Conservation of cofitness between b2752 and b3368 in Escherichia coli BW25113

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2752 cysD sulfate adenylyltransferase subunit 2 (NCBI) 1.0 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) 0.93 2
Escherichia coli ECOR38 1.00 HEPCGN_19620 cysD sulfate adenylyltransferase subunit CysD 1.00 HEPCGN_16010 cysG siroheme synthase CysG low > 85
Escherichia coli BL21 1.00 ECD_02602 sulfate adenylyltransferase, subunit 2 1.00 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase low > 60
Escherichia coli ECRC101 1.00 OKFHMN_20440 cysD sulfate adenylyltransferase subunit CysD 1.00 OKFHMN_17180 cysG siroheme synthase CysG — —
Escherichia coli ECRC99 1.00 KEDOAH_07700 cysD sulfate adenylyltransferase subunit CysD 1.00 KEDOAH_10960 cysG siroheme synthase CysG — —
Escherichia coli ECRC102 1.00 NIAGMN_18210 cysD sulfate adenylyltransferase subunit CysD 1.00 NIAGMN_14950 cysG siroheme synthase CysG — —
Escherichia coli ECRC101 1.00 MCAODC_10965 cysD sulfate adenylyltransferase subunit CysD 1.00 MCAODC_07710 cysG siroheme synthase CysG — —
Escherichia coli ECRC98 1.00 JDDGAC_24105 cysD sulfate adenylyltransferase subunit CysD 1.00 JDDGAC_20810 cysG siroheme synthase CysG — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00981 Sulfate adenylyltransferase subunit 2 1.00 OHPLBJKB_00334 Siroheme synthase low > 73
Escherichia coli ECOR27 1.00 NOLOHH_12255 cysD sulfate adenylyltransferase subunit CysD 1.00 NOLOHH_08980 cysG siroheme synthase CysG low > 57
Escherichia fergusonii Becca 1.00 EFB2_01158 Sulfate adenylyltransferase subunit 2 1.00 EFB2_00454 Siroheme synthase low > 86
Escherichia coli ECRC62 1.00 BNILDI_10805 cysD sulfate adenylyltransferase subunit CysD 1.00 BNILDI_02540 cysG siroheme synthase CysG — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS15385 sulfate adenylyltransferase subunit CysD 1.00 ECOLIN_RS19285 siroheme synthase CysG low > 52
Enterobacter sp. TBS_079 0.98 MPMX20_03638 Sulfate adenylyltransferase subunit 2 0.89 MPMX20_04271 Siroheme synthase low > 85
Klebsiella michiganensis M5al 0.97 BWI76_RS22700 sulfate adenylyltransferase subunit 2 0.88 BWI76_RS26055 siroheme synthase 0.65 5
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF4800 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) 0.92 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) low > 78
Enterobacter asburiae PDN3 0.97 EX28DRAFT_2848 sulfate adenylyltransferase, small subunit 0.89 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase 0.60 70
Dickeya dadantii 3937 0.95 DDA3937_RS16925 sulfate adenylyltransferase subunit CysD 0.51 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase 0.95 2
Dickeya dianthicola 67-19 0.95 HGI48_RS16995 sulfate adenylyltransferase subunit CysD 0.51 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase 0.72 53
Dickeya dianthicola ME23 0.95 DZA65_RS18070 sulfate adenylyltransferase subunit CysD 0.50 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase 0.87 3
Pectobacterium carotovorum WPP14 0.94 HER17_RS04285 sulfate adenylyltransferase subunit CysD 0.72 HER17_RS01835 siroheme synthase CysG low > 75
Rahnella sp. WP5 0.94 EX31_RS07880 sulfate adenylyltransferase subunit CysD 0.71 EX31_RS04680 uroporphyrinogen-III C-methyltransferase low > 89
Pantoea sp. MT58 0.94 IAI47_04180 sulfate adenylyltransferase subunit CysD 0.50 IAI47_04175 uroporphyrinogen-III C-methyltransferase 0.94 2
Serratia liquefaciens MT49 0.93 IAI46_03715 sulfate adenylyltransferase subunit CysD 0.71 IAI46_23670 uroporphyrinogen-III C-methyltransferase low > 86
Erwinia tracheiphila SCR3 0.90 LU632_RS06425 cysD sulfate adenylyltransferase subunit CysD 0.53 LU632_RS06420 cysG siroheme synthase CysG 0.97 2
Pseudomonas fluorescens FW300-N2C3 0.77 AO356_16665 sulfate adenylyltransferase 0.49 AO356_22200 sirohydrochlorin ferrochelatase 0.80 2
Pseudomonas fluorescens FW300-N2E2 0.77 Pf6N2E2_5257 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) 0.49 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.50 18
Acinetobacter radioresistens SK82 0.77 MPMX26_02326 Sulfate adenylyltransferase subunit 2 0.45 MPMX26_00706 Siroheme synthase — —
Pseudomonas putida KT2440 0.77 PP_1303 Sulfate adenylyltransferase subunit 2 0.47 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase 0.51 16
Pseudomonas sp. RS175 0.77 PFR28_00193 Sulfate adenylyltransferase subunit 2 0.49 PFR28_02603 Siroheme synthase 0.38 32
Pseudomonas fluorescens SBW25 0.77 PFLU_RS03765 sulfate adenylyltransferase subunit CysD 0.48 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.59 88
Pseudomonas fluorescens FW300-N2E3 0.77 AO353_05080 sulfate adenylyltransferase 0.49 AO353_27625 sirohydrochlorin ferrochelatase — —
Pseudomonas sp. S08-1 0.77 OH686_08450 Sulfate adenylyltransferase subunit 2 0.45 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.77 PFLU_RS03765 sulfate adenylyltransferase subunit CysD 0.48 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.57 5
Pseudomonas simiae WCS417 0.77 PS417_03715 sulfate adenylyltransferase subunit 2 0.48 PS417_16465 sirohydrochlorin ferrochelatase — —
Pseudomonas fluorescens GW456-L13 0.76 PfGW456L13_4993 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) 0.49 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.77 3
Pseudomonas syringae pv. syringae B728a ΔmexB 0.76 Psyr_4128 sulfate adenylyltransferase subunit 2 0.49 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase 0.65 64
Pseudomonas syringae pv. syringae B728a 0.76 Psyr_4128 sulfate adenylyltransferase subunit 2 0.49 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase 0.82 6
Pseudomonas stutzeri RCH2 0.76 Psest_3294 sulfate adenylyltransferase, small subunit 0.51 Psest_2037 uroporphyrin-III C-methyltransferase — —
Alteromonas macleodii MIT1002 0.76 MIT1002_01274 Sulfate adenylyltransferase subunit 2 0.45 MIT1002_00665 Siroheme synthase — —
Pseudomonas fluorescens FW300-N1B4 0.75 Pf1N1B4_1058 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) 0.49 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) — —
Kangiella aquimarina DSM 16071 0.75 B158DRAFT_2360 sulfate adenylyltransferase, small subunit 0.49 B158DRAFT_2163 uroporphyrin-III C-methyltransferase low > 40
Brevundimonas sp. GW460-12-10-14-LB2 0.74 A4249_RS15305 sulfate adenylyltransferase subunit CysD 0.31 A4249_RS09675 siroheme synthase CysG 0.99 6
Sinorhizobium meliloti 1021 0.69 SMc00091 sulfate adenylyltransferase 0.32 SMc01053 siroheme synthase 0.97 4
Rhodospirillum rubrum S1H 0.69 Rru_A2289 Sulfate adenylyltransferase, small subunit (NCBI) 0.27 Rru_A1933 Uroporphyrin-III C-methyltransferase (NCBI) — —
Agrobacterium fabrum C58 0.69 Atu0817 sulfate adenylate transferase, subunit 2 0.33 Atu3899 siroheme synthase low > 89
Rhizobium sp. OAE497 0.68 ABIE40_RS04470 sulfate adenylyltransferase subunit CysD 0.31 ABIE40_RS09140 siroheme synthase CysG 0.89 3
Rhodanobacter sp. FW510-T8 0.68 OKGIIK_01295 cysD sulfate adenylyltransferase subunit CysD 0.40 OKGIIK_05980 cysG siroheme synthase CysG low > 52
Lysobacter sp. OAE881 0.68 ABIE51_RS15820 sulfate adenylyltransferase subunit CysD 0.43 ABIE51_RS15855 siroheme synthase CysG 0.97 17
Rhodanobacter denitrificans FW104-10B01 0.67 LRK54_RS05520 sulfate adenylyltransferase subunit CysD 0.38 LRK54_RS00910 siroheme synthase CysG low > 59
Rhodanobacter denitrificans MT42 0.67 LRK55_RS05290 sulfate adenylyltransferase subunit CysD 0.37 LRK55_RS00685 siroheme synthase CysG — —
Dyella japonica UNC79MFTsu3.2 0.64 ABZR86_RS18865 sulfate adenylyltransferase subunit CysD 0.44 ABZR86_RS05880 siroheme synthase CysG 0.28 63
Bosea sp. OAE506 0.64 ABIE41_RS15370 sulfate adenylyltransferase subunit CysD 0.26 ABIE41_RS15910 siroheme synthase CysG — —
Mycobacterium tuberculosis H37Rv 0.47 Rv1285 Probable sulfate adenylyltransferase subunit 2 CysD 0.20 Rv2847c Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase — —
Castellaniella sp019104865 MT123 0.45 ABCV34_RS14115 sulfate adenylyltransferase subunit CysD 0.40 ABCV34_RS00210 siroheme synthase CysG low > 48
Rhodopseudomonas palustris CGA009 0.32 TX73_003885 sulfate adenylyltransferase subunit 2 0.30 TX73_021850 siroheme synthase CysG 0.78 5

Not shown: 39 genomes with orthologs for b2752 only; 1 genomes with orthologs for b3368 only