | Histidinol-phosphate aminotransferase | 0.25 | PFR28_02316 | | Ribonuclease | low | > 88 |
| Pseudomonas fluorescens FW300-N2E2 | 0.34 | Pf6N2E2_684 | | Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) | 0.24 | Pf6N2E2_1519 | | Metallo-beta-lactamase family protein, RNA-specific | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.34 | AO356_24975 | | GntR family transcriptional regulator | 0.24 | AO356_23925 | | mRNA 3'-end processing factor | low | > 104 |
| Ralstonia sp. UNC404CL21Col | 0.34 | ABZR87_RS09835 | | PLP-dependent aminotransferase family protein | 0.25 | ABZR87_RS19990 | | MBL fold metallo-hydrolase | low | > 80 |
| Ralstonia solanacearum GMI1000 | 0.33 | RS_RS04895 | | PLP-dependent aminotransferase family protein | 0.25 | RS_RS00995 | | MBL fold metallo-hydrolase | low | > 80 |
| Variovorax sp. SCN45 | 0.33 | GFF6644 | | DNA-binding transcriptional regulator, MocR family / aminotransferase domain | 0.23 | GFF6952 | | Metallo-beta-lactamase family protein, RNA-specific | low | > 127 |
| Pseudomonas fluorescens FW300-N2E3 | 0.31 | AO353_01655 | | GntR family transcriptional regulator | 0.26 | AO353_19925 | | mRNA 3'-end processing factor | low | > 101 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.30 | GFF5390 | | Transcriptional regulator, GntR family domain / Aspartate aminotransferase (EC 2.6.1.1) | 0.26 | GFF3226 | | Metallo-beta-lactamase family protein, RNA-specific | low | > 90 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.29 | Psyr_4325 | | transcriptional regulator, GntR family | 0.16 | Psyr_3639 | | Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase | 0.51 | 6 |
| Pseudomonas syringae pv. syringae B728a | 0.29 | Psyr_4325 | | transcriptional regulator, GntR family | 0.16 | Psyr_3639 | | Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase | low | > 86 |
| Pseudomonas stutzeri RCH2 | 0.19 | Psest_1710 | | Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs | 0.27 | Psest_2869 | | Predicted exonuclease of the beta-lactamase fold involved in RNA processing | low | > 67 |
| Lysobacter sp. OAE881 | 0.19 | ABIE51_RS03870 | | PLP-dependent aminotransferase family protein | 0.25 | ABIE51_RS06640 | | MBL fold metallo-hydrolase | low | > 62 |
| Marinobacter adhaerens HP15 | 0.18 | HP15_1687 | | transcriptional regulator, GntR family with aminotransferase domain protein | 0.26 | HP15_2406 | | metallo-beta-lactamase family protein | low | > 73 |
| Shewanella sp. ANA-3 | 0.17 | Shewana3_0929 | | GntR family transcriptional regulator (RefSeq) | 0.27 | Shewana3_0537 | | aspartate kinase (RefSeq) | low | > 73 |
| Desulfovibrio vulgaris Miyazaki F | 0.16 | DvMF_2175 | | transcriptional regulator, GntR family with aminotransferase domain (RefSeq) | 0.31 | DvMF_0171 | | beta-lactamase domain protein (RefSeq) | low | > 51 |
Not shown: 54 genomes with orthologs for SM_b20039 only; 21 genomes with orthologs for SMa1131 only