Conservation of cofitness between BWI76_RS20390 and BWI76_RS01555 in Klebsiella michiganensis M5al

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 1.0 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.56 7
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.93 GFF4198 Thiamin biosynthesis protein ThiC low > 78
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.95 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.69 31
Enterobacter sp. TBS_079 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.94 MPMX20_00217 Phosphomethylpyrimidine synthase 0.56 7
Escherichia coli BL21 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.93 ECD_03871 phosphomethylpyrimidine synthase low > 61
Escherichia fergusonii Becca 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.93 EFB2_04617 Phosphomethylpyrimidine synthase low > 86
Escherichia coli BW25113 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.93 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.74 6
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.93 OHPLBJKB_04056 Phosphomethylpyrimidine synthase low > 73
Escherichia coli Nissle 1917 0.83 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.93 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.69 19
Escherichia coli ECOR27 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC low > 75
Escherichia coli ECRC62 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.86 32
Escherichia coli ECRC100 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.84 24
Escherichia coli ECRC101 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.94 4
Escherichia coli ECRC99 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC102 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC — —
Escherichia coli ECRC98 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC low > 86
Escherichia coli ECOR38 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.93 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.94 11
Dickeya dadantii 3937 0.75 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB 0.85 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC low > 74
Dickeya dianthicola ME23 0.74 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB 0.85 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.52 16
Pantoea sp. MT58 0.73 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.83 IAI47_18085 phosphomethylpyrimidine synthase ThiC low > 76
Erwinia tracheiphila SCR3 0.73 LU632_RS07815 DUF3410 domain-containing protein 0.82 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC — —
Serratia liquefaciens MT49 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.85 IAI46_01320 phosphomethylpyrimidine synthase ThiC low > 86
Rahnella sp. WP5 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.86 EX31_RS16815 phosphomethylpyrimidine synthase ThiC low > 89
Dickeya dianthicola 67-19 0.70 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB 0.84 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC low > 71
Pectobacterium carotovorum WPP14 0.70 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB 0.86 HER17_RS20380 phosphomethylpyrimidine synthase ThiC low > 75
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_10525 DUF3410 domain-containing protein 0.74 CSW01_00335 phosphomethylpyrimidine synthase — —
Shewanella sp. ANA-3 0.43 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.74 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) — —
Shewanella oneidensis MR-1 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.74 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.70 Psyr_0544 hydroxymethylpyrimidine synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.70 Psyr_0544 hydroxymethylpyrimidine synthase — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.70 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Shewanella amazonensis SB2B 0.42 Sama_2153 erythronate-4-phosphate dehydrogenase (RefSeq) 0.76 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_00545 erythronate-4-phosphate dehydrogenase 0.70 AO353_13010 thiamine biosynthesis protein ThiC — —
Shewanella loihica PV-4 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.77 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.70 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Pseudomonas simiae WCS417 0.41 PS417_07535 erythronate-4-phosphate dehydrogenase 0.70 PS417_02355 thiamine biosynthesis protein ThiC — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_02365 erythronate-4-phosphate dehydrogenase 0.70 AO356_08810 thiamine biosynthesis protein ThiC — —
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.70 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.70 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC — —
Pseudomonas fluorescens SBW25 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.70 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC — —
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_1308 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase — —
Pseudomonas sp. RS175 0.39 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.71 PFR28_05091 Phosphomethylpyrimidine synthase — —
Marinobacter adhaerens HP15 0.38 HP15_2098 erythronate-4-phosphate dehydrogenase 0.69 HP15_453 thiamine biosynthesis protein thiC — —
Pseudomonas putida KT2440 0.38 PP_2117 Erythronate-4-phosphate dehydrogenase 0.71 PP_4922 Phosphomethylpyrimidine synthase — —
Pseudomonas sp. S08-1 0.37 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.71 OH686_15885 phosphomethylpyrimidine synthase — —
Pseudomonas stutzeri RCH2 0.37 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.70 Psest_0477 thiamine biosynthesis protein ThiC — —
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS02440 4-phosphoerythronate dehydrogenase PdxB 0.55 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS10820 4-phosphoerythronate dehydrogenase PdxB 0.55 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.89 8
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS06250 4-phosphoerythronate dehydrogenase PdxB 0.56 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.76 22
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS19150 4-phosphoerythronate dehydrogenase PdxB 0.57 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC low > 61
Bacteroides ovatus ATCC 8483 0.33 BACOVA_01953 4-phosphoerythronate dehydrogenase 0.55 BACOVA_02358 thiamine biosynthesis protein ThiC 0.66 85
Bacteroides thetaiotaomicron VPI-5482 0.32 BT3361 erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.56 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) low > 81
Alteromonas macleodii MIT1002 0.32 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.75 MIT1002_00097 Phosphomethylpyrimidine synthase — —
Acinetobacter radioresistens SK82 0.31 MPMX26_02238 Erythronate-4-phosphate dehydrogenase 0.68 MPMX26_00180 Phosphomethylpyrimidine synthase low > 36

Not shown: 0 genomes with orthologs for BWI76_RS20390 only; 40 genomes with orthologs for BWI76_RS01555 only