| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sinorhizobium meliloti 1021 | 1.0 | SM_b20014 | | transcriptional regulator | 1.0 | SM_b20071 | | efflux protein | 0.22 | 18 |
| Agrobacterium fabrum C58 | 0.44 | Atu4373 | | LacI family transcriptional regulator | 0.88 | Atu4292 | | chloramphenicol resistance protein | low | > 89 |
| Dyella japonica UNC79MFTsu3.2 | 0.40 | ABZR86_RS01690 | | LacI family DNA-binding transcriptional regulator | 0.38 | ABZR86_RS18115 | | MFS transporter | low | > 74 |
| Rahnella sp. WP5 | 0.38 | EX31_RS14230 | | DNA-binding transcriptional regulator CytR | 0.56 | EX31_RS21215 | | MFS transporter | low | > 89 |
| Pantoea agglomerans CFBP13505 P0401 | 0.38 | PagCFBP13505_RS18480 | | DNA-binding transcriptional regulator CytR | 0.40 | PagCFBP13505_RS17120 | | MFS transporter | low | > 74 |
| Pantoea sp. MT58 | 0.38 | IAI47_00860 | | DNA-binding transcriptional regulator CytR | 0.40 | IAI47_03850 | | MFS transporter | low | > 76 |
| Enterobacter sp. TBS_079 | 0.36 | MPMX20_04535 | | HTH-type transcriptional repressor CytR | 0.56 | MPMX20_00893 | | Inner membrane transport protein YdhP | low | > 85 |
| Enterobacter asburiae PDN3 | 0.36 | EX28DRAFT_4407 | | Transcriptional regulators | 0.54 | EX28DRAFT_2686 | | Arabinose efflux permease | low | > 76 |
| Klebsiella michiganensis M5al | 0.36 | BWI76_RS00765 | | DNA-binding transcriptional regulator CytR | 0.53 | BWI76_RS05420 | | MFS transporter | low | > 92 |
| Escherichia coli Nissle 1917 | 0.36 | ECOLIN_RS22650 | | DNA-binding transcriptional regulator CytR | 0.30 | ECOLIN_RS09235 | | MFS transporter | low | > 55 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.36 | OHPLBJKB_04117 | | HTH-type transcriptional repressor CytR | 0.30 | OHPLBJKB_02068 | | Inner membrane transport protein YdhP | low | > 74 |
| Escherichia coli ECRC102 | 0.36 | NIAGMN_11480 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | NIAGMN_00665 | ydhP | Inner membrane transport protein YdhP | low | > 80 |
| Escherichia coli ECOR27 | 0.36 | NOLOHH_05870 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | NOLOHH_17920 | ydhP | Inner membrane transport protein YdhP | low | > 76 |
| Escherichia coli ECRC101 | 0.36 | MCAODC_04225 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | MCAODC_18010 | ydhP | Inner membrane transport protein YdhP | low | > 87 |
| Escherichia coli ECOR38 | 0.36 | HEPCGN_12370 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | HEPCGN_05785 | ydhP | Inner membrane transport protein YdhP | low | > 88 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.36 | GFF2316 | | Transcriptional (co)regulator CytR | 0.54 | GFF4040 | | Putative drug efflux protein | low | > 78 |
| Escherichia coli BW25113 | 0.36 | b3934 | cytR | DNA-binding transcriptional dual regulator (NCBI) | 0.30 | b1657 | ydhP | predicted transporter (NCBI) | low | > 76 |
| Escherichia coli ECRC100 | 0.36 | OKFHMN_13725 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | OKFHMN_27400 | ydhP | Inner membrane transport protein YdhP | low | > 79 |
| Escherichia coli ECRC98 | 0.36 | JDDGAC_17350 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | JDDGAC_01990 | ydhP | Inner membrane transport protein YdhP | low | > 87 |
| Escherichia coli ECRC62 | 0.36 | BNILDI_05660 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | BNILDI_16710 | ydhP | Inner membrane transport protein YdhP | low | > 75 |
| Serratia liquefaciens MT49 | 0.36 | IAI46_24560 | | DNA-binding transcriptional regulator CytR | 0.53 | IAI46_04120 | | MFS transporter | low | > 87 |
| Escherichia coli BL21 | 0.36 | ECD_03819 | | Anti-activator for CytR-CRP nucleoside utilization regulon | 0.30 | ECD_01627 | | putative MFS transporter, inner membrane protein | low | > 61 |
| Escherichia coli ECRC99 | 0.36 | KEDOAH_14435 | cytR | DNA-binding transcriptional regulator CytR | 0.30 | KEDOAH_00710 | ydhP | Inner membrane transport protein YdhP | — | — |
| Escherichia fergusonii Becca | 0.36 | EFB2_04684 | | HTH-type transcriptional repressor CytR | 0.30 | EFB2_02336 | | Inner membrane transport protein YdhP | low | > 86 |
| Erwinia amylovora T8 | 0.35 | OLJFJH_06075 | | DNA-binding transcriptional regulator CytR | 0.34 | OLJFJH_08870 | | MFS transporter | low | > 58 |
| Erwinia tracheiphila HP pepo 2.2 | 0.35 | IJEDHG_13000 | cytR | DNA-binding transcriptional regulator CytR | 0.24 | IJEDHG_09625 | | MFS transporter | low | > 61 |
| Klebsiella pneumoniae MKP103 | 0.35 | KDGMDA_09275 | | DNA-binding transcriptional regulator CytR | 0.53 | KDGMDA_13670 | | MFS sugar transporter | low | > 95 |
| Dickeya dianthicola 67-19 | 0.35 | HGI48_RS20445 | | DNA-binding transcriptional regulator CytR | 0.18 | HGI48_RS09295 | | sugar transporter | low | > 71 |
| Dickeya dianthicola ME23 | 0.35 | DZA65_RS21490 | | DNA-binding transcriptional regulator CytR | 0.18 | DZA65_RS09600 | | sugar transporter | low | > 75 |
| Dickeya dadantii 3937 | 0.35 | DDA3937_RS00930 | | DNA-binding transcriptional regulator CytR | 0.54 | DDA3937_RS03650 | | MFS transporter | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.34 | HER17_RS00865 | | DNA-binding transcriptional regulator CytR | 0.38 | HER17_RS09415 | | MFS transporter | low | > 75 |
| Paraburkholderia sabiae LMG 24235 | 0.34 | QEN71_RS25305 | | LacI family DNA-binding transcriptional regulator | 0.53 | QEN71_RS38940 | | MFS transporter | low | > 153 |
| Pseudomonas fluorescens FW300-N2C3 | 0.33 | AO356_22285 | | LacI family transcriptional regulator | 0.39 | AO356_13630 | | arabinose transporter permease | — | — |
| Alteromonas macleodii MIT1002 | 0.33 | MIT1002_00363 | | HTH-type transcriptional repressor CytR | 0.56 | MIT1002_01181 | | Inner membrane transport protein YdhP | low | > 70 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.33 | H281DRAFT_00103 | | transcriptional regulator, LacI family | 0.46 | H281DRAFT_04235 | | MFS transporter, DHA1 family, arabinose polymer transporter | low | > 103 |
| Sphingomonas koreensis DSMZ 15582 | 0.33 | Ga0059261_0555 | | transcriptional regulator, LacI family | 0.35 | Ga0059261_0886 | | Arabinose efflux permease | low | > 68 |
| Burkholderia phytofirmans PsJN | 0.33 | BPHYT_RS04680 | | LacI family transcriptional regulator | 0.45 | BPHYT_RS16520 | | major facilitator superfamily protein | low | > 109 |
| Pseudomonas fluorescens FW300-N2E2 | 0.32 | Pf6N2E2_322 | | Transcriptional regulator, LacI family | 0.39 | Pf6N2E2_4644 | | Arabinose efflux permease | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.32 | ABIE53_001217 | | LacI family repressor for deo operon, udp, cdd, tsx, nupC, and nupG | 0.47 | ABIE53_003475 | | DHA1 family inner membrane transport protein | low | > 113 |
| Pseudomonas sp. DMC3 | 0.32 | GFF1074 | | HTH-type transcriptional repressor CytR | 0.39 | GFF166 | | Inner membrane transport protein YdhP | low | > 89 |
| Pseudomonas sp. RS175 | 0.32 | PFR28_02584 | | HTH-type transcriptional repressor CytR | 0.39 | PFR28_04198 | | Inner membrane transport protein YdhP | low | > 88 |
| Shewanella amazonensis SB2B | 0.31 | Sama_0294 | | LacI family transcription regulator (RefSeq) | 0.52 | Sama_2390 | | putative transmembrane efflux transmembrane protein (RefSeq) | low | > 62 |
| Pseudomonas fluorescens FW300-N1B4 | 0.31 | Pf1N1B4_4095 | | Transcriptional regulator, LacI family | 0.52 | Pf1N1B4_2633 | | Putative drug efflux protein | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.26 | RR42_RS34650 | | LacI family transcriptional regulator | 0.55 | RR42_RS11400 | | MFS sugar transporter | low | > 128 |
| Lysobacter sp. OAE881 | 0.24 | ABIE51_RS10155 | | LacI family DNA-binding transcriptional regulator | 0.39 | ABIE51_RS06085 | | MFS transporter | low | > 62 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.24 | Xcc-8004.2362.1 | | Transcriptional regulator, LacI family | 0.43 | Xcc-8004.1806.1 | | MFS transporter | low | > 74 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.24 | GFF4454 | | Transcriptional regulator, LacI family | 0.57 | GFF2876 | | Putative drug efflux protein | low | > 90 |
| Sphingobium sp. HT1-2 | 0.24 | GFF1733 | | Transcriptional regulator, LacI family | 0.35 | GFF1837 | | Inner membrane transport protein YdhP | low | > 95 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.24 | A4249_RS03600 | | LacI family DNA-binding transcriptional regulator | 0.36 | A4249_RS02135 | | MFS transporter | low | > 48 |
| Bifidobacterium breve UCC2003 | 0.23 | BBR_RS19505 | | LacI family transcriptional regulator | 0.26 | BBR_RS17015 | | MFS transporter | low | > 34 |
| Shewanella sp. ANA-3 | 0.23 | Shewana3_3122 | | LacI family transcription regulator (RefSeq) | 0.55 | Shewana3_3597 | | major facilitator transporter (RefSeq) | low | > 73 |
Not shown: 12 genomes with orthologs for SM_b20014 only; 34 genomes with orthologs for SM_b20071 only