Conservation of cofitness between BWI76_RS20390 and BWI76_RS08580 in Klebsiella michiganensis M5al

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 1.0 BWI76_RS08580 quinolinate synthetase 0.68 1
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.92 GFF4 Quinolinate synthetase (EC 2.5.1.72) — —
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.93 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) 0.84 5
Enterobacter sp. TBS_079 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.94 MPMX20_01377 Quinolinate synthase A low > 85
Escherichia coli BL21 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.90 ECD_00703 quinolinate synthase, subunit A low > 61
Escherichia fergusonii Becca 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.90 EFB2_03356 Quinolinate synthase A low > 86
Escherichia coli BW25113 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.90 b0750 nadA quinolinate synthetase (NCBI) 0.75 5
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.90 OHPLBJKB_02963 Quinolinate synthase A low > 73
Escherichia coli Nissle 1917 0.83 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.90 ECOLIN_RS03990 quinolinate synthase NadA 0.56 33
Escherichia coli ECOR27 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 NOLOHH_23190 nadA quinolinate synthase NadA 0.75 37
Escherichia coli ECRC62 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 BNILDI_21185 nadA quinolinate synthase NadA 0.85 33
Escherichia coli ECRC99 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 KEDOAH_21205 nadA quinolinate synthase NadA — —
Escherichia coli ECRC101 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 MCAODC_25980 nadA quinolinate synthase NadA 0.93 6
Escherichia coli ECRC102 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 NIAGMN_04810 nadA quinolinate synthase NadA — —
Escherichia coli ECRC98 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 JDDGAC_10415 nadA quinolinate synthase NadA low > 86
Escherichia coli ECRC100 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 OKFHMN_06760 nadA quinolinate synthase NadA 0.84 23
Escherichia coli ECOR38 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.90 HEPCGN_01515 nadA quinolinate synthase NadA 0.92 17
Dickeya dadantii 3937 0.75 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB 0.81 DDA3937_RS06545 quinolinate synthase NadA low > 74
Dickeya dianthicola ME23 0.74 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB 0.82 DZA65_RS06945 quinolinate synthase NadA 0.44 47
Pantoea sp. MT58 0.73 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.88 IAI47_13635 quinolinate synthase NadA 0.72 47
Serratia liquefaciens MT49 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.87 IAI46_06380 quinolinate synthase NadA low > 86
Rahnella sp. WP5 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.85 EX31_RS23525 quinolinate synthase NadA low > 89
Dickeya dianthicola 67-19 0.70 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB 0.82 HGI48_RS06595 quinolinate synthase NadA low > 71
Pectobacterium carotovorum WPP14 0.70 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB 0.87 HER17_RS14820 quinolinate synthase NadA low > 75
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_10525 DUF3410 domain-containing protein 0.75 CSW01_09180 quinolinate synthase — —
Shewanella sp. ANA-3 0.43 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.73 Shewana3_2128 quinolinate synthetase (RefSeq) — —
Shewanella oneidensis MR-1 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.74 SO2342 nadA quinolinate synthetase complex, subunit A (NCBI ptt file) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.63 Psyr_1542 quinolinate synthetase — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.63 Psyr_1542 quinolinate synthetase — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.65 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) — —
Shewanella amazonensis SB2B 0.42 Sama_2153 erythronate-4-phosphate dehydrogenase (RefSeq) 0.73 Sama_1712 quinolinate synthetase (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_00545 erythronate-4-phosphate dehydrogenase 0.64 AO353_03525 quinolinate synthase A — —
Shewanella loihica PV-4 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.75 Shew_1928 quinolinate synthetase (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.65 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas simiae WCS417 0.41 PS417_07535 erythronate-4-phosphate dehydrogenase 0.64 PS417_22385 quinolinate synthase A — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_02365 erythronate-4-phosphate dehydrogenase 0.65 AO356_18145 quinolinate synthase A — —
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.65 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas fluorescens SBW25 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.64 PFLU_RS24025 quinolinate synthase NadA — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.64 PFLU_RS24025 quinolinate synthase NadA — —
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_1308 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) 0.69 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas sp. RS175 0.39 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.64 PFR28_03388 Quinolinate synthase A — —
Marinobacter adhaerens HP15 0.38 HP15_2098 erythronate-4-phosphate dehydrogenase 0.68 HP15_2032 quinolinate synthetase complex, A subunit — —
Pseudomonas putida KT2440 0.38 PP_2117 Erythronate-4-phosphate dehydrogenase 0.66 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit — —
Pseudomonas sp. S08-1 0.37 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.66 OH686_19190 quinolinate synthetase complex, A subunit — —
Pseudomonas stutzeri RCH2 0.37 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.66 Psest_1509 quinolinate synthetase complex, A subunit — —
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS02440 4-phosphoerythronate dehydrogenase PdxB 0.34 HMPREF1181_RS01920 quinolinate synthase NadA — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS10820 4-phosphoerythronate dehydrogenase PdxB 0.35 HMPREF1058_RS11230 quinolinate synthase NadA — —
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS06250 4-phosphoerythronate dehydrogenase PdxB 0.35 ABI39_RS05755 quinolinate synthase NadA — —
Bacteroides ovatus ATCC 8483 0.33 BACOVA_01953 4-phosphoerythronate dehydrogenase 0.34 BACOVA_02839 quinolinate synthetase complex, A subunit 0.78 33
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS19150 4-phosphoerythronate dehydrogenase PdxB 0.34 HMPREF1078_RS06555 quinolinate synthase NadA — —
Bacteroides thetaiotaomicron VPI-5482 0.32 BT3361 erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.34 BT3164 quinolinate synthetase A (NCBI ptt file) 0.86 14
Alteromonas macleodii MIT1002 0.32 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.72 MIT1002_01344 Quinolinate synthase A — —
Acinetobacter radioresistens SK82 0.31 MPMX26_02238 Erythronate-4-phosphate dehydrogenase 0.69 MPMX26_02602 Quinolinate synthase A low > 36

Not shown: 1 genomes with orthologs for BWI76_RS20390 only; 41 genomes with orthologs for BWI76_RS08580 only