| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1419 | atoC | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | sig. | 100 | 100 |
| o | Desulfovibrio vulgaris Miyazaki F | DvMF_0215 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 68 | 100 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3220 | atoC | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | no data | 46 | 99 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0823 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | insig. | 46 | 98 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2200 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | no data | 45 | 99 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2149 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 47 | 98 |
| | Pseudomonas orientalis W4I3 | QF045_RS08450 | | sigma-54 dependent transcriptional regulator | insig. | 44 | 99 |
| o | Methylophilus sp. DMC18 | GFF2815 | | Regulatory protein AtoC | insig. | 44 | 98 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_16225 | | Fis family transcriptional regulator | insig. | 44 | 99 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01292 | | Regulatory protein AtoC | cofit | 44 | 99 |
| | Pseudomonas simiae WCS417 | PS417_05525 | | Fis family transcriptional regulator | strong | 44 | 99 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS05610 | | sigma-54-dependent Fis family transcriptional regulator | strong | 44 | 99 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS05610 | | sigma-54-dependent Fis family transcriptional regulator | strong | 44 | 99 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3381 | ntrC | transcriptional regulatory protein zraR (TIGR) | strong | 47 | 98 |
| | Klebsiella michiganensis M5al | BWI76_RS01605 | | transcriptional regulatory protein ZraR | insig. | 46 | 98 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_04045 | | Transcriptional regulatory protein ZraR | insig. | 44 | 98 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS23090 | | sigma-54-dependent response regulator transcription factor ZraR | insig. | 44 | 98 |
| | Escherichia coli ECRC62 | BNILDI_06055 | zraR | sigma-54-dependent response regulator transcription factor ZraR | insig. | 44 | 98 |
| | Escherichia fergusonii Becca | EFB2_04606 | | Transcriptional regulatory protein ZraR | insig. | 44 | 98 |
| | Escherichia coli ECOR38 | HEPCGN_11960 | zraR | sigma-54-dependent response regulator transcription factor ZraR | insig. | 44 | 98 |
| | Escherichia coli ECOR27 | NOLOHH_05465 | zraR | sigma-54-dependent response regulator transcription factor ZraR | insig. | 43 | 98 |
| | Escherichia coli BW25113 | b4004 | zraR | fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein (NCBI) | insig. | 44 | 98 |
| | Escherichia coli ECOR38 | HEPCGN_22430 | atoC | acetoacetate metabolism transcriptional regulator AtoC | insig. | 43 | 99 |
| | Escherichia fergusonii Becca | EFB2_01635 | | Regulatory protein AtoC | insig. | 43 | 99 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS12965 | | acetoacetate metabolism transcriptional regulator AtoC | no data | 43 | 99 |
| | Escherichia coli BL21 | ECD_03881 | | fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein | insig. | 44 | 98 |
| | Escherichia coli BL21 | ECD_02147 | | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein | insig. | 43 | 99 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01490 | | Regulatory protein AtoC | insig. | 43 | 99 |
| | Escherichia coli BW25113 | b2220 | atoC | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein (NCBI) | insig. | 43 | 99 |
| | Escherichia coli ECRC100 | OKFHMN_13320 | zraR | sigma-54-dependent response regulator transcription factor ZraR | cofit | 43 | 98 |
| | Escherichia coli ECRC101 | MCAODC_03820 | zraR | sigma-54-dependent response regulator transcription factor ZraR | insig. | 43 | 98 |
| | Escherichia coli ECRC102 | NIAGMN_11070 | zraR | sigma-54-dependent response regulator transcription factor ZraR | insig. | 43 | 98 |
| | Escherichia coli ECRC99 | KEDOAH_14840 | zraR | sigma-54-dependent response regulator transcription factor ZraR | no data | 43 | 98 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1461 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | no data | 48 | 84 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2934 | ntrX | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | no data | 42 | 96 |
| | Rhodospirillum rubrum S1H | Rru_A1385 | | Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) | cofit | 43 | 99 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_10090 | | sigma-54-dependent response regulator transcription factor ZraR | insig. | 44 | 98 |
| | Escherichia coli ECRC98 | JDDGAC_16945 | zraR | sigma-54-dependent response regulator transcription factor ZraR | insig. | 43 | 98 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4188 | | Response regulator of zinc sigma-54-dependent two-component system | insig. | 43 | 98 |
| | Xanthobacter sp. DMC5 | GFF4834 | | Regulatory protein AtoC | insig. | 43 | 98 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS12650 | | sigma-54 dependent transcriptional regulator | insig. | 41 | 99 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2455 | | Putative sensory histidine kinase YfhA | strong | 47 | 84 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0110 | ntrC | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | cofit | 42 | 99 |
| | Escherichia fergusonii Becca | EFB2_01342 | | Transcriptional regulatory protein QseF | insig. | 47 | 84 |
| | Escherichia coli ECOR27 | NOLOHH_13170 | qseF | two-component system response regulator QseF/GlrR | cofit | 47 | 84 |
| | Escherichia coli ECRC62 | BNILDI_11970 | qseF | two-component system response regulator QseF/GlrR | strong | 47 | 84 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01153 | | Transcriptional regulatory protein GlrR | insig. | 47 | 84 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09510 | | sigma-54-dependent Fis family transcriptional regulator | sig. | 40 | 99 |
| | Escherichia coli ECOR38 | HEPCGN_20640 | qseF | two-component system response regulator QseF/GlrR | strong | 47 | 84 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0946 | | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | sig. | 42 | 99 |
| | Escherichia coli BL21 | ECD_02446 | | response regulator regulating glmY sRNA in two-component system with sensor protein GlrK | sig. | 47 | 84 |
| | Escherichia coli ECRC100 | OKFHMN_21495 | qseF | two-component system response regulator QseF/GlrR | cofit | 47 | 84 |
| | Escherichia coli ECRC101 | MCAODC_12025 | qseF | two-component system response regulator QseF/GlrR | cofit | 47 | 84 |
| | Escherichia coli ECRC102 | NIAGMN_19265 | qseF | two-component system response regulator QseF/GlrR | cofit | 47 | 84 |
| | Escherichia coli ECRC98 | JDDGAC_25160 | qseF | two-component system response regulator QseF/GlrR | cofit | 47 | 84 |
| | Escherichia coli ECRC99 | KEDOAH_06725 | qseF | two-component system response regulator QseF/GlrR | no data | 47 | 84 |
| | Escherichia coli BW25113 | b2554 | yfhA | predicted DNA-binding response regulator in two-component system (NCBI) | sig. | 47 | 84 |
| | Methylophilus sp. DMC18 | GFF1426 | | Transcriptional regulatory protein ZraR | insig. | 43 | 99 |
| o | Enterobacter sp. TBS_079 | MPMX20_03423 | | Transcriptional regulatory protein QseF | sig. | 46 | 84 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1993 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | sig. | 42 | 99 |
| o | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS01040 | | sigma-54-dependent Fis family transcriptional regulator | insig. | 40 | 98 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS14455 | | two-component system response regulator GlrR | strong | 47 | 84 |
| | Azospirillum sp. SherDot2 | MPMX19_03461 | | Regulatory protein AtoC | insig. | 42 | 99 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0700 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | insig. | 42 | 98 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_0096 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | sig. | 46 | 84 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_04380 | | response regulator | strong | 44 | 83 |
| | Azospirillum sp. SherDot2 | MPMX19_04251 | | C4-dicarboxylate transport transcriptional regulatory protein DctD | insig. | 42 | 99 |
| o | Cellulophaga baltica 18 | M666_RS03195 | | sigma-54 dependent transcriptional regulator | insig. | 38 | 99 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS30045 | | ATPase AAA | insig. | 42 | 99 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS10015 | | sigma-54 dependent transcriptional regulator | sig. | 39 | 100 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2109 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 41 | 98 |
| | Klebsiella michiganensis M5al | BWI76_RS21250 | | two-component system response regulator GlrR | sig. | 46 | 83 |
| o | Caulobacter crescentus NA1000 | CCNA_03424 | | AAA-family response regulator tacA | strong | 40 | 99 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_03424 | | AAA-family response regulator tacA | cofit | 40 | 99 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1260 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | insig. | 42 | 99 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2114 | atoC | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | insig. | 41 | 99 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS09115 | | sigma-54 dependent transcriptional regulator | insig. | 41 | 99 |
| | Serratia liquefaciens MT49 | IAI46_19460 | | two-component system response regulator GlrR | sig. | 45 | 82 |
| o | Lysobacter sp. OAE881 | ABIE51_RS04850 | | sigma-54 dependent transcriptional regulator | strong | 41 | 99 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS09195 | | Fis family transcriptional regulator | strong | 39 | 100 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_28370 | | two-component system response regulator QseF/GlrR | insig. | 45 | 83 |
| o | Agrobacterium fabrum C58 | Atu0114 | | two component response regulator | insig. | 40 | 100 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS14380 | | sigma-54 dependent transcriptional regulator | insig. | 39 | 99 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2095 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | sig. | 42 | 98 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_4019 | | Sigma-54 dependent transcriptional regulator | sig. | 41 | 99 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS23170 | | ATPase AAA | insig. | 43 | 99 |
| | Pseudomonas stutzeri RCH2 | Psest_0705 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 42 | 98 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0539 | | sigma-54 dependent DNA-binding response regulator (TIGR) | sig. | 41 | 99 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_01779 | | DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains | insig. | 41 | 99 |
| | Cellulophaga baltica 18 | M666_RS19210 | | sigma-54 dependent transcriptional regulator | insig. | 42 | 83 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS18445 | | chemotaxis protein CheY | insig. | 41 | 98 |
| | Pseudomonas sp. SVBP6 | COO64_RS07975 | | sigma-54 dependent transcriptional regulator | insig. | 43 | 99 |
| | Azospirillum brasilense Sp245 | AZOBR_RS21130 | | Fis family transcriptional regulator | insig. | 41 | 99 |
| | Dickeya dianthicola 67-19 | HGI48_RS15735 | | two-component system response regulator GlrR | insig. | 46 | 81 |
| | Variovorax sp. SCN45 | GFF3669 | | Two-component system response regulator protein | no data | 41 | 99 |
| | Rahnella sp. WP5 | EX31_RS20615 | | two-component system response regulator GlrR | insig. | 44 | 86 |
| | Azospirillum sp. SherDot2 | MPMX19_03494 | | Regulatory protein AtoC | insig. | 42 | 98 |
| o | Pseudomonas sp. S08-1 | OH686_17260 | | Two-component sensor CbrB: intrcellular carbon:nitrogen balance | strong | 39 | 100 |
| | Dickeya dianthicola ME23 | DZA65_RS16815 | | two-component system response regulator GlrR | insig. | 45 | 81 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1353.1 | | Type IV fimbriae expression regulatory protein PilR | sig. | 42 | 94 |