Conservation of cofitness between PP_2328 and PP_3999 in Pseudomonas putida KT2440

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2328 Phosphoadenosine phosphosulfate reductase 1.0 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase 0.78 1
Pseudomonas simiae WCS417 0.92 PS417_21125 phosphoadenosine phosphosulfate reductase 0.83 PS417_16465 sirohydrochlorin ferrochelatase low > 88
Pseudomonas fluorescens SBW25 0.92 PFLU_RS22740 phosphoadenylyl-sulfate reductase 0.84 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.47 32
Pseudomonas fluorescens SBW25-INTG 0.92 PFLU_RS22740 phosphoadenylyl-sulfate reductase 0.84 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.69 1
Pseudomonas sp. RS175 0.91 PFR28_02935 Phosphoadenosine phosphosulfate reductase 0.84 PFR28_02603 Siroheme synthase — —
Pseudomonas fluorescens FW300-N2E3 0.91 AO353_00935 phosphoadenosine phosphosulfate reductase 0.84 AO353_27625 sirohydrochlorin ferrochelatase — —
Pseudomonas syringae pv. syringae B728a 0.91 Psyr_2078 phosphoadenylylsulfate reductase (thioredoxin) 0.82 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.91 Psyr_2078 phosphoadenylylsulfate reductase (thioredoxin) 0.82 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.91 Pf6N2E2_6054 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) 0.84 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) — —
Pseudomonas fluorescens FW300-N2C3 0.90 AO356_20830 phosphoadenosine phosphosulfate reductase 0.84 AO356_22200 sirohydrochlorin ferrochelatase 0.62 28
Pseudomonas fluorescens GW456-L13 0.90 PfGW456L13_4125 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) 0.84 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.75 20
Pseudomonas fluorescens FW300-N1B4 0.90 Pf1N1B4_3812 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) 0.83 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.70 19
Pseudomonas stutzeri RCH2 0.85 Psest_2328 phosophoadenylyl-sulfate reductase (thioredoxin)/thioredoxin-dependent adenylylsulfate APS reductase 0.77 Psest_2037 uroporphyrin-III C-methyltransferase — —
Acinetobacter radioresistens SK82 0.66 MPMX26_00649 Phosphoadenosine phosphosulfate reductase 0.55 MPMX26_00706 Siroheme synthase — —
Castellaniella sp019104865 MT123 0.40 ABCV34_RS14110 phosphoadenylyl-sulfate reductase 0.37 ABCV34_RS00210 siroheme synthase CysG low > 48
Bosea sp. OAE506 0.32 ABIE41_RS15375 phosphoadenylyl-sulfate reductase 0.30 ABIE41_RS15910 siroheme synthase CysG — —
Rhizobium sp. OAE497 0.31 ABIE40_RS04475 phosphoadenylyl-sulfate reductase 0.33 ABIE40_RS09140 siroheme synthase CysG 0.93 3
Agrobacterium fabrum C58 0.31 Atu0818 phosphoadenosine phosphosulfate reductase 0.33 Atu1454 siroheme synthase 0.60 3
Mycobacterium tuberculosis H37Rv 0.21 Rv2392 Probable 3'-phosphoadenosine 5'-phosphosulfate reductase CysH (PAPS reductase, thioredoxin DEP.) (padops reductase) (3'-phosphoadenylylsulfate reductase) (PAPS sulfotransferase) 0.20 Rv2847c Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase — —
Lysobacter sp. OAE881 0.21 ABIE51_RS15835 phosphoadenylyl-sulfate reductase 0.40 ABIE51_RS15855 siroheme synthase CysG 0.97 16
Dinoroseobacter shibae DFL-12 0.21 Dshi_1152 phosphoadenosine phosphosulfate reductase (RefSeq) 0.28 Dshi_1671 uroporphyrin-III C-methyltransferase (RefSeq) — —
Rhodopseudomonas palustris CGA009 0.20 TX73_003880 phosphoadenylyl-sulfate reductase 0.35 TX73_021850 siroheme synthase CysG 0.71 5
Pantoea sp. MT58 0.19 IAI47_04160 phosphoadenylyl-sulfate reductase 0.47 IAI47_04175 uroporphyrinogen-III C-methyltransferase 0.90 33
Dyella japonica UNC79MFTsu3.2 0.19 ABZR86_RS05895 phosphoadenylyl-sulfate reductase 0.42 ABZR86_RS05880 siroheme synthase CysG 0.90 55
Rhodanobacter denitrificans FW104-10B01 0.19 LRK54_RS00920 phosphoadenylyl-sulfate reductase 0.37 LRK54_RS00910 siroheme synthase CysG 0.64 2
Rhodanobacter denitrificans MT42 0.19 LRK55_RS00695 phosphoadenylyl-sulfate reductase 0.36 LRK55_RS00685 siroheme synthase CysG low > 63
Dickeya dadantii 3937 0.18 DDA3937_RS16935 phosphoadenylyl-sulfate reductase 0.46 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase 0.73 17
Serratia liquefaciens MT49 0.18 IAI46_03695 phosphoadenylyl-sulfate reductase 0.48 IAI46_23670 uroporphyrinogen-III C-methyltransferase low > 86
Pectobacterium carotovorum WPP14 0.18 HER17_RS04245 phosphoadenylyl-sulfate reductase 0.48 HER17_RS01835 siroheme synthase CysG low > 75
Dickeya dianthicola 67-19 0.18 HGI48_RS17005 phosphoadenylyl-sulfate reductase 0.46 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase low > 71
Dickeya dianthicola ME23 0.18 DZA65_RS18080 phosphoadenylyl-sulfate reductase 0.45 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase low > 75
Rhodanobacter sp. FW510-T8 0.18 OKGIIK_05970 cysH phosphoadenylyl-sulfate reductase 0.38 OKGIIK_05980 cysG siroheme synthase CysG low > 52
Enterobacter sp. TBS_079 0.17 MPMX20_03641 Phosphoadenosine phosphosulfate reductase 0.50 MPMX20_04271 Siroheme synthase low > 85
Erwinia tracheiphila SCR3 0.17 LU632_RS06410 phosphoadenylyl-sulfate reductase 0.49 LU632_RS06420 cysG siroheme synthase CysG 0.60 52
Rhodospirillum rubrum S1H 0.17 Rru_A1929 Phosphoadenosine phosphosulfate reductase (NCBI) 0.30 Rru_A1933 Uroporphyrin-III C-methyltransferase (NCBI) — —
Klebsiella michiganensis M5al 0.17 BWI76_RS22755 phosphoadenosine phosphosulfate reductase 0.48 BWI76_RS26055 siroheme synthase 0.82 4
Rahnella sp. WP5 0.17 EX31_RS07895 phosphoadenylyl-sulfate reductase 0.47 EX31_RS04680 uroporphyrinogen-III C-methyltransferase low > 89
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.17 GFF4818 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) 0.48 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) — —
Enterobacter asburiae PDN3 0.17 EX28DRAFT_2851 phosphoadenosine phosphosulfate reductase, thioredoxin dependent 0.50 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase 0.52 72
Escherichia coli ECRC62 0.17 BNILDI_10745 cysH phosphoadenosine phosphosulfate reductase 0.49 BNILDI_02540 cysG siroheme synthase CysG — —
Escherichia coli ECOR38 0.17 HEPCGN_19085 cysH phosphoadenosine phosphosulfate reductase 0.48 HEPCGN_16010 cysG siroheme synthase CysG low > 85
Escherichia coli ECOR27 0.17 NOLOHH_12195 cysH phosphoadenosine phosphosulfate reductase 0.49 NOLOHH_08980 cysG siroheme synthase CysG low > 57
Escherichia coli BL21 0.17 ECD_02607 phosphoadenosine phosphosulfate reductase; PAPS reductase, thioredoxin dependent 0.49 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.17 OHPLBJKB_00971 Phosphoadenosine phosphosulfate reductase 0.49 OHPLBJKB_00334 Siroheme synthase low > 73
Escherichia coli ECRC101 0.17 MCAODC_10905 cysH phosphoadenosine phosphosulfate reductase 0.48 MCAODC_07710 cysG siroheme synthase CysG — —
Escherichia coli ECRC98 0.17 JDDGAC_24045 cysH phosphoadenosine phosphosulfate reductase 0.48 JDDGAC_20810 cysG siroheme synthase CysG — —
Escherichia coli BW25113 0.17 b2762 cysH phosphoadenosine phosphosulfate reductase (NCBI) 0.49 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) 0.94 7
Escherichia coli ECRC101 0.17 OKFHMN_20380 cysH phosphoadenosine phosphosulfate reductase 0.48 OKFHMN_17180 cysG siroheme synthase CysG — —
Escherichia coli ECRC102 0.17 NIAGMN_18150 cysH phosphoadenosine phosphosulfate reductase 0.48 NIAGMN_14950 cysG siroheme synthase CysG — —
Escherichia coli ECRC99 0.17 KEDOAH_07745 cysH phosphoadenosine phosphosulfate reductase 0.48 KEDOAH_10960 cysG siroheme synthase CysG — —
Escherichia coli Nissle 1917 0.17 ECOLIN_RS15400 phosphoadenosine phosphosulfate reductase 0.48 ECOLIN_RS19285 siroheme synthase CysG low > 52
Alteromonas macleodii MIT1002 0.17 MIT1002_03378 Phosphoadenosine phosphosulfate reductase 0.52 MIT1002_00665 Siroheme synthase — —
Escherichia fergusonii Becca 0.16 EFB2_01155 Phosphoadenosine phosphosulfate reductase 0.48 EFB2_00454 Siroheme synthase low > 86
Kangiella aquimarina DSM 16071 0.16 B158DRAFT_2162 phosphoadenosine phosphosulfate reductase, thioredoxin dependent 0.43 B158DRAFT_2163 uroporphyrin-III C-methyltransferase low > 40

Not shown: 20 genomes with orthologs for PP_2328 only; 3 genomes with orthologs for PP_3999 only