Conservation of cofitness between ECD_00877 and ECD_03499 in Escherichia coli BL21

51 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00877 HCP oxidoreductase, NADH-dependent 1.0 ECD_03499 orotate phosphoribosyltransferase low > 61
Escherichia coli ECRC62 1.00 BNILDI_20490 hcr NADH oxidoreductase 1.00 BNILDI_04035 pyrE Orotate phosphoribosyltransferase low > 75
Escherichia coli ECOR27 1.00 NOLOHH_22235 hcr NADH oxidoreductase 0.99 NOLOHH_07480 pyrE Orotate phosphoribosyltransferase low > 75
Escherichia coli BW25113 1.00 b0872 hcr HCP oxidoreductase, NADH-dependent (NCBI) 1.00 b3642 pyrE orotate phosphoribosyltransferase (NCBI) low > 76
Escherichia fergusonii Becca 0.99 EFB2_03189 NADH oxidoreductase HCR 1.00 EFB2_00171 Orotate phosphoribosyltransferase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04640 NADH oxidoreductase 1.00 ECOLIN_RS20750 orotate phosphoribosyltransferase low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_02796 NADH oxidoreductase HCR 1.00 OHPLBJKB_00060 Orotate phosphoribosyltransferase low > 73
Escherichia coli ECOR38 0.99 HEPCGN_02175 hcr NADH oxidoreductase 1.00 HEPCGN_14420 pyrE Orotate phosphoribosyltransferase low > 87
Escherichia coli ECRC99 0.99 KEDOAH_22070 hcr NADH oxidoreductase 0.99 KEDOAH_12550 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC100 0.99 OKFHMN_05840 hcr NADH oxidoreductase 0.99 OKFHMN_15600 pyrE Orotate phosphoribosyltransferase low > 80
Escherichia coli ECRC98 0.99 JDDGAC_09475 hcr NADH oxidoreductase 0.99 JDDGAC_19225 pyrE Orotate phosphoribosyltransferase low > 86
Escherichia coli ECRC102 0.99 NIAGMN_03880 hcr NADH oxidoreductase 0.99 NIAGMN_13360 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC101 0.99 MCAODC_25055 hcr NADH oxidoreductase 0.99 MCAODC_06110 pyrE Orotate phosphoribosyltransferase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF4910 NADH oxidoreductase hcr (EC 1.-.-.-) 0.97 GFF367 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 78
Enterobacter sp. TBS_079 0.91 MPMX20_01534 NADH oxidoreductase HCR 0.94 MPMX20_00093 Orotate phosphoribosyltransferase low > 85
Klebsiella michiganensis M5al 0.91 BWI76_RS09565 hybrid-cluster NAD(P)-dependent oxidoreductase 0.96 BWI76_RS27385 orotate phosphoribosyltransferase low > 92
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2060 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.96 EX28DRAFT_3892 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pectobacterium carotovorum WPP14 0.62 HER17_RS12430 NADH oxidoreductase 0.90 HER17_RS20850 orotate phosphoribosyltransferase low > 75
Serratia liquefaciens MT49 0.59 IAI46_08470 NADH oxidoreductase 0.91 IAI46_24845 orotate phosphoribosyltransferase low > 86
Dickeya dadantii 3937 0.59 DDA3937_RS09535 NADH oxidoreductase 0.90 DDA3937_RS20535 orotate phosphoribosyltransferase low > 74
Dickeya dianthicola ME23 0.57 DZA65_RS09860 NADH oxidoreductase 0.88 DZA65_RS00735 orotate phosphoribosyltransferase low > 75
Dickeya dianthicola 67-19 0.57 HGI48_RS09550 NADH oxidoreductase 0.88 HGI48_RS00680 orotate phosphoribosyltransferase low > 71
Rahnella sp. WP5 0.53 EX31_RS18595 NADH oxidoreductase 0.90 EX31_RS14500 orotate phosphoribosyltransferase low > 89
Shewanella sp. ANA-3 0.27 Shewana3_3010 oxidoreductase FAD-binding subunit (RefSeq) 0.82 Shewana3_3776 pyrE orotate phosphoribosyltransferase (RefSeq) low > 73
Shewanella loihica PV-4 0.27 Shew_1070 oxidoreductase FAD-binding subunit (RefSeq) 0.83 Shew_3487 pyrE orotate phosphoribosyltransferase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.27 SO1364 iron-sulfur cluster-binding protein (NCBI ptt file) 0.82 SO4255 pyrE orotate phosphoribosyltransferase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.26 Sama_0896 iron-sulfur cluster-binding protein (RefSeq) 0.84 Sama_0321 pyrE orotate phosphoribosyltransferase (RefSeq) low > 62
Ralstonia solanacearum GMI1000 0.23 RS_RS17500 hybrid-cluster NAD(P)-dependent oxidoreductase 0.52 RS_RS00685 orotate phosphoribosyltransferase — —
Pseudomonas simiae WCS417 0.22 PS417_26215 ferredoxin 0.68 PS417_27795 orotate phosphoribosyltransferase low > 88
Pseudomonas fluorescens SBW25-INTG 0.22 PFLU_RS27860 glycine-betaine demethylase subunit GbcB 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25 0.22 PFLU_RS27860 glycine-betaine demethylase subunit GbcB 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens GW456-L13 0.21 PfGW456L13_1112 GbcB Glycine betaine demethylase subunit B 0.67 PfGW456L13_788 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens FW300-N2C3 0.21 AO356_00630 ferredoxin 0.67 AO356_12520 orotate phosphoribosyltransferase low > 104
Pseudomonas sp. RS175 0.21 PFR28_04139 3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component 0.71 PFR28_04417 Orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.21 Psyr_4775 Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.21 Psyr_4775 Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.21 Pf6N2E2_4714 GbcB Glycine betaine demethylase subunit B 0.68 Pf6N2E2_4370 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas fluorescens FW300-N2E3 0.21 AO353_07675 ferredoxin 0.67 AO353_09245 orotate phosphoribosyltransferase — —
Pseudomonas putida KT2440 0.21 PP_0316 putative glycine-betaine dioxygenase subunit 0.67 PP_5291 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.21 Pf1N1B4_2448 GbcB Glycine betaine demethylase subunit B 0.67 Pf1N1B4_2120 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas sp. S08-1 0.19 OH686_04175 Flavodoxin (ferredoxin-NADPH reductases) family 1 0.69 OH686_13590 Orotate phosphoribosyltransferase low > 80
Cupriavidus basilensis FW507-4G11 0.16 RR42_RS23745 phenylacetic acid degradation protein 0.55 RR42_RS01225 orotate phosphoribosyltransferase — —
Acinetobacter radioresistens SK82 0.15 MPMX26_01556 1,2-phenylacetyl-CoA epoxidase, subunit E 0.56 MPMX26_02937 Orotate phosphoribosyltransferase — —
Herbaspirillum seropedicae SmR1 0.15 HSERO_RS20630 phenylacetic acid degradation protein 0.55 HSERO_RS23380 orotate phosphoribosyltransferase — —
Marinobacter adhaerens HP15 0.15 HP15_2701 phenylacetic acid degradation oxidoreductase PaaK 0.64 HP15_298 orotate phosphoribosyltransferase low > 73
Variovorax sp. SCN45 0.14 GFF6097 1,2-phenylacetyl-CoA epoxidase, subunit E (EC 1.14.13.149) 0.49 GFF5065 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 127
Ralstonia solanacearum PSI07 0.14 RPSI07_RS02150 phenylacetate-CoA oxygenase/reductase subunit PaaK 0.52 RPSI07_RS23295 orotate phosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.14 RALBFv3_RS20640 phenylacetate-CoA oxygenase/reductase subunit PaaK 0.53 RALBFv3_RS10075 orotate phosphoribosyltransferase — —
Ralstonia solanacearum UW163 0.14 UW163_RS18535 phenylacetate-CoA oxygenase/reductase subunit PaaK 0.53 UW163_RS03505 orotate phosphoribosyltransferase — —
Variovorax sp. OAS795 0.13 ABID97_RS22805 1,2-phenylacetyl-CoA epoxidase subunit PaaE 0.48 ABID97_RS03910 orotate phosphoribosyltransferase low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.13 GFF1689 Phenylacetate-CoA oxygenase/reductase, PaaK subunit 0.49 GFF1882 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 90
Xanthomonas campestris pv. campestris strain 8004 0.11 Xcc-8004.4922.1 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 0.47 Xcc-8004.4884.1 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 74

Not shown: 13 genomes with orthologs for ECD_00877 only; 19 genomes with orthologs for ECD_03499 only