Conservation of cofitness between OKFHMN_10730 and OKFHMN_24520 in Escherichia coli ECRC100

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 1.0 OKFHMN_24520 hisG ATP phosphoribosyltransferase 0.96 9
Escherichia coli ECRC99 1.00 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 1.00 KEDOAH_03630 hisG ATP phosphoribosyltransferase — —
Escherichia coli ECRC102 1.00 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 1.00 NIAGMN_22465 hisG ATP phosphoribosyltransferase — —
Escherichia coli ECRC98 1.00 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 1.00 JDDGAC_28630 hisG ATP phosphoribosyltransferase 0.92 17
Escherichia coli ECRC101 1.00 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 1.00 MCAODC_20420 hisG ATP phosphoribosyltransferase 0.86 46
Escherichia coli BL21 0.99 ECD_00073 3-isopropylmalate dehydratase small subunit 0.99 ECD_01921 ATP phosphoribosyltransferase low > 61
Escherichia coli ECOR27 0.99 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 1.00 NOLOHH_15835 hisG ATP phosphoribosyltransferase low > 75
Escherichia coli ECRC62 0.99 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 1.00 BNILDI_14745 hisG ATP phosphoribosyltransferase 0.85 69
Escherichia coli BW25113 0.99 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 1.00 b2019 hisG ATP phosphoribosyltransferase (NCBI) 0.94 16
Escherichia coli Nissle 1917 0.99 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 1.00 ECOLIN_RS11940 ATP phosphoribosyltransferase — —
Escherichia fergusonii Becca 0.99 EFB2_03974 3-isopropylmalate dehydratase small subunit 1.00 EFB2_01837 ATP phosphoribosyltransferase low > 86
Escherichia coli ECOR38 0.99 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.99 HEPCGN_03225 hisG ATP phosphoribosyltransferase 0.86 56
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 1.00 OHPLBJKB_01681 ATP phosphoribosyltransferase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.96 GFF3913 ATP phosphoribosyltransferase (EC 2.4.2.17) low > 78
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.96 EX28DRAFT_0540 ATP phosphoribosyltransferase 0.81 16
Enterobacter sp. TBS_079 0.89 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.96 MPMX20_03001 ATP phosphoribosyltransferase 0.93 6
Klebsiella michiganensis M5al 0.87 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.94 BWI76_RS18920 ATP phosphoribosyltransferase 0.89 33
Dickeya dadantii 3937 0.83 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.90 DDA3937_RS09740 ATP phosphoribosyltransferase 0.65 60
Rahnella sp. WP5 0.83 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.90 EX31_RS11435 ATP phosphoribosyltransferase 0.86 72
Dickeya dianthicola ME23 0.82 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.90 DZA65_RS10060 ATP phosphoribosyltransferase low > 75
Dickeya dianthicola 67-19 0.82 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.90 HGI48_RS09750 ATP phosphoribosyltransferase low > 71
Pectobacterium carotovorum WPP14 0.80 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.90 HER17_RS12225 ATP phosphoribosyltransferase 0.93 48
Serratia liquefaciens MT49 0.80 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.89 IAI46_08215 ATP phosphoribosyltransferase low > 86
Pantoea sp. MT58 0.79 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.88 IAI47_07095 ATP phosphoribosyltransferase 0.96 15
Erwinia tracheiphila SCR3 0.72 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.89 LU632_RS08950 hisG ATP phosphoribosyltransferase 0.67 46
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_12610 3-isopropylmalate dehydratase small subunit 0.68 CSW01_05745 ATP phosphoribosyltransferase low > 62
Shewanella loihica PV-4 0.61 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.69 Shew_2197 hisG ATP phosphoribosyltransferase (RefSeq) 0.97 18
Xanthomonas campestris pv. campestris strain 8004 0.60 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.36 Xcc-8004.2949.1 ATP phosphoribosyltransferase (EC 2.4.2.17) 0.68 59
Alteromonas macleodii MIT1002 0.59 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.66 MIT1002_02632 ATP phosphoribosyltransferase 0.85 54
Shewanella sp. ANA-3 0.58 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.69 Shewana3_1854 hisG ATP phosphoribosyltransferase (RefSeq) 0.86 72
Shewanella oneidensis MR-1 0.58 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.69 SO2074 hisG ATP phosphoribosyltransferase (NCBI ptt file) 0.97 13
Shewanella amazonensis SB2B 0.58 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.67 Sama_1941 hisG ATP phosphoribosyltransferase (RefSeq) 0.92 39
Kangiella aquimarina DSM 16071 0.57 B158DRAFT_1320 3-isopropylmalate dehydratase, small subunit 0.14 B158DRAFT_2287 ATP phosphoribosyltransferase low > 40
Bosea sp. OAE506 0.45 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit 0.12 ABIE41_RS22120 ATP phosphoribosyltransferase — —
Rhodanobacter denitrificans MT42 0.45 LRK55_RS07100 3-isopropylmalate dehydratase small subunit 0.39 LRK55_RS01390 ATP phosphoribosyltransferase low > 63
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS07370 3-isopropylmalate dehydratase small subunit 0.39 LRK54_RS01610 ATP phosphoribosyltransferase low > 59
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09440 3-isopropylmalate dehydratase small subunit 0.45 CA264_05025 ATP phosphoribosyltransferase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.42 CA265_RS15840 3-isopropylmalate dehydratase small subunit 0.37 CA265_RS03640 ATP phosphoribosyltransferase 0.90 32
Mucilaginibacter yixingensis YX-36 DSM 26809 0.42 ABZR88_RS11600 3-isopropylmalate dehydratase small subunit 0.41 ABZR88_RS06885 ATP phosphoribosyltransferase — —
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14140 3-isopropylmalate dehydratase small subunit 0.43 HMPREF1181_RS04865 ATP phosphoribosyltransferase 0.80 42
Bifidobacterium breve UCC2003 0.41 BBR_RS19625 3-isopropylmalate dehydratase small subunit 0.21 BBR_RS15790 ATP phosphoribosyltransferase low > 34
Phocaeicola dorei CL03T12C01 0.40 ABI39_RS10205 3-isopropylmalate dehydratase small subunit 0.42 ABI39_RS11830 ATP phosphoribosyltransferase 0.67 60
Phocaeicola vulgatus CL09T03C04 0.40 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit 0.42 HMPREF1058_RS15870 ATP phosphoribosyltransferase 0.79 19
Parabacteroides merdae CL09T00C40 0.39 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit 0.41 HMPREF1078_RS02455 ATP phosphoribosyltransferase 0.87 23
Dyella japonica UNC79MFTsu3.2 0.39 ABZR86_RS15955 3-isopropylmalate dehydratase small subunit 0.40 ABZR86_RS06735 ATP phosphoribosyltransferase 0.87 65
Lysobacter sp. OAE881 0.39 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit 0.42 ABIE51_RS13330 ATP phosphoribosyltransferase 0.87 38
Bacteroides ovatus ATCC 8483 0.38 BACOVA_04602 3-isopropylmalate dehydratase, small subunit 0.38 BACOVA_01235 ATP phosphoribosyltransferase 0.93 21
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_2060 3-isopropylmalate dehydratase, small subunit 0.44 Echvi_2460 ATP phosphoribosyltransferase — —
Mycobacterium tuberculosis H37Rv 0.37 Rv2987c Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.20 Rv2121c ATP phosphoribosyltransferase HisG — —
Bacteroides thetaiotaomicron VPI-5482 0.37 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) 0.42 BT0200 ATP phosphoribosyltransferase (NCBI ptt file) 0.82 26
Brevundimonas sp. GW460-12-10-14-LB2 0.37 A4249_RS10000 3-isopropylmalate dehydratase small subunit 0.50 A4249_RS10690 ATP phosphoribosyltransferase 0.99 19

Not shown: 47 genomes with orthologs for OKFHMN_10730 only; 5 genomes with orthologs for OKFHMN_24520 only