| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_00775 | | HTH-type transcriptional repressor FabR | 1.0 | CSW01_05660 | | dethiobiotin synthase | 0.52 | 14 |
| Pantoea sp. MT58 | 0.70 | IAI47_00940 | | HTH-type transcriptional repressor FabR | 0.45 | IAI47_09755 | | ATP-dependent dethiobiotin synthetase BioD | low | > 76 |
| Pantoea agglomerans CFBP13505 P0401 | 0.70 | PagCFBP13516_RS00935 | fabR | HTH-type transcriptional repressor FabR | 0.46 | PagCFBP13516_RS09915 | bioD | dethiobiotin synthase | low | > 80 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.70 | GFF2349 | | Unsaturated fatty acid biosythesis repressor FabR, TetR family | 0.47 | GFF1784 | | Dethiobiotin synthetase (EC 6.3.3.3) | low | > 78 |
| Klebsiella michiganensis M5al | 0.70 | BWI76_RS00875 | | DNA-binding transcriptional regulator FabR | 0.46 | BWI76_RS15950 | | dethiobiotin synthase | low | > 92 |
| Pectobacterium carotovorum WPP14 | 0.70 | HER17_RS00965 | | HTH-type transcriptional repressor FabR | 0.47 | HER17_RS10730 | | dethiobiotin synthase | low | > 75 |
| Klebsiella pneumoniae MKP103 | 0.70 | KDGMDA_09390 | | HTH-type transcriptional repressor FabR | 0.47 | KDGMDA_21235 | | dethiobiotin synthase | low | > 94 |
| Klebsiella pneumoniae MRSN742743 | 0.70 | GJGHJB_04888 | fabR | HTH-type transcriptional repressor FabR | 0.47 | GJGHJB_02596 | bioD | dethiobiotin synthase | low | > 83 |
| Enterobacter asburiae PDN3 | 0.70 | EX28DRAFT_4426 | | transcriptional regulator, TetR family | 0.45 | EX28DRAFT_1492 | | dethiobiotin synthase | low | > 76 |
| Dickeya dianthicola ME23 | 0.70 | DZA65_RS21440 | | HTH-type transcriptional repressor FabR | 0.46 | DZA65_RS08980 | | ATP-dependent dethiobiotin synthetase BioD | 0.42 | 27 |
| Erwinia tracheiphila SCR3 | 0.70 | LU632_RS19580 | fabR | HTH-type transcriptional repressor FabR | 0.43 | LU632_RS12300 | bioD | dethiobiotin synthase | low | > 73 |
| Enterobacter sp. TBS_079 | 0.70 | MPMX20_04517 | | HTH-type transcriptional repressor FabR | 0.46 | MPMX20_02064 | | ATP-dependent dethiobiotin synthetase BioD 1 | low | > 85 |
| Dickeya dianthicola 67-19 | 0.70 | HGI48_RS20395 | | HTH-type transcriptional repressor FabR | 0.46 | HGI48_RS08690 | | ATP-dependent dethiobiotin synthetase BioD | low | > 71 |
| Escherichia coli BW25113 | 0.69 | b3963 | fabR | DNA-binding transcriptional repressor (RefSeq) | 0.47 | b1593 | b1593 | orf, hypothetical protein (VIMSS) | low | > 76 |
| Escherichia coli ECRC102 | 0.69 | NIAGMN_11295 | fabR | HTH-type transcriptional repressor FabR | 0.47 | NIAGMN_00330 | bioD | dethiobiotin synthase | low | > 80 |
| Escherichia coli ECOR27 | 0.69 | NOLOHH_05690 | fabR | HTH-type transcriptional repressor FabR | 0.47 | NOLOHH_18250 | bioD | dethiobiotin synthase | — | — |
| Erwinia tracheiphila HP pepo 2.2 | 0.69 | IJEDHG_13085 | fabR | HTH-type transcriptional repressor FabR | 0.43 | IJEDHG_23285 | bioD | dethiobiotin synthase | low | > 61 |
| Escherichia coli Nissle 1917 | 0.69 | ECOLIN_RS22890 | | HTH-type transcriptional repressor FabR | 0.47 | ECOLIN_RS08900 | | dethiobiotin synthase | — | — |
| Escherichia coli ECOR38 | 0.69 | HEPCGN_12200 | fabR | HTH-type transcriptional repressor FabR | 0.47 | HEPCGN_06120 | bioD | dethiobiotin synthase | low | > 88 |
| Escherichia coli ECRC100 | 0.69 | OKFHMN_13545 | fabR | HTH-type transcriptional repressor FabR | 0.47 | OKFHMN_27745 | bioD | dethiobiotin synthase | — | — |
| Serratia liquefaciens MT49 | 0.69 | IAI46_24465 | | HTH-type transcriptional repressor FabR | 0.45 | IAI46_06540 | | ATP-dependent dethiobiotin synthetase BioD | low | > 87 |
| Escherichia coli ECRC98 | 0.69 | JDDGAC_17170 | fabR | HTH-type transcriptional repressor FabR | 0.47 | JDDGAC_02335 | bioD | dethiobiotin synthase | low | > 87 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.69 | OHPLBJKB_04087 | | HTH-type transcriptional repressor FabR | 0.47 | OHPLBJKB_02133 | | ATP-dependent dethiobiotin synthetase BioD 1 | low | > 74 |
| Escherichia coli ECRC101 | 0.69 | MCAODC_04045 | fabR | HTH-type transcriptional repressor FabR | 0.47 | MCAODC_17665 | bioD | dethiobiotin synthase | — | — |
| Escherichia coli ECRC99 | 0.69 | KEDOAH_14615 | fabR | HTH-type transcriptional repressor FabR | 0.47 | KEDOAH_00360 | bioD | dethiobiotin synthase | — | — |
| Escherichia coli ECRC62 | 0.69 | BNILDI_05835 | fabR | HTH-type transcriptional repressor FabR | 0.47 | BNILDI_17040 | bioD | dethiobiotin synthase | low | > 75 |
| Escherichia coli BL21 | 0.69 | ECD_03848 | | transcriptional repressor of fabA and fabB | 0.47 | ECD_01562 | | putative dethiobiotin synthetase | low | > 61 |
| Escherichia fergusonii Becca | 0.69 | EFB2_04647 | | HTH-type transcriptional repressor FabR | 0.47 | EFB2_02399 | | ATP-dependent dethiobiotin synthetase BioD 1 | low | > 86 |
| Dickeya dadantii 3937 | 0.69 | DDA3937_RS00980 | | HTH-type transcriptional repressor FabR | 0.45 | DDA3937_RS10680 | | ATP-dependent dethiobiotin synthetase BioD | low | > 74 |
| Rahnella sp. WP5 | 0.69 | EX31_RS14160 | | HTH-type transcriptional repressor FabR | 0.42 | EX31_RS23710 | | ATP-dependent dethiobiotin synthetase BioD | low | > 89 |
| Erwinia amylovora T8 | 0.69 | OLJFJH_06150 | | HTH-type transcriptional repressor FabR | 0.43 | OLJFJH_14270 | | dethiobiotin synthase | low | > 58 |
| Shewanella loihica PV-4 | 0.65 | Shew_0137 | | DNA-binding transcriptional repressor FabR (RefSeq) | 0.36 | Shew_1722 | | dethiobiotin synthase (RefSeq) | — | — |
| Shewanella sp. ANA-3 | 0.64 | Shewana3_0178 | | DNA-binding transcriptional repressor FabR (RefSeq) | 0.38 | Shewana3_2516 | bioD | dithiobiotin synthetase (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.64 | SO0198 | | transcriptional regulator, TetR family (NCBI ptt file) | 0.38 | SO2737 | bioD | dethiobiotin synthase (NCBI ptt file) | — | — |
| Shewanella amazonensis SB2B | 0.63 | Sama_0192 | | DNA-binding transcriptional repressor FabR (RefSeq) | 0.35 | Sama_1441 | bioD | dithiobiotin synthetase (RefSeq) | — | — |
| Kangiella aquimarina DSM 16071 | 0.61 | B158DRAFT_1831 | | transcriptional regulator, TetR family | 0.30 | B158DRAFT_0869 | | dethiobiotin synthase | — | — |
| Alteromonas macleodii MIT1002 | 0.54 | MIT1002_03371 | | HTH-type transcriptional repressor FabR | 0.32 | MIT1002_01382 | | ATP-dependent dethiobiotin synthetase BioD 1 | low | > 70 |
| Marinobacter adhaerens HP15 | 0.53 | HP15_2045 | | DNA-binding transcriptional repressor FabR | 0.37 | HP15_2482 | | dethiobiotin synthetase | low | > 73 |
| Lysobacter sp. OAE881 | 0.32 | ABIE51_RS00935 | | HTH-type transcriptional repressor FabR | 0.33 | ABIE51_RS17990 | | dethiobiotin synthase | low | > 62 |
| Pseudomonas segetis P6 | 0.27 | ACVTMO_RS06170 | | TetR family transcriptional regulator | 0.40 | ACVTMO_RS03780 | bioD | dethiobiotin synthase | low | > 75 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.27 | Psyr_4450 | | transcriptional regulator, TetR family | 0.35 | Psyr_4683 | | dethiobiotin synthase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.27 | Psyr_4450 | | transcriptional regulator, TetR family | 0.35 | Psyr_4683 | | dethiobiotin synthase | low | > 86 |
| Pseudomonas protegens RBAN4 | 0.26 | FABNJH_03155 | fabR | HTH-type transcriptional repressor FabR | 0.37 | FABNJH_28655 | bioD | dethiobiotin synthase | — | — |
| Pseudomonas sp. DMC3 | 0.26 | GFF3264 | | HTH-type transcriptional repressor FabR | 0.39 | GFF72 | | ATP-dependent dethiobiotin synthetase BioD 1 | low | > 89 |
| Pseudomonas sp. SVBP6 | 0.26 | COO64_RS18070 | | TetR family transcriptional regulator | 0.40 | COO64_RS22705 | bioD | dethiobiotin synthase | low | > 91 |
| Pseudomonas fluorescens GW456-L13 | 0.26 | PfGW456L13_110 | | Unsaturated fatty acid biosythesis repressor FabR, TetR family | 0.38 | PfGW456L13_1151 | | Dethiobiotin synthetase (EC 6.3.3.3) | low | > 87 |
| Pseudomonas fluorescens FW300-N1B4 | 0.26 | Pf1N1B4_1370 | | Unsaturated fatty acid biosythesis repressor FabR, TetR family | 0.37 | Pf1N1B4_2491 | | Dethiobiotin synthetase (EC 6.3.3.3) | low | > 87 |
| Pseudomonas fluorescens SBW25 | 0.26 | PFLU_RS02790 | | TetR family transcriptional regulator | 0.38 | PFLU_RS27630 | | dethiobiotin synthase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.26 | PFLU_RS02790 | | TetR family transcriptional regulator | 0.38 | PFLU_RS27630 | | dethiobiotin synthase | low | > 109 |
| Pseudomonas fluorescens FW300-N2E2 | 0.26 | Pf6N2E2_3568 | | Unsaturated fatty acid biosythesis repressor FabR, TetR family | 0.36 | Pf6N2E2_4764 | | Dethiobiotin synthetase (EC 6.3.3.3) | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.26 | AO356_08445 | | TetR family transcriptional regulator | 0.37 | AO356_14155 | | dethiobiotin synthetase | low | > 104 |
| Pseudomonas sp. RS175 | 0.26 | PFR28_05164 | | HTH-type transcriptional repressor FabR | 0.37 | PFR28_04099 | | ATP-dependent dethiobiotin synthetase BioD 1 | — | — |
| Pseudomonas simiae WCS417 | 0.25 | PS417_02720 | | TetR family transcriptional regulator | 0.38 | PS417_25985 | | dethiobiotin synthetase | low | > 88 |
| Pseudomonas fluorescens FW300-N2E3 | 0.25 | AO353_13415 | | TetR family transcriptional regulator | 0.36 | AO353_07505 | | dethiobiotin synthetase | low | > 101 |
| Pseudomonas sp. BP01 | 0.25 | JOY50_RS17425 | | TetR family transcriptional regulator | 0.41 | JOY50_RS17950 | bioD | dethiobiotin synthase | low | > 84 |
Not shown: 3 genomes with orthologs for CSW01_00775 only; 30 genomes with orthologs for CSW01_05660 only