| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Sinorhizobium meliloti 1021 | SMa2143 | | 5,10-methylenetetrahydrofolate reductase | insig. | 100 | 100 |
| o | Agrobacterium fabrum C58 | Atu1764 | | methylenetetrahydrofolate reductase | sig. | 33 | 82 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.399.1 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | insig. | 30 | 83 |
| o | Phaeobacter inhibens DSM 17395 | PGA1_c16050 | | 5,10-methylenetetrahydrofolate reductase | strong | 33 | 82 |
| o | Variovorax sp. SCN45 | GFF4178 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | insig. | 29 | 83 |
| | Agrobacterium fabrum C58 | Atu1418 | | methylenetetrahydrofolate reductase | sig. | 30 | 82 |
| o | Dinoroseobacter shibae DFL-12 | Dshi_1675 | | MetF protein-like protein (RefSeq) | strong | 32 | 82 |
| | Rhizobium sp. OAE497 | ABIE40_RS20900 | | methylenetetrahydrofolate reductase | insig. | 32 | 77 |
| | Azospirillum brasilense Sp245 | AZOBR_RS24245 | | 5 10-methylenetetrahydrofolate reductase | insig. | 29 | 62 |
| | Shewanella amazonensis SB2B | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | strong | 32 | 63 |
| | Paraburkholderia graminis OAS925 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | strong | 29 | 64 |
| | Shewanella sp. ANA-3 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | strong | 31 | 63 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | insig. | 28 | 66 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS02230 | | methylenetetrahydrofolate reductase | no data | 38 | 26 |
| | Agrobacterium fabrum C58 | Atu2123 | | methylenetetrahydrofolate reductase | strong | 32 | 44 |
| | Shewanella oneidensis MR-1 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | strong | 30 | 63 |
| | Azospirillum sp. SherDot2 | MPMX19_00635 | | 5,10-methylenetetrahydrofolate reductase | strong | 33 | 37 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | strong | 27 | 64 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | strong | 28 | 64 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS23495 | | methylenetetrahydrofolate reductase [NAD(P)H] | strong | 26 | 65 |
| | Azospirillum brasilense Sp245 | AZOBR_RS09540 | | 5 10-methylenetetrahydrofolate reductase | cofit | 32 | 37 |
| | Shewanella loihica PV-4 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | strong | 30 | 50 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS09875 | | methylenetetrahydrofolate reductase [NAD(P)H] | strong | 26 | 65 |
| | Ralstonia solanacearum UW163 | UW163_RS03705 | | methylenetetrahydrofolate reductase [NAD(P)H] | insig. | 26 | 65 |
| | Rhizobium sp. OAE497 | ABIE40_RS11950 | | methylenetetrahydrofolate reductase [NAD(P)H] | strong | 32 | 35 |
| | Sinorhizobium meliloti 1021 | SMc01843 | | 5,10-methylenetetrahydrofolate reductase | strong | 34 | 26 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_16780 | | methylenetetrahydrofolate reductase [NAD(P)H] | insig. | 33 | 45 |
| | Ralstonia solanacearum GMI1000 | RS_RS00460 | | methylenetetrahydrofolate reductase [NAD(P)H] | strong | 26 | 65 |
| | Rhodospirillum rubrum S1H | Rru_A1530 | | 5,10-methylenetetrahydrofolate reductase (NCBI) | strong | 30 | 41 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS04865 | | methylenetetrahydrofolate reductase [NAD(P)H] | strong | 26 | 65 |
| | Erwinia amylovora T8 | OLJFJH_06105 | | methylenetetrahydrofolate reductase | strong | 31 | 49 |
| | Dickeya dianthicola 67-19 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | insig. | 29 | 49 |
| | Alteromonas macleodii MIT1002 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | strong | 29 | 49 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | strong | 26 | 51 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_13605 | | 5,10-methylenetetrahydrofolate reductase | strong | 27 | 52 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_13030 | metF | methylenetetrahydrofolate reductase | insig. | 30 | 49 |
| | Erwinia tracheiphila SCR3 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | insig. | 30 | 49 |
| | Dickeya dianthicola ME23 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | cofit | 29 | 49 |
| | Pseudomonas sp. RS175 | PFR28_04202 | | 5,10-methylenetetrahydrofolate reductase | strong | 27 | 52 |
| | Marinobacter adhaerens HP15 | HP15_2917 | | 5,10-methylenetetrahydrofolate reductase-like protein | strong | 22 | 70 |