| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b2029 | gnd | 6-phosphogluconate dehydrogenase (NCBI) | 1.0 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.53 | 16 |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS11990 | | NADP-dependent phosphogluconate dehydrogenase | 0.99 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | low | > 52 |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_15785 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | low | > 57 |
| Escherichia fergusonii Becca | 1.00 | EFB2_01826 | | 6-phosphogluconate dehydrogenase, decarboxylating | 0.99 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | low | > 86 |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_03680 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_24470 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_20470 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_28580 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_22415 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | — | — |
| Escherichia coli ECRC62 | 0.99 | BNILDI_14695 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | — | — |
| Escherichia coli BL21 | 0.99 | ECD_01931 | | 6-phosphogluconate dehydrogenase, decarboxylating | 1.00 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | low | > 60 |
| Escherichia coli ECOR38 | 0.99 | HEPCGN_03175 | gndA | NADP-dependent phosphogluconate dehydrogenase | 1.00 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | low | > 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.97 | GFF3903 | | 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) | 0.97 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | low | > 78 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.97 | OHPLBJKB_01659 | | 6-phosphogluconate dehydrogenase, decarboxylating | 1.00 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | low | > 73 |
| Enterobacter asburiae PDN3 | 0.96 | EX28DRAFT_0529 | | 6-phosphogluconate dehydrogenase (decarboxylating) | 0.94 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | low | > 76 |
| Enterobacter sp. TBS_079 | 0.96 | MPMX20_03014 | | 6-phosphogluconate dehydrogenase, decarboxylating | 0.95 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | low | > 85 |
| Klebsiella michiganensis M5al | 0.95 | BWI76_RS19025 | | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) | 0.95 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 0.41 | 55 |
| Serratia liquefaciens MT49 | 0.89 | IAI46_08160 | | NADP-dependent phosphogluconate dehydrogenase | 0.91 | IAI46_24530 | | methylenetetrahydrofolate reductase | — | — |
| Pantoea sp. MT58 | 0.89 | IAI47_07035 | | NADP-dependent phosphogluconate dehydrogenase | 0.92 | IAI47_00890 | | methylenetetrahydrofolate reductase | — | — |
| Dickeya dadantii 3937 | 0.89 | DDA3937_RS06805 | | NADP-dependent phosphogluconate dehydrogenase | 0.90 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.88 | HER17_RS14505 | | NADP-dependent phosphogluconate dehydrogenase | 0.88 | HER17_RS00950 | | methylenetetrahydrofolate reductase | low | > 75 |
| Rahnella sp. WP5 | 0.88 | EX31_RS11475 | | NADP-dependent phosphogluconate dehydrogenase | 0.89 | EX31_RS14205 | | methylenetetrahydrofolate reductase | — | — |
| Dickeya dianthicola ME23 | 0.88 | DZA65_RS07180 | | NADP-dependent phosphogluconate dehydrogenase | 0.88 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | low | > 75 |
| Dickeya dianthicola 67-19 | 0.87 | HGI48_RS06840 | | NADP-dependent phosphogluconate dehydrogenase | 0.88 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | low | > 71 |
| Erwinia tracheiphila SCR3 | 0.87 | LU632_RS08890 | gndA | NADP-dependent phosphogluconate dehydrogenase | 0.86 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | low | > 74 |
| Paraburkholderia sabiae LMG 24235 | 0.76 | QEN71_RS20525 | | NADP-dependent phosphogluconate dehydrogenase | 0.41 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.44 | 146 |
| Dyella japonica UNC79MFTsu3.2 | 0.75 | ABZR86_RS13330 | | NADP-dependent phosphogluconate dehydrogenase | 0.35 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 74 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.75 | H281DRAFT_03046 | | 6-phosphogluconate dehydrogenase (decarboxylating) | 0.40 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.74 | ABIE53_005122 | | 6-phosphogluconate dehydrogenase | 0.39 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | low | > 113 |
| Burkholderia phytofirmans PsJN | 0.73 | BPHYT_RS29625 | | 6-phosphogluconate dehydrogenase | 0.38 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | low | > 109 |
| Variovorax sp. SCN45 | 0.55 | GFF2954 | | 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) | 0.32 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | low | > 127 |
| Variovorax sp. OAS795 | 0.55 | ABID97_RS10190 | | decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase | 0.33 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 91 |
| Vibrio cholerae E7946 ATCC 55056 | 0.54 | CSW01_18635 | | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) | 0.79 | CSW01_13560 | | methylenetetrahydrofolate reductase | low | > 62 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.54 | Echvi_4222 | | 6-phosphogluconate dehydrogenase, decarboxylating | 0.21 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.37 | 41 |
| Bifidobacterium breve UCC2003 | 0.53 | BBR_RS11465 | | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) | 0.24 | BBR_RS15410 | | methylenetetrahydrofolate reductase [NAD(P)H] | — | — |
| Parabacteroides merdae CL09T00C40 | 0.52 | HMPREF1078_RS08640 | | decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase | 0.21 | HMPREF1078_RS07860 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 61 |
| Bacteroides stercoris CC31F | 0.48 | HMPREF1181_RS12525 | | decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase | 0.17 | HMPREF1181_RS00120 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 56 |
| Phocaeicola dorei CL03T12C01 | 0.48 | ABI39_RS14350 | | decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase | 0.19 | ABI39_RS15570 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 72 |
| Bacteroides ovatus ATCC 8483 | 0.48 | BACOVA_00509 | | phosphogluconate dehydrogenase (decarboxylating) | 0.15 | BACOVA_03666 | | methylenetetrahydrofolate reductase (NAD(P)H) | low | > 94 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.47 | BT1222 | | 6-phosphogluconate dehydrogenase,decarboxylating (NCBI ptt file) | 0.18 | BT3821 | | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.39 | 34 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.47 | ABZR88_RS02970 | | NADP-dependent phosphogluconate dehydrogenase | 0.22 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | — | — |
| Phocaeicola vulgatus CL09T03C04 | 0.47 | HMPREF1058_RS18025 | | decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase | 0.18 | HMPREF1058_RS01490 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 67 |
| Sinorhizobium meliloti 1021 | 0.47 | SMc04262 | | 6-phosphogluconate dehydrogenase | 0.36 | SMc01843 | | 5,10-methylenetetrahydrofolate reductase | low | > 103 |
| Rhizobium sp. OAE497 | 0.46 | ABIE40_RS11035 | | NADP-dependent phosphogluconate dehydrogenase | 0.41 | ABIE40_RS11950 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 107 |
| Alteromonas macleodii MIT1002 | 0.46 | MIT1002_02397 | | 6-phosphogluconate dehydrogenase, NADP(+)-dependent, decarboxylating | 0.70 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | low | > 70 |
| Agrobacterium fabrum C58 | 0.46 | Atu1526 | | 6-phosphogluconate dehydrogenase, decarboxylating | 0.38 | Atu2123 | | methylenetetrahydrofolate reductase | low | > 89 |
| Azospirillum brasilense Sp245 | 0.43 | AZOBR_RS15725 | | 6-phosphogluconate dehydrogenase | 0.54 | AZOBR_RS24245 | | 5 10-methylenetetrahydrofolate reductase | low | > 97 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.43 | CA265_RS09805 | | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) | 0.21 | CA265_RS23445 | | methylenetetrahydrofolate reductase [NAD(P)H] | low | > 88 |
| Shewanella amazonensis SB2B | 0.43 | Sama_1365 | | 6-phosphogluconate dehydrogenase (RefSeq) | 0.75 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | low | > 62 |
| Shewanella sp. ANA-3 | 0.43 | Shewana3_1677 | | 6-phosphogluconate dehydrogenase (RefSeq) | 0.75 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.43 | SO1902 | gnd | 6-phosphogluconate dehydrogenase, decarboxylating (NCBI ptt file) | 0.75 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.43 | Shew_2561 | | 6-phosphogluconate dehydrogenase (RefSeq) | 0.76 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | low | > 60 |
Not shown: 2 genomes with orthologs for b2029 only; 48 genomes with orthologs for b3941 only