Conservation of cofitness between EX28DRAFT_3669 and EX28DRAFT_0537 in Enterobacter asburiae PDN3

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Enterobacter asburiae PDN3 1.0 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 1.0 EX28DRAFT_0537 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.93 4
Enterobacter sp. TBS_079 0.99 MPMX20_00768 3-isopropylmalate dehydrogenase 0.97 MPMX20_03004 Histidine biosynthesis bifunctional protein HisB 0.92 20
Klebsiella michiganensis M5al 0.95 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.86 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.87 31
Klebsiella pneumoniae MKP103 0.95 KDGMDA_12905 3-isopropylmalate dehydrogenase 0.86 KDGMDA_26105 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 95
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.92 GFF3910 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) low > 78
Escherichia fergusonii Becca 0.94 EFB2_03972 3-isopropylmalate dehydrogenase 0.91 EFB2_01834 Histidine biosynthesis bifunctional protein HisB low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.91 ECOLIN_RS11955 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECOR38 0.94 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.92 HEPCGN_03210 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 14
Escherichia coli ECRC99 0.94 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase 0.92 KEDOAH_03645 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Escherichia coli ECRC98 0.94 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.92 JDDGAC_28615 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.79 47
Escherichia coli ECRC102 0.94 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.92 NIAGMN_22450 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.97 36
Escherichia coli ECRC101 0.94 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.92 MCAODC_20435 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.85 26
Escherichia coli ECRC100 0.94 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.92 OKFHMN_24505 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 42
Escherichia coli ECRC62 0.93 BNILDI_08545 leuA 2-isopropylmalate synthase 0.91 BNILDI_14730 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.90 66
Escherichia coli BW25113 0.93 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.92 b2022 hisB imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) 0.96 8
Escherichia coli BL21 0.93 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.92 ECD_01924 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase 0.92 22
Escherichia coli HS(pFamp)R (ATCC 700891) 0.93 OHPLBJKB_03584 3-isopropylmalate dehydrogenase 0.92 OHPLBJKB_01678 Histidine biosynthesis bifunctional protein HisB low > 74
Escherichia coli ECOR27 0.93 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.92 NOLOHH_15820 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 48
Dickeya dianthicola 67-19 0.88 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.83 HGI48_RS09735 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 71
Dickeya dadantii 3937 0.88 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.83 DDA3937_RS09725 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.72 27
Pectobacterium carotovorum WPP14 0.87 HER17_RS03080 3-isopropylmalate dehydrogenase 0.82 HER17_RS12240 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 16
Dickeya dianthicola ME23 0.87 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.83 DZA65_RS10045 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.72 36
Rahnella sp. WP5 0.87 EX31_RS03685 3-isopropylmalate dehydrogenase 0.83 EX31_RS11450 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.96 36
Serratia liquefaciens MT49 0.87 IAI46_03350 3-isopropylmalate dehydrogenase 0.82 IAI46_08200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 86
Erwinia amylovora T8 0.85 OLJFJH_01290 3-isopropylmalate dehydrogenase 0.84 OLJFJH_12170 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.88 35
Erwinia tracheiphila HP pepo 2.2 0.82 IJEDHG_06000 leuB 3-isopropylmalate dehydrogenase 0.83 IJEDHG_19080 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.81 33
Erwinia tracheiphila SCR3 0.82 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.83 LU632_RS08935 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.81 21
Pantoea agglomerans CFBP13505 P0401 0.82 PagCFBP13505_RS12995 3-isopropylmalate dehydrogenase 0.83 PagCFBP13505_RS01200 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 74
Pantoea sp. MT58 0.82 IAI47_16005 3-isopropylmalate dehydrogenase 0.83 IAI47_07080 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.97 14
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_12600 3-isopropylmalate dehydrogenase 0.68 CSW01_05760 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase low > 62
Shewanella oneidensis MR-1 0.70 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.62 SO2071 hisB imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) 0.98 16
Shewanella sp. ANA-3 0.70 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.62 Shewana3_1851 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.95 7
Shewanella loihica PV-4 0.69 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.65 Shew_2200 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.99 3
Shewanella amazonensis SB2B 0.69 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.62 Sama_1944 imidazole glycerol-phosphate dehydratase/histidinol phosphatase (RefSeq) 0.94 30
Alteromonas macleodii MIT1002 0.63 MIT1002_00948 3-isopropylmalate dehydrogenase 0.67 MIT1002_02635 Histidine biosynthesis bifunctional protein HisB 0.95 39
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.53 Xcc-8004.2946.1 Histidinol-phosphatase (EC 3.1.3.15) / Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) 0.93 8
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.46 HMPREF1058_RS15885 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.83 10
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.45 ABI39_RS11845 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.79 27
Pontibacter actiniarum KMM 6156, DSM 19842 0.44 CA264_09445 3-isopropylmalate dehydrogenase 0.46 CA264_05040 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase low > 74
Bacteroides thetaiotaomicron VPI-5482 0.43 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.46 BT0203 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) 0.83 34
Bacteroides ovatus ATCC 8483 0.43 BACOVA_04600 3-isopropylmalate dehydrogenase 0.46 BACOVA_01232 histidinol-phosphatase 0.91 28
Echinicola vietnamensis KMM 6221, DSM 17526 0.42 Echvi_2062 3-isopropylmalate dehydrogenase 0.45 Echvi_2457 histidinol-phosphatase — —
Pedobacter sp. GW460-11-11-14-LB5 0.42 CA265_RS15850 3-isopropylmalate dehydrogenase 0.43 CA265_RS03625 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.92 22
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.46 HMPREF1078_RS02440 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.93 11
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.47 HMPREF1181_RS04850 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.89 25
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS11605 3-isopropylmalate dehydrogenase 0.44 ABZR88_RS06870 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB — —
Lysobacter sp. OAE881 0.41 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.54 ABIE51_RS13315 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 62
Rhodanobacter sp000427505 FW510-R12 0.41 LRK53_RS03100 3-isopropylmalate dehydrogenase 0.52 LRK53_RS08470 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 59
Rhodanobacter denitrificans MT42 0.40 LRK55_RS09965 3-isopropylmalate dehydrogenase 0.53 LRK55_RS01375 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 63
Cellulophaga baltica 18 0.40 M666_RS15045 3-isopropylmalate dehydrogenase 0.45 M666_RS17145 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 67
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.53 LRK54_RS01595 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.58 55
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.52 OKGIIK_04960 hisB bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB low > 53
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.53 ABZR86_RS06720 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB 0.92 45

Not shown: 67 genomes with orthologs for EX28DRAFT_3669 only; 0 genomes with orthologs for EX28DRAFT_0537 only