Conservation of cofitness between QEN71_RS24345 and QEN71_RS32005 in Paraburkholderia sabiae LMG 24235

44 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Paraburkholderia sabiae LMG 24235 1.0 QEN71_RS24345 DUF4118 domain-containing protein 1.0 QEN71_RS32005 tartrate dehydrogenase 0.41 8
Burkholderia phytofirmans PsJN 0.80 BPHYT_RS06460 histidine kinase 0.88 BPHYT_RS30235 tartrate dehydrogenase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.80 H281DRAFT_04532 two-component system, OmpR family, sensor histidine kinase KdpD 0.87 H281DRAFT_06345 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase low > 103
Paraburkholderia graminis OAS925 0.79 ABIE53_001556 two-component system sensor histidine kinase KdpD 0.88 ABIE53_005023 tartrate dehydrogenase/decarboxylase/D-malate dehydrogenase low > 113
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_28955 sensor protein KdpD 0.75 AO353_28225 tartrate dehydrogenase low > 101
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS18855 sensor protein KdpD 0.75 HSERO_RS07390 tartrate dehydrogenase low > 78
Cupriavidus basilensis FW507-4G11 0.46 RR42_RS00495 histidine kinase 0.66 RR42_RS02600 tartrate dehydrogenase low > 128
Ralstonia solanacearum UW163 0.44 UW163_RS04465 sensor histidine kinase KdpD 0.79 UW163_RS16880 tartrate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS09130 sensor histidine kinase KdpD 0.79 RALBFv3_RS16145 tartrate dehydrogenase low > 76
Ralstonia solanacearum PSI07 0.44 RPSI07_RS08140 sensor histidine kinase KdpD 0.80 RPSI07_RS07555 tartrate dehydrogenase 0.37 75
Ralstonia solanacearum GMI1000 0.43 RS_RS16960 sensor histidine kinase KdpD 0.80 RS_RS24845 tartrate dehydrogenase low > 80
Serratia liquefaciens MT49 0.43 IAI46_06165 two-component system sensor histidine kinase KdbD 0.74 IAI46_21025 tartrate dehydrogenase low > 86
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS04525 sensor histidine kinase KdpD 0.77 ABZR87_RS21505 tartrate dehydrogenase low > 80
Acidovorax sp. GW101-3H11 0.42 Ac3H11_2408 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.75 Ac3H11_3259 Tartrate dehydrogenase (EC 1.1.1.93) @ Tartrate decarboxylase (EC 4.1.1.73) @ D-malic enzyme (EC 1.1.1.83) low > 79
Escherichia coli BW25113 0.42 b0695 kdpD fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein (NCBI) 0.73 b1800 yeaU predicted dehydrogenase (NCBI) low > 76
Escherichia coli ECOR27 0.42 NOLOHH_23455 kdpD two-component system sensor histidine kinase KdpD 0.73 NOLOHH_17145 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 75
Escherichia coli ECOR38 0.42 HEPCGN_01160 kdpD two-component system sensor histidine kinase KdpD 0.73 HEPCGN_05015 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 87
Escherichia coli ECRC98 0.42 JDDGAC_10725 kdpD two-component system sensor histidine kinase KdpD 0.73 JDDGAC_01200 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 86
Escherichia coli ECRC62 0.42 BNILDI_21460 kdpD two-component system sensor histidine kinase KdpD 0.73 BNILDI_15930 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 75
Escherichia coli ECRC99 0.42 KEDOAH_20895 kdpD two-component system sensor histidine kinase KdpD 0.73 KEDOAH_01485 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase — —
Escherichia coli ECRC102 0.42 NIAGMN_05130 kdpD two-component system sensor histidine kinase KdpD 0.73 NIAGMN_01440 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase — —
Escherichia coli ECRC100 0.42 OKFHMN_07075 kdpD two-component system sensor histidine kinase KdpD 0.73 OKFHMN_26625 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 80
Escherichia coli ECRC101 0.42 MCAODC_26290 kdpD two-component system sensor histidine kinase KdpD 0.73 MCAODC_18785 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 87
Escherichia coli BL21 0.42 ECD_00652 fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein 0.73 ECD_01770 D-malate oxidase, NAD-dependent; putative tartrate dehydrogenase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.42 OHPLBJKB_03022 Sensor protein KdpD 0.73 OHPLBJKB_01933 D-malate dehydrogenase [decarboxylating] low > 73
Klebsiella michiganensis M5al 0.41 BWI76_RS08305 two-component sensor histidine kinase 0.74 BWI76_RS10680 tartrate dehydrogenase low > 92
Dickeya dianthicola 67-19 0.41 HGI48_RS06415 two-component system sensor histidine kinase KdpD 0.66 HGI48_RS04605 tartrate dehydrogenase low > 71
Variovorax sp. SCN45 0.41 GFF3520 Osmosensitive K+ channel histidine kinase KdpD 0.65 GFF6198 D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83) low > 127
Dickeya dianthicola ME23 0.41 DZA65_RS06760 two-component system sensor histidine kinase KdbD 0.66 DZA65_RS04525 tartrate dehydrogenase low > 75
Dickeya dadantii 3937 0.41 DDA3937_RS06370 two-component system sensor histidine kinase KdpD 0.67 DDA3937_RS04645 tartrate dehydrogenase low > 74
Variovorax sp. OAS795 0.40 ABID97_RS01010 DUF4118 domain-containing protein 0.75 ABID97_RS25885 tartrate dehydrogenase low > 91
Pantoea sp. MT58 0.40 IAI47_01250 two-component system sensor histidine kinase KdbD 0.66 IAI47_17525 tartrate dehydrogenase low > 76
Bosea sp. OAE506 0.32 ABIE41_RS24230 sensor histidine kinase KdpD 0.66 ABIE41_RS22540 tartrate dehydrogenase low > 77
Rhodopseudomonas palustris CGA009 0.32 TX73_015550 sensor histidine kinase KdpD 0.68 TX73_008960 tartrate dehydrogenase low > 86
Pseudomonas fluorescens FW300-N2E2 0.28 Pf6N2E2_2491 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.75 Pf6N2E2_369 Tartrate dehydrogenase (EC 1.1.1.93) @ Tartrate decarboxylase (EC 4.1.1.73) @ D-malic enzyme (EC 1.1.1.83) low > 103
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS13210 sensor histidine kinase KdpD 0.29 ABZR86_RS00740 isocitrate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.27 Xcc-8004.4379.1 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.30 Xcc-8004.4057.1 Isocitrate dehydrogenase [NAD] (EC 1.1.1.41) — —
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_03300 histidine kinase 0.75 AO356_26735 tartrate dehydrogenase low > 104
Pseudomonas syringae pv. syringae B728a ΔmexB 0.27 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.71 Psyr_2396 Tartrate dehydrogenase low > 86
Pseudomonas fluorescens SBW25 0.27 PFLU_RS08240 sensor histidine kinase KdpD 0.73 PFLU_RS19735 tartrate dehydrogenase low > 109
Pseudomonas syringae pv. syringae B728a 0.27 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.71 Psyr_2396 Tartrate dehydrogenase low > 86
Pseudomonas fluorescens SBW25-INTG 0.27 PFLU_RS08240 sensor histidine kinase KdpD 0.73 PFLU_RS19735 tartrate dehydrogenase low > 109
Pseudomonas fluorescens FW300-N1B4 0.26 Pf1N1B4_312 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.75 Pf1N1B4_4932 Tartrate dehydrogenase (EC 1.1.1.93) / Tartrate decarboxylase (EC 4.1.1.73) / D-malic enzyme (EC 1.1.1.83) low > 87
Hydrogenophaga sp. GW460-11-11-14-LB1 0.26 GFF4474 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.65 GFF3852 Tartrate dehydrogenase (EC 1.1.1.93) / Tartrate decarboxylase (EC 4.1.1.73) / D-malic enzyme (EC 1.1.1.83) low > 90
Mycobacterium tuberculosis H37Rv 0.20 Rv1028c Probable sensor protein KdpD 0.33 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) — —

Not shown: 26 genomes with orthologs for QEN71_RS24345 only; 13 genomes with orthologs for QEN71_RS32005 only