| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b3867 | hemN | O2-independent coproporphyrinogen III oxidase (VIMSS) | 1.0 | b3052 | rfaE | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | 0.47 | 7 |
| Escherichia coli BL21 | 1.00 | ECD_03752 | | coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent | 1.00 | ECD_02922 | | heptose 7-phosphate kinase and heptose 1-phosphate adenyltransferase | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_17745 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | JDDGAC_22370 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_04620 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | MCAODC_09250 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC62 | 1.00 | BNILDI_05280 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | BNILDI_00995 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_06250 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | NOLOHH_10520 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_14030 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | KEDOAH_09410 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_04186 | | Oxygen-independent coproporphyrinogen III oxidase | 1.00 | OHPLBJKB_00652 | | Bifunctional protein HldE | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_14120 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | OKFHMN_18735 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_11875 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | NIAGMN_16500 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS22285 | | oxygen-independent coproporphyrinogen III oxidase | 1.00 | ECOLIN_RS17615 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | low | > 52 |
| Escherichia coli ECOR38 | 0.99 | HEPCGN_12755 | hemN | oxygen-independent coproporphyrinogen III oxidase | 1.00 | HEPCGN_17590 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Escherichia fergusonii Becca | 0.99 | EFB2_04750 | | Oxygen-independent coproporphyrinogen III oxidase | 1.00 | EFB2_00759 | | Bifunctional protein HldE | — | — |
| Enterobacter asburiae PDN3 | 0.93 | EX28DRAFT_4348 | | oxygen-independent coproporphyrinogen III oxidase | 0.96 | EX28DRAFT_3080 | | rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.93 | GFF2219 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | 0.95 | GFF3166 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | low | > 78 |
| Enterobacter sp. TBS_079 | 0.93 | MPMX20_04598 | | Oxygen-independent coproporphyrinogen III oxidase | 0.96 | MPMX20_03889 | | Bifunctional protein HldE | — | — |
| Klebsiella michiganensis M5al | 0.90 | BWI76_RS00380 | | oxygen-independent coproporphyrinogen III oxidase | 0.94 | BWI76_RS24455 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase | — | — |
| Pectobacterium carotovorum WPP14 | 0.83 | HER17_RS21450 | | oxygen-independent coproporphyrinogen III oxidase | 0.86 | HER17_RS04040 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Serratia liquefaciens MT49 | 0.82 | IAI46_24970 | | oxygen-independent coproporphyrinogen III oxidase | 0.85 | IAI46_22055 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Dickeya dianthicola ME23 | 0.80 | DZA65_RS22220 | | oxygen-independent coproporphyrinogen III oxidase | 0.83 | DZA65_RS18235 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Dickeya dadantii 3937 | 0.79 | DDA3937_RS00120 | | oxygen-independent coproporphyrinogen III oxidase | 0.83 | DDA3937_RS17100 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Dickeya dianthicola 67-19 | 0.79 | HGI48_RS21245 | | oxygen-independent coproporphyrinogen III oxidase | 0.83 | HGI48_RS17150 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Rahnella sp. WP5 | 0.79 | EX31_RS15885 | | oxygen-independent coproporphyrinogen III oxidase | 0.84 | EX31_RS08140 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | low | > 89 |
| Pantoea sp. MT58 | 0.76 | IAI47_00445 | | oxygen-independent coproporphyrinogen III oxidase | 0.83 | IAI47_03105 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.71 | CSW01_00590 | | oxygen-independent coproporphyrinogen III oxidase | 0.67 | CSW01_12340 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase | low | > 62 |
| Erwinia tracheiphila SCR3 | 0.70 | LU632_RS22115 | hemN | oxygen-independent coproporphyrinogen III oxidase | 0.82 | LU632_RS20670 | hldE | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Shewanella oneidensis MR-1 | 0.67 | SO4730 | hemN | oxygen-independent coproporphyrinogen III oxidase (NCBI ptt file) | 0.60 | SO3745 | rfaE | ADP-heptose synthase (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.66 | Shewana3_4116 | | coproporphyrinogen III oxidase (RefSeq) | 0.61 | Shewana3_0849 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) | low | > 73 |
| Shewanella amazonensis SB2B | 0.66 | Sama_0086 | | coproporphyrinogen III oxidase (RefSeq) | 0.58 | Sama_0731 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) | — | — |
| Shewanella loihica PV-4 | 0.66 | Shew_3720 | | coproporphyrinogen III oxidase (RefSeq) | 0.58 | Shew_0659 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (RefSeq) | low | > 60 |
| Kangiella aquimarina DSM 16071 | 0.53 | B158DRAFT_1981 | | coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) | 0.54 | B158DRAFT_1987 | | D-alpha,beta-D-heptose 7-phosphate 1-kinase (EC 2.7.1.167)/D-beta-D-heptose 1-phosphate adenylyltransferase (EC 2.7.7.70) | low | > 40 |
| Pseudomonas fluorescens GW456-L13 | 0.49 | PfGW456L13_4070 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | 0.55 | PfGW456L13_195 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | — | — |
| Pseudomonas sp. RS175 | 0.49 | PFR28_01080 | | Oxygen-independent coproporphyrinogen III oxidase | 0.56 | PFR28_05083 | | Bifunctional protein HldE | — | — |
| Pseudomonas simiae WCS417 | 0.49 | PS417_20775 | | coproporphyrinogen III oxidase | 0.56 | PS417_02310 | | heptose 1-phosphate adenyltransferase | — | — |
| Pseudomonas fluorescens SBW25 | 0.49 | PFLU_RS22385 | | oxygen-independent coproporphyrinogen III oxidase | 0.56 | PFLU_RS02385 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.49 | PFLU_RS22385 | | oxygen-independent coproporphyrinogen III oxidase | 0.56 | PFLU_RS02385 | | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.48 | Pf1N1B4_3868 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | 0.55 | Pf1N1B4_1455 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | — | — |
| Pseudomonas sp. S08-1 | 0.48 | OH686_02235 | | oxygen-independent coproporphyrinogen III oxidase | 0.55 | OH686_09595 | | D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase / D-glycero-beta-D-manno-heptose-7-phosphate kinase | — | — |
| Pseudomonas putida KT2440 | 0.48 | PP_4264 | | oxygen-independent coproporphyrinogen III dehydrogenase | 0.54 | PP_4934 | | heptose 7-phosphate kinase/heptose 1-phosphate adenylyltransferase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.48 | Psyr_3423 | | coproporphyrinogen III oxidase, anaerobic | 0.56 | Psyr_0537 | | D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.48 | Psyr_3423 | | coproporphyrinogen III oxidase, anaerobic | 0.56 | Psyr_0537 | | D-alpha,beta-D-heptose 7-phosphate 1-kinase / D-beta-D-heptose 1-phosphate adenylyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.48 | AO353_00655 | | coproporphyrinogen III oxidase | 0.55 | AO353_12970 | | heptose 1-phosphate adenyltransferase | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.48 | Pf6N2E2_2321 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | 0.55 | Pf6N2E2_3653 | | ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.48 | AO356_02480 | | coproporphyrinogen III oxidase | 0.55 | AO356_08850 | | heptose 1-phosphate adenyltransferase | — | — |
| Pseudomonas stutzeri RCH2 | 0.47 | Psest_2537 | | oxygen-independent coproporphyrinogen III oxidase | 0.57 | Psest_0470 | | rfaE bifunctional protein, domain I/rfaE bifunctional protein, domain II | — | — |
| Rhodospirillum rubrum S1H | 0.34 | Rru_A2504 | | Oxygen-independent coproporphyrinogen III oxidase HemN (NCBI) | 0.35 | Rru_A0123 | | RfaE-HldE bifunctional protein, D-beta-D-heptose 7-phosphate kinase, D-beta-D-heptose 1-phosphate adenosyltransferase (NCBI) | — | — |
| Azospirillum sp. SherDot2 | 0.34 | MPMX19_02313 | | Oxygen-independent coproporphyrinogen III oxidase | 0.35 | MPMX19_02117 | | Bifunctional protein HldE | — | — |
| Rhodopseudomonas palustris CGA009 | 0.33 | TX73_008565 | | oxygen-independent coproporphyrinogen III oxidase | 0.32 | TX73_020645 | | D-glycero-beta-D-manno-heptose-7-phosphate kinase | — | — |
| Azospirillum brasilense Sp245 | 0.33 | AZOBR_RS03710 | | coproporphyrinogen III oxidase | 0.37 | AZOBR_RS33905 | | D-beta-D-heptose 1-phosphate adenosyltransferase | low | > 97 |
| Magnetospirillum magneticum AMB-1 | 0.33 | AMB_RS13570 | | oxygen-independent coproporphyrinogen III oxidase | 0.33 | AMB_RS03985 | | bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase | — | — |
| Caulobacter crescentus NA1000 | 0.27 | CCNA_01477 | | oxygen-independent coproporphyrinogen-III oxidase hemN | 0.34 | CCNA_03755 | | bifunctional D-glycero-D-manno-heptose-7-phosphate 1-kinase/D-glycero-D-manno-heptose-1-phosphate adenylyltransferase | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.27 | CCNA_01477 | | oxygen-independent coproporphyrinogen-III oxidase hemN | 0.34 | CCNA_03755 | | bifunctional D-glycero-D-manno-heptose-7-phosphate 1-kinase/D-glycero-D-manno-heptose-1-phosphate adenylyltransferase | low | > 67 |
Not shown: 36 genomes with orthologs for b3867 only; 1 genomes with orthologs for b3052 only