Conservation of cofitness between Psest_2037 and Psest_2863 in Pseudomonas stutzeri RCH2

51 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas stutzeri RCH2 1.0 Psest_2037 uroporphyrin-III C-methyltransferase 1.0 Psest_2863 Transcriptional regulator 0.49 2
Pseudomonas fluorescens FW300-N1B4 0.81 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.82 Pf1N1B4_3152 LysR family transcriptional regulator PA3398 0.52 69
Pseudomonas fluorescens FW300-N2E2 0.81 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.82 Pf6N2E2_2984 LysR family transcriptional regulator PA3398 low > 103
Pseudomonas sp. RS175 0.81 PFR28_02603 Siroheme synthase 0.83 PFR28_00480 HTH-type transcriptional activator CmpR 0.37 63
Pseudomonas fluorescens FW300-N2C3 0.81 AO356_22200 sirohydrochlorin ferrochelatase 0.82 AO356_05630 LysR family transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N2E3 0.80 AO353_27625 sirohydrochlorin ferrochelatase 0.82 AO353_16845 LysR family transcriptional regulator — —
Pseudomonas syringae pv. syringae B728a 0.80 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase 0.82 Psyr_1386 transcriptional regulator, LysR family low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.80 Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase 0.82 Psyr_1386 transcriptional regulator, LysR family low > 86
Pseudomonas fluorescens SBW25-INTG 0.80 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.82 PFLU_RS05920 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.80 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase 0.82 PFLU_RS05920 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens GW456-L13 0.80 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.77 PfGW456L13_4660 LysR family transcriptional regulator PA3398 low > 87
Pseudomonas simiae WCS417 0.79 PS417_16465 sirohydrochlorin ferrochelatase 0.82 PS417_05850 LysR family transcriptional regulator low > 88
Pseudomonas sp. S08-1 0.76 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase 0.84 OH686_18820 Transcriptional regulator, LysR family low > 80
Pseudomonas putida KT2440 0.75 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase 0.81 PP_1637 Transcriptional regulator, LysR family low > 96
Acinetobacter radioresistens SK82 0.54 MPMX26_00706 Siroheme synthase 0.37 MPMX26_02541 HTH-type transcriptional regulator CysL — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.51 OHPLBJKB_00334 Siroheme synthase 0.37 OHPLBJKB_01554 HTH-type transcriptional regulator CysL low > 73
Escherichia coli BW25113 0.51 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) 0.37 b2157 yeiE predicted DNA-binding transcriptional regulator (NCBI) low > 76
Escherichia coli BL21 0.51 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase 0.37 ECD_02086 putative DNA-binding transcriptional regulator low > 60
Escherichia coli ECOR27 0.51 NOLOHH_08980 cysG siroheme synthase CysG 0.33 NOLOHH_15070 yieE DNA-binding transcriptional regulator YeiE low > 57
Escherichia coli ECRC62 0.51 BNILDI_02540 cysG siroheme synthase CysG 0.37 BNILDI_13990 yieE DNA-binding transcriptional regulator YeiE — —
Escherichia coli ECRC102 0.51 NIAGMN_14950 cysG siroheme synthase CysG 0.37 NIAGMN_21260 yieE DNA-binding transcriptional regulator YeiE — —
Escherichia coli ECRC98 0.51 JDDGAC_20810 cysG siroheme synthase CysG 0.37 JDDGAC_27455 yieE DNA-binding transcriptional regulator YeiE — —
Escherichia coli Nissle 1917 0.51 ECOLIN_RS19285 siroheme synthase CysG 0.37 ECOLIN_RS12630 DNA-binding transcriptional regulator YeiE low > 52
Escherichia coli ECRC101 0.51 MCAODC_07710 cysG siroheme synthase CysG 0.37 MCAODC_14545 yieE DNA-binding transcriptional regulator YeiE — —
Escherichia coli ECRC99 0.51 KEDOAH_10960 cysG siroheme synthase CysG 0.37 KEDOAH_04690 yieE DNA-binding transcriptional regulator YeiE — —
Escherichia fergusonii Becca 0.51 EFB2_00454 Siroheme synthase 0.33 EFB2_01699 HTH-type transcriptional regulator CysL low > 86
Escherichia coli ECRC101 0.51 OKFHMN_17180 cysG siroheme synthase CysG 0.37 OKFHMN_23495 yieE DNA-binding transcriptional regulator YeiE — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) 0.36 GFF3777 LysR family transcriptional regulator YeiE low > 78
Escherichia coli ECOR38 0.50 HEPCGN_16010 cysG siroheme synthase CysG 0.37 HEPCGN_22760 yieE DNA-binding transcriptional regulator YeiE low > 85
Klebsiella michiganensis M5al 0.50 BWI76_RS26055 siroheme synthase 0.36 BWI76_RS19690 LysR family transcriptional regulator 0.56 80
Enterobacter asburiae PDN3 0.50 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase 0.35 EX28DRAFT_0399 Transcriptional regulator low > 76
Enterobacter sp. TBS_079 0.50 MPMX20_04271 Siroheme synthase 0.35 MPMX20_03128 HTH-type transcriptional activator CmpR 0.36 18
Pectobacterium carotovorum WPP14 0.49 HER17_RS04280 siroheme synthase CysG 0.41 HER17_RS12840 LysR family transcriptional regulator low > 75
Pantoea sp. MT58 0.49 IAI47_04175 uroporphyrinogen-III C-methyltransferase 0.36 IAI47_06680 LysR family transcriptional regulator low > 76
Rahnella sp. WP5 0.49 EX31_RS07885 uroporphyrinogen-III C-methyltransferase 0.42 EX31_RS19050 LysR family transcriptional regulator low > 89
Serratia liquefaciens MT49 0.48 IAI46_03710 uroporphyrinogen-III C-methyltransferase 0.38 IAI46_17215 LysR family transcriptional regulator low > 86
Erwinia tracheiphila SCR3 0.48 LU632_RS06420 cysG siroheme synthase CysG 0.36 LU632_RS17295 LysR family transcriptional regulator low > 74
Dickeya dianthicola 67-19 0.47 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase 0.39 HGI48_RS09285 LysR family transcriptional regulator low > 71
Dickeya dianthicola ME23 0.47 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase 0.39 DZA65_RS09590 LysR family transcriptional regulator low > 75
Dickeya dadantii 3937 0.46 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase 0.39 DDA3937_RS09260 LysR family transcriptional regulator low > 74
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS05880 siroheme synthase CysG 0.36 ABZR86_RS19780 LysR family transcriptional regulator low > 74
Castellaniella sp019104865 MT123 0.40 ABCV34_RS00210 siroheme synthase CysG 0.33 ABCV34_RS05920 LysR substrate-binding domain-containing protein low > 48
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_05980 cysG siroheme synthase CysG 0.35 OKGIIK_02230 lysR LysR family transcriptional regulator low > 52
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS00910 siroheme synthase CysG 0.35 LRK54_RS12835 LysR family transcriptional regulator low > 59
Brevundimonas sp. GW460-12-10-14-LB2 0.37 A4249_RS09675 siroheme synthase CysG 0.24 A4249_RS01115 LysR substrate-binding domain-containing protein low > 48
Rhodanobacter denitrificans MT42 0.36 LRK55_RS00685 siroheme synthase CysG 0.35 LRK55_RS12535 LysR family transcriptional regulator low > 63
Agrobacterium fabrum C58 0.34 Atu3899 siroheme synthase 0.24 Atu0672 transcriptional regulator, LysR family low > 89
Rhodopseudomonas palustris CGA009 0.34 TX73_021850 siroheme synthase CysG 0.25 TX73_009100 LysR family transcriptional regulator low > 86
Rhizobium sp. OAE497 0.33 ABIE40_RS09140 siroheme synthase CysG 0.22 ABIE40_RS15535 LysR family transcriptional regulator low > 107
Dinoroseobacter shibae DFL-12 0.29 Dshi_1155 uroporphyrin-III C-methyltransferase (RefSeq) 0.12 Dshi_1431 transcriptional regulator, LysR family (RefSeq) — —
Rhodospirillum rubrum S1H 0.29 Rru_A1933 Uroporphyrin-III C-methyltransferase (NCBI) 0.21 Rru_A0606 Transcriptional Regulator, LysR family (NCBI) — —
Mycobacterium tuberculosis H37Rv 0.19 Rv2847c Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase 0.13 Rv2282c Probable transcription regulator (LysR family) — —

Not shown: 5 genomes with orthologs for Psest_2037 only; 32 genomes with orthologs for Psest_2863 only