Conservation of cofitness between BBR_RS14535 and BBR_RS14075 in Bifidobacterium breve UCC2003

43 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS14535 pyridoxal phosphate-dependent aminotransferase 1.0 BBR_RS14075 glutamate-5-semialdehyde dehydrogenase 0.31 9
Phocaeicola dorei CL03T12C01 0.37 ABI39_RS19290 pyridoxal phosphate-dependent aminotransferase 0.38 ABI39_RS02875 glutamate-5-semialdehyde dehydrogenase low > 72
Bacteroides ovatus ATCC 8483 0.37 BACOVA_00803 aminotransferase, class I/II 0.39 BACOVA_03534 glutamate-5-semialdehyde dehydrogenase low > 94
Parabacteroides merdae CL09T00C40 0.37 HMPREF1078_RS03550 MalY/PatB family protein 0.38 HMPREF1078_RS10655 glutamate-5-semialdehyde dehydrogenase low > 61
Bacteroides thetaiotaomicron VPI-5482 0.36 BT1398 putative aminotransferase B (NCBI ptt file) 0.39 BT3718 gamma-glutamyl phosphate reductase (NCBI ptt file) low > 81
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS07560 pyridoxal phosphate-dependent aminotransferase 0.38 HMPREF1058_RS08645 glutamate-5-semialdehyde dehydrogenase low > 67
Bacteroides stercoris CC31F 0.33 HMPREF1181_RS06410 pyridoxal phosphate-dependent aminotransferase 0.40 HMPREF1181_RS03320 glutamate-5-semialdehyde dehydrogenase low > 56
Marinobacter adhaerens HP15 0.32 HP15_3572 aminotransferase, classes I and II 0.40 HP15_601 gamma-glutamyl phosphate reductase — —
Desulfovibrio vulgaris Miyazaki F 0.30 DvMF_1822 aminotransferase class I and II (RefSeq) 0.35 DvMF_0612 proA gamma-glutamyl phosphate reductase (RefSeq) low > 51
Serratia liquefaciens MT49 0.29 IAI46_19310 pyridoxal phosphate-dependent aminotransferase 0.42 IAI46_04435 glutamate-5-semialdehyde dehydrogenase 0.43 33
Dechlorosoma suillum PS 0.29 Dsui_3257 bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities 0.40 Dsui_1220 gamma-glutamyl phosphate reductase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.29 GFF2547 Aspartate aminotransferase (EC 2.6.1.1) 0.44 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 78
Pseudomonas fluorescens FW300-N2C3 0.29 AO356_26930 aminotransferase 0.38 AO356_15290 gamma-glutamyl phosphate reductase low > 104
Pseudomonas fluorescens FW300-N2E2 0.28 Pf6N2E2_1210 putative aminotransferase 0.37 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 103
Enterobacter sp. TBS_079 0.28 MPMX20_04048 Cystathionine beta-lyase PatB 0.43 MPMX20_00928 Gamma-glutamyl phosphate reductase low > 85
Escherichia coli Nissle 1917 0.27 ECOLIN_RS05400 PatB family C-S lyase 0.42 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase — —
Bosea sp. OAE506 0.27 ABIE41_RS12595 PatB family C-S lyase 0.31 ABIE41_RS07580 glutamate-5-semialdehyde dehydrogenase — —
Escherichia fergusonii Becca 0.27 EFB2_03048 Cystathionine beta-lyase PatB 0.41 EFB2_03777 Gamma-glutamyl phosphate reductase low > 86
Desulfovibrio vulgaris Hildenborough JW710 0.27 DVU0171 patB hemolysin-related protein (TIGR) 0.35 DVU1953 proA gamma-glutamyl phosphate reductase (TIGR) low > 55
Alteromonas macleodii MIT1002 0.26 MIT1002_03179 Cystathionine beta-lyase PatB 0.39 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.98 13
Pseudomonas simiae WCS417 0.26 PS417_12965 aminotransferase 0.38 PS417_24745 gamma-glutamyl phosphate reductase low > 88
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_3090 putative aminotransferase 0.36 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 87
Pseudomonas sp. RS175 0.26 PFR28_02099 Cystathionine beta-lyase PatB 0.38 PFR28_03872 Gamma-glutamyl phosphate reductase — —
Pantoea sp. MT58 0.26 IAI47_10360 pyridoxal phosphate-dependent aminotransferase 0.42 IAI47_15115 glutamate-5-semialdehyde dehydrogenase low > 76
Rahnella sp. WP5 0.25 EX31_RS06865 pyridoxal phosphate-dependent aminotransferase 0.42 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase low > 89
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_4946 putative aminotransferase 0.38 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) low > 87
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS13630 putative C-S lyase 0.38 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase — —
Escherichia coli ECOR38 0.25 HEPCGN_14250 pyridoxal phosphate-dependent aminotransferase 0.42 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase low > 85
Pseudomonas fluorescens SBW25 0.25 PFLU_RS13630 putative C-S lyase 0.38 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase — —
Escherichia coli ECRC99 0.25 KEDOAH_00520 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY 0.43 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase — —
Escherichia coli BL21 0.25 ECD_01591 PLP-dependent beta-cystathionase and maltose regulon regulator 0.43 ECD_00240 gamma-glutamylphosphate reductase low > 60
Escherichia coli ECRC98 0.25 JDDGAC_02175 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY 0.43 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase — —
Escherichia coli ECRC101 0.25 OKFHMN_27585 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY 0.43 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase — —
Dinoroseobacter shibae DFL-12 0.25 Dshi_0178 aminotransferase class I and II (RefSeq) 0.31 Dshi_1469 gamma-glutamyl phosphate reductase (RefSeq) — —
Escherichia coli ECRC101 0.25 MCAODC_17825 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY 0.43 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.25 RALBFv3_RS16055 putative C-S lyase 0.37 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase low > 76
Escherichia coli BW25113 0.25 b1622 malY bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon (NCBI) 0.42 b0243 proA gamma-glutamyl phosphate reductase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.25 OHPLBJKB_02104 Protein MalY 0.42 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase low > 73
Escherichia coli ECRC62 0.24 BNILDI_16890 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY 0.42 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase — —
Escherichia coli ECOR27 0.24 NOLOHH_18100 malY bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY 0.42 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.24 PGA1_c00860 cystathionine beta-lyase PatB 0.35 PGA1_c15520 gamma-glutamyl phosphate reductase ProA low > 62
Enterobacter asburiae PDN3 0.24 EX28DRAFT_1617 putative C-S lyase 0.43 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) low > 76
Klebsiella michiganensis M5al 0.24 BWI76_RS16300 bifunctional beta-cystathionase/maltose regulon regulatory protein 0.44 BWI76_RS05835 gamma-glutamyl-phosphate reductase low > 92
Mycobacterium tuberculosis H37Rv 0.20 Rv0075 Probable aminotransferase 0.42 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) low > 58

Not shown: 1 genomes with orthologs for BBR_RS14535 only; 57 genomes with orthologs for BBR_RS14075 only