Conservation of cofitness between NOLOHH_15540 and NOLOHH_16410 in Escherichia coli ECOR27

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 NOLOHH_16410 tcyJ cystine ABC transporter substrate-binding protein 0.61 5
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 NIAGMN_02260 tcyJ cystine ABC transporter substrate-binding protein
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 KEDOAH_02300 tcyJ cystine ABC transporter substrate-binding protein
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 JDDGAC_00380 tcyJ cystine ABC transporter substrate-binding protein low > 86
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 OKFHMN_25790 tcyJ cystine ABC transporter substrate-binding protein low > 80
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 MCAODC_19600 tcyJ cystine ABC transporter substrate-binding protein low > 87
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.93 ECOLIN_RS10965 cystine ABC transporter substrate-binding protein
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 0.93 b1920 fliY cystine transporter subunit (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 1.00 EFB2_02025 L-cystine-binding protein FliY low > 86
Escherichia coli ECRC62 1.00 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 BNILDI_15200 tcyJ cystine ABC transporter substrate-binding protein low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 0.99 OHPLBJKB_01809 L-cystine-binding protein FliY low > 73
Escherichia coli ECOR38 1.00 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 HEPCGN_04145 tcyJ cystine ABC transporter substrate-binding protein low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF3854 Multidrug transporter MdtB 0.87 GFF1692 Cystine ABC transporter, periplasmic cystine-binding protein FliY low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.85 BWI76_RS18365 cystine ABC transporter substrate-binding protein low > 92
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.87 MPMX20_02845 L-cystine-binding protein FliY low > 85
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0483 Cation/multidrug efflux pump 0.87 EX28DRAFT_0627 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.76 IAI46_15770 cystine ABC transporter substrate-binding protein low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.78 IAI47_08175 cystine ABC transporter substrate-binding protein low > 76
Erwinia tracheiphila SCR3 0.80 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 LU632_RS13770 tcyJ cystine ABC transporter substrate-binding protein low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.27 HER17_RS20280 amino acid ABC transporter substrate-binding protein low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.26 DDA3937_RS01285 amino acid ABC transporter substrate-binding protein low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.25 DZA65_RS01310 amino acid ABC transporter substrate-binding protein low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.26 HGI48_RS01265 amino acid ABC transporter substrate-binding protein low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.37 HSERO_RS10775 cysteine ABC transporter substrate-binding protein low > 78
Ralstonia solanacearum IBSBF1503 0.66 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.24 RALBFv3_RS22445 amino acid ABC transporter substrate-binding protein low > 76
Ralstonia solanacearum UW163 0.66 UW163_RS21010 multidrug transporter subunit MdtB 0.24 UW163_RS22990 amino acid ABC transporter substrate-binding protein
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.24 RPSI07_RS01835 amino acid ABC transporter substrate-binding protein low > 81
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.22 RS_RS19470 amino acid ABC transporter substrate-binding protein low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.34 RR42_RS04395 cysteine ABC transporter substrate-binding protein low > 128
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.57 PFR28_04855 L-cystine-binding protein FliY low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.56 AO356_10235 cystine transporter subunit low > 104
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.75 EX31_RS09435 cystine ABC transporter substrate-binding protein low > 89
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.57 Pf6N2E2_3919 Cystine ABC transporter, periplasmic cystine-binding protein FliY low > 103
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.56 PP_0227 periplasmic cystine-binding protein low > 96
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.60 PfGW456L13_444 Cystine ABC transporter, periplasmic cystine-binding protein FliY low > 87
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.61 OH686_18905 L-cystine ABC transporter (wide substrate range), substrate-binding protein FliY low > 80
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.58 AO353_11675 cystine transporter subunit low > 101
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.55 PFLU_RS01215 cystine ABC transporter substrate-binding protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.55 PFLU_RS01215 cystine ABC transporter substrate-binding protein low > 109
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.58 Pf1N1B4_1693 Cystine ABC transporter, periplasmic cystine-binding protein FliY low > 87
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.55 PS417_01105 cystine transporter subunit low > 88
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.29 QEN71_RS05410 amino acid ABC transporter substrate-binding protein low > 153
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.36 H281DRAFT_00742 amino acid ABC transporter substrate-binding protein, PAAT family low > 103
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.60 Psyr_0358 Diaminopimelate-binding protein / L-cystine-binding protein low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.60 Psyr_0358 Diaminopimelate-binding protein / L-cystine-binding protein low > 86
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.37 BPHYT_RS08560 cysteine ABC transporter substrate-binding protein low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.36 ABIE53_001953 cystine transport system substrate-binding protein low > 113
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.26 ABCV34_RS15125 amino acid ABC transporter substrate-binding protein low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.20 GFF5700 extracellular solute-binding protein, family 3 low > 90
Variovorax sp. OAS795 0.53 ABID97_RS20855 efflux RND transporter permease subunit 0.21 ABID97_RS20045 transporter substrate-binding domain-containing protein
Azospirillum sp. SherDot2 0.53 MPMX19_05477 Multidrug resistance protein MdtB 0.30 MPMX19_05074 L-cystine-binding protein TcyA low > 112
Magnetospirillum magneticum AMB-1 0.52 AMB_RS17370 acriflavine resistance protein B 0.12 AMB_RS11580 amino acid ABC transporter substrate-binding protein low > 64
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4792.1 Acriflavin resistance protein 0.13 Xcc-8004.797.1 Cyclohexadienyl dehydratase (EC 4.2.1.51)(EC 4.2.1.91) low > 74

Not shown: 14 genomes with orthologs for NOLOHH_15540 only; 6 genomes with orthologs for NOLOHH_16410 only