Conservation of cofitness between BWI76_RS20390 and BWI76_RS08760 in Klebsiella michiganensis M5al

50 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 1.0 BWI76_RS08760 biotin synthase 0.47 18
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.91 GFF671 Biotin synthase (EC 2.8.1.6) low > 78
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.91 EX28DRAFT_2216 biotin synthase (EC 2.8.1.6) low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.90 MPMX20_01403 Biotin synthase 0.52 9
Escherichia coli BL21 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.94 ECD_00742 biotin synthase low > 61
Escherichia fergusonii Becca 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.94 EFB2_03330 Biotin synthase low > 86
Escherichia coli Nissle 1917 0.83 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.94 ECOLIN_RS04130 biotin synthase BioB low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.94 OHPLBJKB_02938 Biotin synthase low > 73
Escherichia coli BW25113 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.94 b0775 bioB biotin synthase (NCBI) low > 76
Escherichia coli ECOR27 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 NOLOHH_22770 bioB biotin synthase BioB low > 75
Escherichia coli ECRC62 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 BNILDI_21040 bioB biotin synthase BioB low > 75
Escherichia coli ECRC101 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 MCAODC_25615 bioB biotin synthase BioB 0.85 19
Escherichia coli ECRC98 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 JDDGAC_10035 bioB biotin synthase BioB low > 86
Escherichia coli ECRC100 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 OKFHMN_06400 bioB biotin synthase BioB low > 80
Escherichia coli ECRC99 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 KEDOAH_21510 bioB biotin synthase BioB — —
Escherichia coli ECRC102 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 NIAGMN_04445 bioB biotin synthase BioB — —
Escherichia coli ECOR38 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.94 HEPCGN_01640 bioB biotin synthase BioB low > 87
Dickeya dadantii 3937 0.75 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB 0.84 DDA3937_RS08510 biotin synthase BioB low > 74
Dickeya dianthicola ME23 0.74 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB 0.84 DZA65_RS08965 biotin synthase BioB low > 75
Pantoea sp. MT58 0.73 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.83 IAI47_13530 biotin synthase BioB low > 76
Erwinia tracheiphila SCR3 0.73 LU632_RS07815 DUF3410 domain-containing protein 0.84 LU632_RS09130 bioB biotin synthase BioB — —
Rahnella sp. WP5 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.83 EX31_RS23695 biotin synthase BioB low > 89
Serratia liquefaciens MT49 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.85 IAI46_06525 biotin synthase BioB low > 86
Dickeya dianthicola 67-19 0.70 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB 0.83 HGI48_RS08675 biotin synthase BioB low > 71
Pectobacterium carotovorum WPP14 0.70 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB 0.85 HER17_RS13460 biotin synthase BioB low > 75
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_10525 DUF3410 domain-containing protein 0.70 CSW01_05645 biotin synthase — —
Shewanella sp. ANA-3 0.43 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.66 Shewana3_2519 biotin synthase (RefSeq) — —
Shewanella oneidensis MR-1 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.66 SO2740 bioB biotin synthase (NCBI ptt file) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.68 Psyr_4687 biotin synthase — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.68 Psyr_4687 biotin synthase — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.68 PfGW456L13_1147 Biotin synthase (EC 2.8.1.6) — —
Shewanella amazonensis SB2B 0.42 Sama_2153 erythronate-4-phosphate dehydrogenase (RefSeq) 0.66 Sama_1438 biotin synthase (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_00545 erythronate-4-phosphate dehydrogenase 0.68 AO353_07525 biotin synthase — —
Shewanella loihica PV-4 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.65 Shew_1719 biotin synthase (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.68 Pf1N1B4_2487 Biotin synthase (EC 2.8.1.6) — —
Pseudomonas simiae WCS417 0.41 PS417_07535 erythronate-4-phosphate dehydrogenase 0.68 PS417_26005 biotin synthase — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_02365 erythronate-4-phosphate dehydrogenase 0.68 AO356_14135 biotin synthase — —
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.68 Pf6N2E2_4759 Biotin synthase (EC 2.8.1.6) — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.68 PFLU_RS27650 biotin synthase BioB — —
Pseudomonas fluorescens SBW25 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.68 PFLU_RS27650 biotin synthase BioB — —
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_1308 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) 0.62 B158DRAFT_0864 biotin synthase (EC 2.8.1.6) — —
Pseudomonas sp. RS175 0.39 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.68 PFR28_04103 Biotin synthase — —
Marinobacter adhaerens HP15 0.38 HP15_2098 erythronate-4-phosphate dehydrogenase 0.66 HP15_2486 biotin synthase — —
Pseudomonas putida KT2440 0.38 PP_2117 Erythronate-4-phosphate dehydrogenase 0.69 PP_0362 Biotin synthase — —
Pseudomonas sp. S08-1 0.37 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.69 OH686_10355 biotin synthase — —
Pseudomonas stutzeri RCH2 0.37 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.70 Psest_0411 biotin synthetase — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS10820 4-phosphoerythronate dehydrogenase PdxB 0.24 HMPREF1058_RS17950 biotin synthase BioB low > 67
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS06250 4-phosphoerythronate dehydrogenase PdxB 0.24 ABI39_RS14240 biotin synthase BioB low > 72
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS19150 4-phosphoerythronate dehydrogenase PdxB 0.25 HMPREF1078_RS15300 biotin synthase BioB 0.72 19
Alteromonas macleodii MIT1002 0.32 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.68 MIT1002_01379 Biotin synthase — —
Acinetobacter radioresistens SK82 0.31 MPMX26_02238 Erythronate-4-phosphate dehydrogenase 0.60 MPMX26_01785 Biotin synthase low > 36

Not shown: 3 genomes with orthologs for BWI76_RS20390 only; 42 genomes with orthologs for BWI76_RS08760 only