Conservation of cofitness between GFF1982 and GFF1895 in Hydrogenophaga sp. GW460-11-11-14-LB1

34 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF1982 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) 1.0 GFF1895 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.68 1
Variovorax sp. OAS795 0.69 ABID97_RS03315 flavin reductase family protein 0.82 ABID97_RS19485 CoA-acylating methylmalonate-semialdehyde dehydrogenase — —
Variovorax sp. SCN45 0.68 GFF3472 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) 0.81 GFF5041 Malonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.18) low > 127
Acidovorax sp. GW101-3H11 0.65 Ac3H11_4854 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) 0.53 Ac3H11_4340 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) low > 79
Paraburkholderia bryophila 376MFSha3.1 0.53 H281DRAFT_04140 NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family 0.70 H281DRAFT_03264 methylmalonate-semialdehyde dehydrogenase [acylating] low > 103
Herbaspirillum seropedicae SmR1 0.53 HSERO_RS03385 flavin reductase 0.67 HSERO_RS24005 methylmalonate-semialdehyde dehydrogenase low > 78
Paraburkholderia graminis OAS925 0.53 ABIE53_003377 flavin reductase (DIM6/NTAB) family NADH-FMN oxidoreductase RutF 0.70 ABIE53_005233 malonate-semialdehyde dehydrogenase (acetylating)/methylmalonate-semialdehyde dehydrogenase low > 113
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS16015 flavin reductase 0.69 BPHYT_RS28825 methylmalonate-semialdehyde dehydrogenase low > 109
Paraburkholderia sabiae LMG 24235 0.52 QEN71_RS02690 flavin reductase family protein 0.75 QEN71_RS37655 CoA-acylating methylmalonate-semialdehyde dehydrogenase low > 153
Cupriavidus basilensis FW507-4G11 0.50 RR42_RS15365 flavin reductase 0.72 RR42_RS34225 methylmalonate-semialdehyde dehydrogenase low > 128
Ralstonia solanacearum PSI07 0.49 RPSI07_RS20165 flavin reductase 0.68 RPSI07_RS04870 methylmalonate-semialdehyde dehydrogenase (CoA acylating) low > 81
Ralstonia solanacearum UW163 0.49 UW163_RS00505 flavin reductase 0.68 UW163_RS20405 methylmalonate-semialdehyde dehydrogenase (CoA acylating) — —
Ralstonia solanacearum IBSBF1503 0.49 RALBFv3_RS13060 flavin reductase 0.68 RALBFv3_RS18725 methylmalonate-semialdehyde dehydrogenase (CoA acylating) low > 76
Ralstonia solanacearum GMI1000 0.48 RS_RS03845 flavin reductase 0.70 RS_RS12715 methylmalonate-semialdehyde dehydrogenase (CoA acylating) low > 80
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_2735 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-) 0.57 PfGW456L13_2 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) low > 87
Ralstonia sp. UNC404CL21Col 0.47 ABZR87_RS09130 flavin reductase family protein 0.67 ABZR87_RS19665 CoA-acylating methylmalonate-semialdehyde dehydrogenase low > 80
Castellaniella sp019104865 MT123 0.38 ABCV34_RS00650 flavin reductase family protein 0.71 ABCV34_RS07430 CoA-acylating methylmalonate-semialdehyde dehydrogenase low > 48
Azospirillum sp. SherDot2 0.37 MPMX19_01350 p-hydroxyphenylacetate 3-hydroxylase, reductase component 0.62 MPMX19_04040 Putative 3-oxopropanoate dehydrogenase — —
Pseudomonas simiae WCS417 0.37 PS417_17920 nitrilotriacetate monooxygenase 0.72 PS417_10925 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) low > 88
Azospirillum brasilense Sp245 0.36 AZOBR_RS20045 flavin reductase 0.55 AZOBR_RS22500 methylmalonate-semialdehyde dehydrogenase low > 97
Caulobacter crescentus NA1000 0.32 CCNA_02358 FMN reductase 0.52 CCNA_01360 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) (from data) low > 66
Caulobacter crescentus NA1000 Δfur 0.32 CCNA_02358 FMN reductase 0.52 CCNA_01360 malonate-semialdehyde dehydrogenase IolA low > 67
Pseudomonas putida KT2440 0.29 PP_3643 putative Oxidoreductase 0.58 PP_0597 methylmalonate-semialdehyde dehydrogenase low > 96
Dinoroseobacter shibae DFL-12 0.29 Dshi_2755 flavin reductase domain protein FMN-binding (RefSeq) 0.49 Dshi_1747 methylmalonate-semialdehyde dehydrogenase (RefSeq) low > 64
Rhodospirillum rubrum S1H 0.28 Rru_A1841 Flavin reductase-like, FMN-binding (NCBI) 0.54 Rru_A1542 Methylmalonate-semialdehyde dehydrogenase (NCBI) low > 58
Mycobacterium tuberculosis H37Rv 0.28 Rv3567c Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase. 0.55 Rv0753c Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) low > 58
Pseudomonas syringae pv. syringae B728a ΔmexB 0.27 Psyr_2406 Flavin reductase-like protein 0.63 Psyr_3271 methylmalonate-semialdehyde dehydrogenase (acylating) low > 86
Pseudomonas syringae pv. syringae B728a 0.27 Psyr_2406 Flavin reductase-like protein 0.63 Psyr_3271 methylmalonate-semialdehyde dehydrogenase (acylating) low > 86
Sphingomonas koreensis DSMZ 15582 0.25 Ga0059261_2931 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family 0.56 Ga0059261_3677 methylmalonic acid semialdehyde dehydrogenase low > 68
Rhodopseudomonas palustris CGA009 0.23 TX73_013510 flavin reductase family protein 0.57 TX73_017860 CoA-acylating methylmalonate-semialdehyde dehydrogenase low > 86
Enterobacter sp. TBS_079 0.20 MPMX20_01694 FMN reductase (NADH) RutF 0.55 MPMX20_03375 Putative 3-oxopropanoate dehydrogenase low > 85
Klebsiella michiganensis M5al 0.20 BWI76_RS10755 pyrimidine utilization flavin reductase protein F 0.51 BWI76_RS03070 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) (from data) low > 92
Serratia liquefaciens MT49 0.19 IAI46_09030 pyrimidine utilization flavin reductase protein F 0.53 IAI46_02640 CoA-acylating methylmalonate-semialdehyde dehydrogenase low > 86
Alteromonas macleodii MIT1002 0.19 MIT1002_03463 FMN reductase (NADH) RutF 0.54 MIT1002_03462 Methylmalonate-semialdehyde dehydrogenase [acylating] low > 70
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.15 GFF3275 4-hydroxyphenylacetate 3-monooxygenase, reductase component (EC 1.6.8.-) 0.54 GFF888 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) low > 78

Not shown: 2 genomes with orthologs for GFF1982 only; 29 genomes with orthologs for GFF1895 only