Conservation of cofitness between CSW01_12845 and CSW01_10660 in Vibrio cholerae E7946 ATCC 55056

44 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12845 metalloprotease PmbA 1.0 CSW01_10660 sigma-54-dependent Fis family transcriptional regulator 0.85 19
Serratia liquefaciens MT49 0.65 IAI46_22575 metalloprotease PmbA 0.31 IAI46_19460 two-component system response regulator GlrR low > 86
Escherichia coli ECRC101 0.64 MCAODC_02430 pmbA metalloprotease PmbA 0.30 MCAODC_12025 qseF two-component system response regulator QseF/GlrR low > 88
Escherichia coli ECRC100 0.64 OKFHMN_11925 pmbA metalloprotease PmbA 0.30 OKFHMN_21495 qseF two-component system response regulator QseF/GlrR low > 79
Escherichia coli ECRC98 0.64 JDDGAC_15565 pmbA metalloprotease PmbA 0.30 JDDGAC_25160 qseF two-component system response regulator QseF/GlrR low > 87
Escherichia coli ECRC102 0.64 NIAGMN_09775 pmbA metalloprotease PmbA 0.30 NIAGMN_19265 qseF two-component system response regulator QseF/GlrR low > 80
Escherichia coli ECRC62 0.64 BNILDI_07325 pmbA metalloprotease PmbA 0.30 BNILDI_11970 qseF two-component system response regulator QseF/GlrR low > 75
Escherichia coli ECRC99 0.64 KEDOAH_16230 pmbA metalloprotease PmbA 0.30 KEDOAH_06725 qseF two-component system response regulator QseF/GlrR
Enterobacter asburiae PDN3 0.64 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs 0.30 EX28DRAFT_0096 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains low > 76
Enterobacter sp. TBS_079 0.64 MPMX20_00517 Metalloprotease PmbA 0.30 MPMX20_03423 Transcriptional regulatory protein QseF low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.64 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.31 GFF2455 Putative sensory histidine kinase YfhA low > 78
Klebsiella michiganensis M5al 0.64 BWI76_RS02850 metalloprotease PmbA 0.31 BWI76_RS21250 two-component system response regulator GlrR low > 92
Shewanella oneidensis MR-1 0.58 SO4078 pmbA pmba protein (NCBI ptt file) 0.58 SO3230 flrC flagellar regulatory protein C (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.58 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.58 Shewana3_1340 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) low > 73
Shewanella amazonensis SB2B 0.58 Sama_0482 PmbA protein (RefSeq) 0.58 Sama_2299 response regulator receiver protein (RefSeq) low > 62
Shewanella loihica PV-4 0.56 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.58 Shew_1364 two component, sigma54 specific, Fis family transcriptional regulator (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.54 MIT1002_00230 peptidase PmbA 0.61 MIT1002_01083 Transcriptional regulatory protein ZraR low > 70
Pseudomonas putida KT2440 0.49 PP_0942 regulatory protease 0.48 PP_4371 two component system AtoC DNA-binding transcriptional activator low > 96
Pseudomonas sp. BP01 0.48 JOY50_RS11080 pmbA metalloprotease PmbA 0.49 JOY50_RS00695 sigma-54 dependent transcriptional regulator low > 84
Pseudomonas sp. RS175 0.48 PFR28_00163 Metalloprotease PmbA 0.50 PFR28_00830 Regulatory protein AtoC low > 88
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_07085 peptidase PmbA 0.48 AO356_03845 Fis family transcriptional regulator low > 104
Pseudomonas lactucae CFBP13502 0.48 GEMAOFIL_01064 Metalloprotease PmbA 0.49 GEMAOFIL_04161 Regulatory protein AtoC low > 93
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS04350 metalloprotease PmbA 0.49 PFLU_RS21785 sigma-54-dependent Fis family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.48 PFLU_RS04350 metalloprotease PmbA 0.49 PFLU_RS21785 sigma-54-dependent Fis family transcriptional regulator low > 109
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.50 Pf6N2E2_2595 Flagellar regulatory protein FleQ low > 103
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_05205 peptidase PmbA 0.50 AO353_18670 Fis family transcriptional regulator 0.30 67
Pseudomonas sp. DMC3 0.47 GFF1818 Metalloprotease PmbA 0.50 GFF2447 Regulatory protein AtoC low > 89
Pseudomonas simiae WCS417 0.47 PS417_04295 peptidase PmbA 0.49 PS417_19815 Fis family transcriptional regulator
Pseudomonas sp. SVBP6 0.47 COO64_RS04235 pmbA metalloprotease PmbA 0.48 COO64_RS21290 sigma-54 dependent transcriptional regulator low > 93
Pseudomonas syringae pv. syringae B728a 0.47 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.48 Psyr_3459 Helix-turn-helix, Fis-type low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.47 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.48 Psyr_3459 Helix-turn-helix, Fis-type low > 86
Pseudomonas sp. S08-1 0.47 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex 0.51 OH686_02845 Flagellar two-component response regulator FleR low > 80
Pseudomonas aeruginosa PA14 0.47 IKLFDK_01720 metalloprotease PmbA 0.49 IKLFDK_05055 sigma-54-dependent response regulator transcription factor FleR low > 100
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex 0.49 PfGW456L13_4355 Flagellar regulatory protein FleQ low > 87
Pseudomonas stutzeri RCH2 0.46 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.50 Psest_1767 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains low > 67
Pseudomonas segetis P6 0.46 MPMX49_03863 Metalloprotease PmbA 0.51 MPMX49_03148 Regulatory protein AtoC low > 75
Dechlorosoma suillum PS 0.44 Dsui_1234 putative Zn-dependent protease-like protein 0.45 Dsui_1758 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains low > 51
Azospirillum brasilense Sp245 0.32 AZOBR_RS11930 modulator protein 0.30 AZOBR_RS20165 ATPase AAA low > 97
Rhodopseudomonas palustris CGA009 0.28 TX73_005930 TldD/PmbA family protein 0.30 TX73_006510 sigma-54 dependent transcriptional regulator 0.30 59
Caulobacter crescentus NA1000 Δfur 0.28 CCNA_00311 Zn-dependent protease family protein 0.31 CCNA_00954 AAA-family response regulator flbD low > 67
Caulobacter crescentus NA1000 0.28 CCNA_00311 Zn-dependent protease family protein 0.31 CCNA_00954 AAA-family response regulator flbD 0.71 27
Magnetospirillum magneticum AMB-1 0.27 AMB_RS22120 TldD/PmbA family protein 0.32 AMB_RS02570 sigma-54-dependent Fis family transcriptional regulator low > 64
Rhodospirillum rubrum S1H 0.25 Rru_A0575 Peptidase U62, modulator of DNA gyrase (NCBI) 0.31 Rru_A0540 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.25 A4249_RS09195 TldD/PmbA family protein 0.30 A4249_RS09765 sigma-54 dependent transcriptional regulator low > 48
Pontibacter actiniarum KMM 6156, DSM 19842 0.06 CA264_16645 peptidase C69 0.32 CA264_09510 sigma-54-dependent Fis family transcriptional regulator low > 74

Not shown: 57 genomes with orthologs for CSW01_12845 only; 2 genomes with orthologs for CSW01_10660 only