| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Pseudomonas syringae pv. syringae B728a | 1.0 | Psyr_3459 | | Helix-turn-helix, Fis-type | 1.0 | Psyr_0033 | | tryptophan synthase, alpha chain | 0.40 | 18 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 1.00 | Psyr_3459 | | Helix-turn-helix, Fis-type | 1.00 | Psyr_0033 | | tryptophan synthase, alpha chain | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.82 | PfGW456L13_4355 | | Flagellar regulatory protein FleQ | 0.81 | PfGW456L13_565 | | Tryptophan synthase alpha chain (EC 4.2.1.20) | low | > 87 |
| Pseudomonas sp. DMC3 | 0.82 | GFF2447 | | Regulatory protein AtoC | 0.82 | GFF677 | | Tryptophan synthase alpha chain | low | > 89 |
| Pseudomonas fluorescens FW300-N2E3 | 0.81 | AO353_18670 | | Fis family transcriptional regulator | 0.81 | AO353_10705 | | tryptophan synthase subunit alpha | low | > 101 |
| Pseudomonas fluorescens FW300-N2E2 | 0.81 | Pf6N2E2_2595 | | Flagellar regulatory protein FleQ | 0.80 | Pf6N2E2_4047 | | Tryptophan synthase alpha chain (EC 4.2.1.20) | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.80 | AO356_03845 | | Fis family transcriptional regulator | 0.81 | AO356_10910 | | tryptophan synthase subunit alpha | low | > 104 |
| Pseudomonas fluorescens SBW25-INTG | 0.80 | PFLU_RS21785 | | sigma-54-dependent Fis family transcriptional regulator | 0.82 | PFLU_RS00175 | | tryptophan synthase subunit alpha | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.80 | PFLU_RS21785 | | sigma-54-dependent Fis family transcriptional regulator | 0.82 | PFLU_RS00175 | | tryptophan synthase subunit alpha | low | > 109 |
| Pseudomonas sp. RS175 | 0.80 | PFR28_00830 | | Regulatory protein AtoC | 0.80 | PFR28_04716 | | Tryptophan synthase alpha chain | — | — |
| Pseudomonas orientalis W4I3 | 0.80 | QF045_RS21945 | | sigma-54 dependent transcriptional regulator | 0.82 | QF045_RS03115 | | tryptophan synthase subunit alpha | low | > 93 |
| Pseudomonas simiae WCS417 | 0.80 | PS417_19815 | | Fis family transcriptional regulator | 0.82 | PS417_00180 | | tryptophan synthase subunit alpha | — | — |
| Pseudomonas lactucae CFBP13502 | 0.80 | GEMAOFIL_04161 | | Regulatory protein AtoC | 0.81 | GEMAOFIL_00241 | | Tryptophan synthase alpha chain | low | > 96 |
| Pseudomonas sp. SVBP6 | 0.79 | COO64_RS21290 | | sigma-54 dependent transcriptional regulator | 0.89 | COO64_RS02270 | trpA | tryptophan synthase subunit alpha | low | > 93 |
| Pseudomonas sp. S08-1 | 0.75 | OH686_02845 | | Flagellar two-component response regulator FleR | 0.79 | OH686_12430 | | tryptophan synthase, alpha subunit | low | > 80 |
| Pseudomonas sp. BP01 | 0.75 | JOY50_RS00695 | | sigma-54 dependent transcriptional regulator | 0.90 | JOY50_RS21315 | trpA | tryptophan synthase subunit alpha | low | > 84 |
| Pseudomonas segetis P6 | 0.75 | MPMX49_03148 | | Regulatory protein AtoC | 0.79 | MPMX49_00374 | | Tryptophan synthase alpha chain | — | — |
| Pseudomonas putida KT2440 | 0.75 | PP_4371 | | two component system AtoC DNA-binding transcriptional activator | 0.90 | PP_0082 | | tryptophan synthase alpha chain | low | > 96 |
| Pseudomonas aeruginosa PA14 | 0.73 | IKLFDK_05055 | | sigma-54-dependent response regulator transcription factor FleR | 0.76 | IKLFDK_25380 | | tryptophan synthase subunit alpha | low | > 98 |
| Pseudomonas aeruginosa MRSN321 | 0.73 | DY961_RS06955 | fleR;inference=COORDINATES | sigma-54-dependent response regulator transcription factor FleR | 0.76 | DY961_RS26380 | trpA;go_function=tryptophan | tryptophan synthase subunit alpha | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.73 | DQ20_RS45880 | fleR;inference=COORDINATES | sigma-54-dependent response regulator transcription factor FleR | 0.76 | DQ20_RS58785 | trpA;go_function=tryptophan | tryptophan synthase subunit alpha | low | > 101 |
| Pseudomonas stutzeri RCH2 | 0.72 | Psest_1767 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | 0.77 | Psest_0062 | | tryptophan synthase, alpha subunit | low | > 67 |
| Marinobacter adhaerens HP15 | 0.59 | HP15_2328 | | two component, sigma54 specific, transcriptional regulator, Fis family | 0.45 | HP15_1826 | | tryptophan synthase, alpha subunit | — | — |
| Alteromonas macleodii MIT1002 | 0.51 | MIT1002_01083 | | Transcriptional regulatory protein ZraR | 0.30 | MIT1002_01425 | | Tryptophan synthase alpha chain | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.50 | CSW01_10660 | | sigma-54-dependent Fis family transcriptional regulator | 0.28 | CSW01_05925 | | tryptophan synthase subunit alpha | low | > 62 |
| Shewanella oneidensis MR-1 | 0.50 | SO3230 | flrC | flagellar regulatory protein C (NCBI ptt file) | 0.31 | SO3024 | trpA | tryptophan synthase, alpha subunit (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.49 | Shewana3_1340 | | two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) | 0.30 | Shewana3_1515 | trpA | tryptophan synthase subunit alpha (RefSeq) | low | > 73 |
| Shewanella amazonensis SB2B | 0.49 | Sama_2299 | | response regulator receiver protein (RefSeq) | 0.29 | Sama_2134 | trpA | tryptophan synthase subunit alpha (RefSeq) | low | > 62 |
| Shewanella loihica PV-4 | 0.48 | Shew_1364 | | two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) | 0.30 | Shew_2256 | trpA | tryptophan synthase subunit alpha (RefSeq) | low | > 60 |
| Dechlorosoma suillum PS | 0.46 | Dsui_1758 | | response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains | 0.45 | Dsui_3191 | | tryptophan synthase, alpha subunit | — | — |
| Burkholderia phytofirmans PsJN | 0.35 | BPHYT_RS30045 | | ATPase AAA | 0.39 | BPHYT_RS33865 | | tryptophan synthase alpha chain | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.34 | H281DRAFT_01779 | | DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains | 0.39 | H281DRAFT_06065 | | tryptophan synthase, alpha chain | low | > 103 |
| Caulobacter crescentus NA1000 | 0.33 | CCNA_00954 | | AAA-family response regulator flbD | 0.52 | CCNA_03657 | | tryptophan synthase alpha chain | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.33 | CCNA_00954 | | AAA-family response regulator flbD | 0.52 | CCNA_03657 | | tryptophan synthase alpha chain | low | > 67 |
| Magnetospirillum magneticum AMB-1 | 0.33 | AMB_RS02570 | | sigma-54-dependent Fis family transcriptional regulator | 0.59 | AMB_RS20300 | | tryptophan synthase subunit alpha | — | — |
| Rhodospirillum rubrum S1H | 0.32 | Rru_A0540 | | Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) | 0.53 | Rru_A3428 | | Tryptophan synthase (NCBI) | low | > 58 |
| Azospirillum brasilense Sp245 | 0.30 | AZOBR_RS20165 | | ATPase AAA | 0.58 | AZOBR_RS00520 | | tryptophan synthase subunit alpha | low | > 97 |
Not shown: 0 genomes with orthologs for Psyr_3459 only; 86 genomes with orthologs for Psyr_0033 only