Conservation of cofitness between BWI76_RS20390 and BWI76_RS04990 in Klebsiella michiganensis M5al

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 1.0 BWI76_RS04990 pantoate--beta-alanine ligase 0.58 6
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.88 GFF92 Pantoate--beta-alanine ligase (EC 6.3.2.1) low > 78
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.85 EX28DRAFT_3729 pantoate--beta-alanine ligase low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.85 MPMX20_00826 Pantothenate synthetase 0.39 22
Escherichia coli BL21 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.89 ECD_00132 pantothenate synthetase low > 61
Escherichia fergusonii Becca 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase 0.90 EFB2_03911 Pantothenate synthetase low > 86
Escherichia coli BW25113 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.89 b0133 panC pantoate--beta-alanine ligase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase 0.89 OHPLBJKB_03528 Pantothenate synthetase low > 73
Escherichia coli ECOR27 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 NOLOHH_02750 panC pantoate--beta-alanine ligase low > 75
Escherichia coli ECRC62 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 BNILDI_08920 panC pantoate--beta-alanine ligase low > 75
Escherichia coli ECRC100 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 OKFHMN_10405 panC pantoate--beta-alanine ligase low > 80
Escherichia coli ECRC101 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 MCAODC_00920 panC pantoate--beta-alanine ligase 0.95 1
Escherichia coli ECRC99 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 KEDOAH_17750 panC pantoate--beta-alanine ligase — —
Escherichia coli ECRC102 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 NIAGMN_08255 panC pantoate--beta-alanine ligase — —
Escherichia coli ECRC98 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 JDDGAC_14000 panC pantoate--beta-alanine ligase low > 86
Escherichia coli ECOR38 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 HEPCGN_08380 panC pantoate--beta-alanine ligase 0.82 37
Dickeya dadantii 3937 0.75 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB 0.69 DDA3937_RS15960 pantoate--beta-alanine ligase low > 74
Dickeya dianthicola ME23 0.74 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB 0.70 DZA65_RS17160 pantoate--beta-alanine ligase 0.46 39
Pantoea sp. MT58 0.73 IAI47_06235 4-phosphoerythronate dehydrogenase PdxB 0.74 IAI47_15660 pantoate--beta-alanine ligase low > 76
Erwinia tracheiphila SCR3 0.73 LU632_RS07815 DUF3410 domain-containing protein 0.76 LU632_RS20105 panC pantoate--beta-alanine ligase — —
Rahnella sp. WP5 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB 0.72 EX31_RS03285 pantoate--beta-alanine ligase low > 89
Serratia liquefaciens MT49 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB 0.76 IAI46_21245 pantoate--beta-alanine ligase low > 86
Dickeya dianthicola 67-19 0.70 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB 0.68 HGI48_RS16075 pantoate--beta-alanine ligase low > 71
Pectobacterium carotovorum WPP14 0.70 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB 0.73 HER17_RS05555 pantoate--beta-alanine ligase low > 75
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_10525 DUF3410 domain-containing protein 0.57 CSW01_03130 pantoate--beta-alanine ligase — —
Shewanella sp. ANA-3 0.43 Shewana3_1476 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region (RefSeq) 0.46 Shewana3_3409 panC pantoate--beta-alanine ligase (RefSeq) — —
Shewanella oneidensis MR-1 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.46 SO0869 panC pantoate--beta-alanine ligase (NCBI ptt file) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.54 Psyr_0827 pantothenate synthetase — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1828 4-phosphoerythronate dehydrogenase 0.54 Psyr_0827 pantothenate synthetase — —
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_4048 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.52 PfGW456L13_1520 Pantoate--beta-alanine ligase (EC 6.3.2.1) — —
Shewanella amazonensis SB2B 0.42 Sama_2153 erythronate-4-phosphate dehydrogenase (RefSeq) 0.46 Sama_0775 panC pantoate--beta-alanine ligase (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_00545 erythronate-4-phosphate dehydrogenase 0.51 AO353_14380 pantoate--beta-alanine ligase — —
Shewanella loihica PV-4 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.46 Shew_3134 pantoate--beta-alanine ligase (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3893 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.50 Pf1N1B4_2853 Pantoate--beta-alanine ligase (EC 6.3.2.1) — —
Pseudomonas simiae WCS417 0.41 PS417_07535 erythronate-4-phosphate dehydrogenase 0.49 PS417_23915 pantoate--beta-alanine ligase — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_02365 erythronate-4-phosphate dehydrogenase 0.51 AO356_16055 pantoate--beta-alanine ligase — —
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_2297 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) 0.51 Pf6N2E2_5152 Pantoate--beta-alanine ligase (EC 6.3.2.1) — —
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.49 PFLU_RS25755 pantoate--beta-alanine ligase — —
Pseudomonas fluorescens SBW25 0.40 PFLU_RS07615 4-phosphoerythronate dehydrogenase PdxB 0.49 PFLU_RS25755 pantoate--beta-alanine ligase — —
Kangiella aquimarina DSM 16071 0.40 B158DRAFT_1308 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) 0.48 B158DRAFT_0062 pantoate--beta-alanine ligase — —
Pseudomonas sp. RS175 0.39 PFR28_01103 Erythronate-4-phosphate dehydrogenase 0.52 PFR28_03722 Pantothenate synthetase — —
Marinobacter adhaerens HP15 0.38 HP15_2098 erythronate-4-phosphate dehydrogenase 0.50 HP15_323 pantothenate synthetase — —
Pseudomonas putida KT2440 0.38 PP_2117 Erythronate-4-phosphate dehydrogenase 0.51 PP_4700 pantothenate synthetase — —
Pseudomonas sp. S08-1 0.37 OH686_02070 Erythronate-4-phosphate dehydrogenase 0.52 OH686_17240 pantoate--beta-alanine ligase — —
Pseudomonas stutzeri RCH2 0.37 Psest_2548 Phosphoglycerate dehydrogenase and related dehydrogenases 0.50 Psest_0995 pantoate--beta-alanine ligase — —
Bacteroides stercoris CC31F 0.34 HMPREF1181_RS02440 4-phosphoerythronate dehydrogenase PdxB 0.39 HMPREF1181_RS06090 pantoate--beta-alanine ligase — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS10820 4-phosphoerythronate dehydrogenase PdxB 0.40 HMPREF1058_RS18260 pantoate--beta-alanine ligase — —
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS06250 4-phosphoerythronate dehydrogenase PdxB 0.40 ABI39_RS14555 pantoate--beta-alanine ligase — —
Parabacteroides merdae CL09T00C40 0.33 HMPREF1078_RS19150 4-phosphoerythronate dehydrogenase PdxB 0.38 HMPREF1078_RS14680 pantoate--beta-alanine ligase 0.67 36
Bacteroides ovatus ATCC 8483 0.33 BACOVA_01953 4-phosphoerythronate dehydrogenase 0.40 BACOVA_05108 pantoate--beta-alanine ligase — —
Bacteroides thetaiotaomicron VPI-5482 0.32 BT3361 erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.39 BT4308 pantoate--beta-alanine ligase (NCBI ptt file) — —
Alteromonas macleodii MIT1002 0.32 MIT1002_02532 Erythronate-4-phosphate dehydrogenase 0.46 MIT1002_03695 Pantothenate synthetase — —
Acinetobacter radioresistens SK82 0.31 MPMX26_02238 Erythronate-4-phosphate dehydrogenase 0.41 MPMX26_00546 Pantothenate synthetase — —

Not shown: 1 genomes with orthologs for BWI76_RS20390 only; 45 genomes with orthologs for BWI76_RS04990 only