Conservation of cofitness between b0945 and b2476 in Escherichia coli BW25113

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 1.0 b2476 purC phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) 0.88 14
Escherichia coli ECRC98 1.00 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 JDDGAC_25875 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Escherichia coli ECRC101 1.00 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 MCAODC_12460 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Escherichia coli ECRC99 1.00 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 KEDOAH_06290 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Escherichia coli ECRC101 1.00 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 OKFHMN_21930 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Escherichia coli ECOR27 1.00 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 NOLOHH_13590 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Escherichia coli BL21 1.00 ECD_00949 dihydro-orotate oxidase, FMN-linked 1.00 ECD_02368 phosphoribosylaminoimidazole-succinocarboxamide synthetase — —
Escherichia coli ECRC62 1.00 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 BNILDI_12400 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Escherichia coli ECRC102 1.00 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 NIAGMN_19700 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 1.00 OHPLBJKB_01254 Phosphoribosylaminoimidazole-succinocarboxamide synthase low > 73
Escherichia coli ECOR38 1.00 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 HEPCGN_21100 purC phosphoribosylaminoimidazolesuccinocarboxamide synthase low > 85
Escherichia fergusonii Becca 0.99 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 1.00 EFB2_01411 Phosphoribosylaminoimidazole-succinocarboxamide synthase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 1.00 ECOLIN_RS14130 phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.97 GFF2182 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.97 EX28DRAFT_0184 phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) — —
Enterobacter sp. TBS_079 0.94 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.97 MPMX20_03338 Phosphoribosylaminoimidazole-succinocarboxamide synthase 0.82 29
Klebsiella michiganensis M5al 0.93 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.96 BWI76_RS20895 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.67 11
Serratia liquefaciens MT49 0.87 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.91 IAI46_18770 phosphoribosylaminoimidazolesuccinocarboxamide synthase low > 86
Rahnella sp. WP5 0.86 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.92 EX31_RS22750 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.92 47
Pectobacterium carotovorum WPP14 0.86 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.91 HER17_RS15405 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.93 38
Dickeya dianthicola ME23 0.86 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.89 DZA65_RS06470 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.61 71
Dickeya dadantii 3937 0.86 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.90 DDA3937_RS06075 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.71 18
Dickeya dianthicola 67-19 0.85 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.89 HGI48_RS06120 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.78 13
Erwinia tracheiphila SCR3 0.84 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.88 LU632_RS08335 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.71 55
Pantoea sp. MT58 0.81 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.90 IAI47_05275 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.96 12
Alteromonas macleodii MIT1002 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.71 MIT1002_02205 Phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.68 PFLU_RS07290 phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Pseudomonas fluorescens SBW25 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.68 PFLU_RS07290 phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.71 Pf1N1B4_3335 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) — —
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.73 AO353_17685 phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Pseudomonas simiae WCS417 0.57 PS417_20935 dihydroorotate dehydrogenase 0.68 PS417_07180 phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_2106 dihydroorotate oxidase A 0.74 Psyr_1551 phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_2106 dihydroorotate oxidase A 0.74 Psyr_1551 phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Pseudomonas sp. RS175 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.71 PFR28_00702 Phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.67 Pf6N2E2_2744 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) — —
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.71 PfGW456L13_4504 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) — —
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.68 AO356_04515 phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Pseudomonas putida KT2440 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.72 PP_1240 Phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Acinetobacter radioresistens SK82 0.53 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.61 MPMX26_02984 Phosphoribosylaminoimidazole-succinocarboxamide synthase 0.76 32
Marinobacter adhaerens HP15 0.47 HP15_1377 dihydroorotate dehydrogenase 0.70 HP15_2025 phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Sinorhizobium meliloti 1021 0.40 SMc02245 dihydroorotate dehydrogenase 2 0.45 SMc00495 phosphoribosylaminoimidazolesuccinocarboxamide synthase 0.91 7
Agrobacterium fabrum C58 0.40 Atu0486 dihydroorotate dehydrogenase 0.44 Atu1843 phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.39 Ga0059261_1526 phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) — —
Rhizobium sp. OAE497 0.38 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.44 ABIE40_RS10140 phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.38 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.41 A4249_RS00890 phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Rhodopseudomonas palustris CGA009 0.37 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.43 TX73_019780 phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Azospirillum sp. SherDot2 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.43 MPMX19_00448 Phosphoribosylaminoimidazole-succinocarboxamide synthase — —
Azospirillum brasilense Sp245 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.43 AZOBR_RS04370 phosphoribosylaminoimidazole-succinocarboxamide synthase 0.55 37
Magnetospirillum magneticum AMB-1 0.36 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase 0.43 AMB_RS07775 phosphoribosylaminoimidazolesuccinocarboxamide synthase — —
Rhodospirillum rubrum S1H 0.36 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.42 Rru_A0711 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.33 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.41 PGA1_c13400 phosphoribosylaminoimidazole-succinocarboxamide synthase PurC 0.83 24
Bosea sp. OAE506 0.33 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.44 ABIE41_RS05015 phosphoribosylaminoimidazolesuccinocarboxamide synthase low > 77
Dinoroseobacter shibae DFL-12 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.40 Dshi_1076 phosphoribosylaminoimidazole-succinocarboxamidesynthase (RefSeq) 0.75 23
Caulobacter crescentus NA1000 Δfur 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.41 CCNA_02576 phosphoribosylamidoimidazole-succinocarboxamide synthase low > 67
Caulobacter crescentus NA1000 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.41 CCNA_02576 phosphoribosylamidoimidazole-succinocarboxamide synthase low > 66
Bifidobacterium breve UCC2003 0.22 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.39 BBR_RS13450 phosphoribosylaminoimidazolesuccinocarboxamide synthase low > 34

Not shown: 37 genomes with orthologs for b0945 only; 4 genomes with orthologs for b2476 only